| Sequence 1: | NP_001259153.1 | Gene: | Ocrl / 31157 | FlyBaseID: | FBgn0023508 | Length: | 850 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001017915.1 | Gene: | INPP5D / 3635 | HGNCID: | 6079 | Length: | 1189 | Species: | Homo sapiens |
| Alignment Length: | 633 | Identity: | 155/633 - (24%) |
|---|---|---|---|
| Similarity: | 259/633 - (40%) | Gaps: | 164/633 - (25%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 5 SEAVANGTATA--ATRTTKDIVKERFKED-------ETIEYIFEAYQIKG----PEYSNRLLALV 56
Fly 57 SSQSGGTFAIIAFSYLRTPLSSANELIINKVFAIDH---------------NFQLRQDS------ 100
Fly 101 ---KSSITTQQFDLSTAEDGPIKYYYYATESH-------HYEEFVAKVISFKSTMAQHDPETVL- 154
Fly 155 -NFRWLNDYRQIG--EVKQELKKRESEYIVYKDIIIYCATWNVNN-----------------KTC 199
Fly 200 SDSNNPLRAWLACSEKPPDIYAIGLQELDTPTKAMLNSTQVQAIEKQWIDKMMDSVH--PDVEYE 262
Fly 263 ILMSHRLVATMLTVIVRKQLRQHIIRCRPKSVARGIFNTLGNKGGVAISLQLNEGNICFVNSHLA 327
Fly 328 AHMGYVEERNQDYNAIVEGIRFDDGRTISDHD------HIFWVGDLNYRIQEPPGQ-----QRPG 381
Fly 382 PLSDAQTYELLLQYDQLRQEMRRGKCFEGYTEGEIKFRPTYKYDPGTDNYDSSEKQRA------- 439
Fly 440 PAYCDRVLWKGTRIEQL---AYNSIMEIRQSDHKPVYAVFQVKV--------------------- 480
Fly 481 -------KTRDEVK-YKRVQEEVLKAVDKRENDNQPQINVEKTVIDFG 520 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Ocrl | NP_001259153.1 | PH-like | 23..163 | CDD:302622 | 30/183 (16%) |
| INPP5c_INPP5B | 185..478 | CDD:197327 | 105/332 (32%) | ||
| RhoGAP_OCRL1 | 614..823 | CDD:239845 | |||
| INPP5D | NP_001017915.1 | SH2_SHIP | 1..102 | CDD:198206 | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 103..132 | ||||
| SH3-binding 1 | 124..129 | ||||
| INPP5c_SHIP1-INPP5D | 404..710 | CDD:197334 | 105/332 (32%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 870..906 | ||||
| PHA03307 | 899..>1127 | CDD:223039 | |||
| NPXY motif 1 | 912..915 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 922..1189 | ||||
| SH3-binding 2 | 969..974 | ||||
| Interaction with DAB2. /evidence=ECO:0000250 | 1016..1030 | ||||
| NPXY motif 2 | 1019..1022 | ||||
| SH3-binding 3 | 1040..1051 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5411 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||