DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ocrl and Inpp5k

DIOPT Version :9

Sequence 1:	NP_001259153.1	Gene:	Ocrl / 31157	FlyBaseID:	FBgn0023508	Length:	850	Species:	Drosophila melanogaster
Sequence 2:	NP_001013881.1	Gene:	Inpp5k / 287533	RGDID:	1359130	Length:	446	Species:	Rattus norvegicus

Alignment Length:	348	Identity:	109/348 - (31%)
Similarity:	163/348 - (46%)	Gaps:	54/348 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   187 IYCATWNVNNKT----CSD----SNNPLRAWLACSEKPPDIYAIGLQELDTPTKAMLNSTQVQAI 243
            |:..||||.:..    .||    :|..|..         |||.|||||::....::|:..   |.
  Rat    19 IHVVTWNVASAAPTVDLSDLLQLNNEDLNL---------DIYIIGLQEMNYGIISLLSDA---AF 71

  Fly   244 EKQWIDKMMDSVHPDVEYEILMSHRLVATMLTVIVRKQLRQHIIRCRPKSVARGIFNTLGNKGGV 308
            |..|....||.:.| :....:...|:...:|.|..:.|...:|.....||:..|::...|||||:
  Rat    72 EDPWSSFFMDMLSP-LNLVKISQVRMQGLLLLVFAKYQHLPYIQIISTKSIPTGLYGYWGNKGGI 135

  Fly   309 AISLQLNEGNICFVNSHLAAHMGYVEERNQDYNAIVEGIRFD--DGRTISDHDHIFWVGDLNYRI 371
            .|.|:|....:..||.||..||...::|.:.::.|:|.:.|:  |...|.|||.|.|.||:|:||
  Rat   136 NICLKLYGYYVSIVNCHLPPHMYNNDQRLEHFDRILESLTFEGYDVPNILDHDLILWFGDMNFRI 200

  Fly   372 --------QEPPGQQRPGPLSDAQTYELLLQYDQLRQEMRRGKCFEGYTEGEIKFRPTYKYDPGT 428
                    ||...::|         |:.|.:.|||....::.:....:.||.:.|.||||:|..:
  Rat   201 EDFGLLFVQECITKKR---------YKELWEKDQLFIAKKQDQLLREFQEGPLLFPPTYKFDRHS 256

  Fly   429 DNYDSSEKQRAPAYCDRVLWK-----------GTRIEQLAYNSIMEIRQSDHKPVYAVFQVKVKT 482
            :|||:|||:|.||:.||:||:           |..:.|..|.|.|....||||||...|.:::..
  Rat   257 NNYDTSEKKRKPAWTDRILWRLKRQPAKANPSGFLLTQKDYVSHMTYSISDHKPVTGTFDLELNP 321

  Fly   483 RDEVKYKRVQEEVLKAVDKREND 505
            ...|....:..|.|..   :|||
  Rat   322 LMSVPLITMMPEYLWT---KEND 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ocrl	NP_001259153.1	PH-like	23..163	CDD:302622
		INPP5c_INPP5B	185..478	CDD:197327	103/319 (32%)
		RhoGAP_OCRL1	614..823	CDD:239845
Inpp5k	NP_001013881.1	EEP	17..317	CDD:294334	103/319 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910