Protein Alignment Ocrl and inp53

DIOPT Version :10

• Sequence 1: NP_569962.2
• Gene: Ocrl / 31157
• FlyBaseID: FBgn0023508
• Length: 850
• Species: Drosophila melanogaster
• Sequence 2: NP_593565.1
• Gene: inp53 / 2542329
• PomBaseID: SPAC9G1.10C
• Length: 1191
• Species: Schizosaccharomyces pombe
• Alignment Length: 458
• Identity: 132/458 - (28%)
• Similarity: 201/458 - (43%)
• Gaps: 95/458 - (20%)

  Fly   109 FDLSTAEDGPIKYYYYATESHH-------------YEEFVAKVISFKSTMAQHDPETVLNFRWLN 160
            ||:|.:....:|.::....||:             ::....:|:|..|        :|:.| |
pombe   710 FDVSESPWRLLKSWHGHKASHNGATTILGIDVNSVWKAKRLQVVSMAS--------SVVKF-W-- 763

  Fly   161 DYRQIGE-VKQELKKRESEYIVYKDIIIYCATWNVNNKTCSDSNNPLRAWLACSEKP-------- 216
            |...:|: :..|::.|..||..:.|:.|...:||......||.::..   :..|..|
pombe   764 DGLMMGDWLATEMRSRFPEYSNFTDVSILICSWNAGASKPSDLDSDT---IGASMIPMMIRDNGY 825

  Fly   217 PDIYAIGLQEL-DTPTKAML---------------NSTQVQAIEKQWIDKM---MDSVHPDVEYE 262
            |||...|.||| |...|.:.               ||..:.:..:.|.:|:   |..|..:.:|:
pombe   826 PDIVVFGFQELVDLENKRLTARSILSKSSSKGGSSNSANISSQYRLWREKLESEMMRVSSNDDYQ 890

  Fly   263 ILMSHRLVATMLTVIVRKQLRQHIIRCRPKSVARGIFNTLGNKGGVAISLQLNEGNICFVNSHLA 327
            :|:...||.....|.|:.:|:..|...:..:|..|:....||||.:.:...:::.:.|.||.|||
pombe   891 VLVCENLVGLFSCVFVKNKLQSKIRMLQSTTVKTGLGGLHGNKGAIVVRFLVDDTSYCIVNCHLA 955

  Fly   328 AHMGYVEERNQDYNAIVEG----------------IRFDDGRTISDHDHIFWVGDLNYRIQEPPG 376
            |.......||.|...|::.                :...||..|.||:.....|||||||    .
pombe   956 AGQSNKAARNNDLATILDNASLFPENDETDQLNTFVGGGDGSLIMDHEVCVLHGDLNYRI----N 1016

  Fly   377 QQRPGPL-----SDAQTYELLLQYDQLRQEMRRGKCF--EGYTEGEIKFRPTYKYDPGTDNYDSS 434
            ..||..|     :|.:|   |||.|||..|.:|...|  ..:||.||.|.||||||..::.||||
pombe  1017 TLRPKALDLIKKNDIKT---LLQSDQLLVERKRNAGFRLRTFTEPEITFAPTYKYDVHSEQYDSS 1078

  Fly   435 EKQRAPAYCDRVLWKGTRIEQLAYN-SIMEIRQSDHKPVYAVFQVKVK---------TRDEVKYK 489
            ||:|.||:|||:.::|:.....|.| :..|::.|||:||.|:...|.|         |.|.||.|
pombe  1079 EKKRVPAWCDRICYRGSPDYISAENYTRYELKASDHRPVSALIHSKAKMVNAQSQGSTWDVVKRK 1143

  Fly   490 RVQ 492
            .::
pombe  1144 WIE 1146

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ocrl	NP_569962.2	INPP5B_PH	23..160	CDD:465268	12/63 (19%)
		INPP5c_INPP5B	185..478	CDD:197327	106/343 (31%)
		RhoGAP_OCRL1	614..823	CDD:239845
inp53	NP_593565.1	COG5411	281..794	CDD:227698	20/94 (21%)
		IPPc	787..1126	CDD:214525	108/348 (31%)
		UBA_TAP-C_like	1161..1186	CDD:270459