Protein Alignment Ocrl and Inpp5k

DIOPT Version :10

• Sequence 1: NP_569962.2
• Gene: Ocrl / 31157
• FlyBaseID: FBgn0023508
• Length: 850
• Species: Drosophila melanogaster
• Sequence 2: NP_001013881.1
• Gene: Inpp5k / 287533
• RGDID: 1359130
• Length: 446
• Species: Rattus norvegicus
• Alignment Length: 348
• Identity: 109/348 - (31%)
• Similarity: 163/348 - (46%)
• Gaps: 54/348 - (15%)

  Fly   187 IYCATWNVNNKT----CSD----SNNPLRAWLACSEKPPDIYAIGLQELDTPTKAMLNSTQVQAI 243
            |:..||||.:..    .||    :|..|..         |||.|||||::....::|:..   |.
  Rat    19 IHVVTWNVASAAPTVDLSDLLQLNNEDLNL---------DIYIIGLQEMNYGIISLLSDA---AF 71

  Fly   244 EKQWIDKMMDSVHPDVEYEILMSHRLVATMLTVIVRKQLRQHIIRCRPKSVARGIFNTLGNKGGV 308
            |..|....||.:.| :....:...|:...:|.|..:.|...:|.....||:..|::...|||||:
  Rat    72 EDPWSSFFMDMLSP-LNLVKISQVRMQGLLLLVFAKYQHLPYIQIISTKSIPTGLYGYWGNKGGI 135

  Fly   309 AISLQLNEGNICFVNSHLAAHMGYVEERNQDYNAIVEGIRFD--DGRTISDHDHIFWVGDLNYRI 371
            .|.|:|....:..||.||..||...::|.:.::.|:|.:.|:  |...|.|||.|.|.||:|:||
  Rat   136 NICLKLYGYYVSIVNCHLPPHMYNNDQRLEHFDRILESLTFEGYDVPNILDHDLILWFGDMNFRI 200

  Fly   372 --------QEPPGQQRPGPLSDAQTYELLLQYDQLRQEMRRGKCFEGYTEGEIKFRPTYKYDPGT 428
                    ||...::|         |:.|.:.|||....::.:....:.||.:.|.||||:|..:
  Rat   201 EDFGLLFVQECITKKR---------YKELWEKDQLFIAKKQDQLLREFQEGPLLFPPTYKFDRHS 256

  Fly   429 DNYDSSEKQRAPAYCDRVLWK-----------GTRIEQLAYNSIMEIRQSDHKPVYAVFQVKVKT 482
            :|||:|||:|.||:.||:||:           |..:.|..|.|.|....||||||...|.:::..
  Rat   257 NNYDTSEKKRKPAWTDRILWRLKRQPAKANPSGFLLTQKDYVSHMTYSISDHKPVTGTFDLELNP 321

  Fly   483 RDEVKYKRVQEEVLKAVDKREND 505
            ...|....:..|.|..   :|||
  Rat   322 LMSVPLITMMPEYLWT---KEND 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ocrl	NP_569962.2	INPP5B_PH	23..160	CDD:465268
		INPP5c_INPP5B	185..478	CDD:197327	103/319 (32%)
		RhoGAP_OCRL1	614..823	CDD:239845
Inpp5k	NP_001013881.1	EEP	17..317	CDD:469791	103/319 (32%)
		SKICH	328..428	CDD:465482	5/17 (29%)