DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ocrl and CG9784

DIOPT Version :9

Sequence 1:	NP_001259153.1	Gene:	Ocrl / 31157	FlyBaseID:	FBgn0023508	Length:	850	Species:	Drosophila melanogaster
Sequence 2:	NP_001259623.1	Gene:	CG9784 / 32629	FlyBaseID:	FBgn0030761	Length:	519	Species:	Drosophila melanogaster

Alignment Length:	386	Identity:	113/386 - (29%)
Similarity:	175/386 - (45%)	Gaps:	71/386 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   166 GEVKQELKKRESEYIVYKDIIIYCATWNVNNKTCSDSNNPLRAWLACSEKP------------PD 218
            |:.||:|:       .|:   :|..||||.::  ...|..||..|...:..            ||
  Fly    22 GKGKQQLE-------TYR---VYVVTWNVGSR--FPDNISLRHLLGLQDVTVDKDTKETNAHLPD 74

  Fly   219 IYAIGLQELDT-PTKAMLNSTQVQAIEKQWIDKMMDSVHPDVEYEILMSHRLVATMLTVIVRKQL 282
            |||:||||::. |.:.:|...:    |..|..|..:.:. :.:|..:.:.::...:|::.||:|.
  Fly    75 IYALGLQEVNAQPQQQVLGLFK----EDPWTHKAKELLR-NYDYVAVKTEQMQGLLLSMFVRRQH 134

  Fly   283 RQHIIRCRPKSVARGIFNTLGNKGGVAISLQLNEGNICFVNSHLAAHMGYVEERNQDYNAIVEGI 347
            .:|:.....:....|.....||||.|::...|....:.||.:||.||...::||.:||..|:|..
  Fly   135 VEHLQDIEAEFTRTGFGGIWGNKGAVSVRFTLYGCGLAFVVAHLTAHDHMMDERIEDYKQILENH 199

  Fly   348 RF--DDGRTISDHDHIFWVGDLNYRIQEPPGQQRPGPL-SDAQTYELLLQYDQLRQEMRRGK-CF 408
            .:  ...|.|.|||::||.||||:|:|..........| .|...:|.|:|.|||.|...:.: .|
  Fly   200 HYHVKRYREIYDHDYVFWFGDLNFRLQGSDSSTEVRELVRDESQHEALIQRDQLYQVREKSQLAF 264

  Fly   409 EGYTEGEIKFRPTYKYDPGTDNYDSSEKQRAPAYCDRVLW--------KGTR--IEQLAYNSIME 463
            :...|....|.||:|:..||..||   .:|.||:.||:::        .|.:  |||.:|.|...
  Fly   265 QVLQERLPAFPPTFKFREGTSEYD---LKRRPAWTDRIMYAVQPLNRQPGMQLSIEQCSYKSHPL 326

  Fly   464 IRQSDHKPVYAVFQVKV-----------------KTRDE--VKYKRVQEEVLKAVDKREND 505
            ...||||||.:.|.:|:                 |..||  |:|.:..|     .|:..||
  Fly   327 YTISDHKPVTSDFTIKLYPNVRAPGVVFSPLSLWKIGDENTVEYHKQAE-----FDEGSND 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ocrl	NP_001259153.1	PH-like	23..163	CDD:302622
		INPP5c_INPP5B	185..478	CDD:197327	98/319 (31%)
		RhoGAP_OCRL1	614..823	CDD:239845
CG9784	NP_001259623.1	INPP5c_INPP5J-like	31..341	CDD:197328	99/322 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447404
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5411
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D105940at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11200
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850