Protein Alignment Ocrl and Synj2

DIOPT Version :9

• Sequence 1: NP_001259153.1
• Gene: Ocrl / 31157
• FlyBaseID: FBgn0023508
• Length: 850
• Species: Drosophila melanogaster
• Sequence 2: NP_001106824.1
• Gene: Synj2 / 20975
• MGIID: 1201671
• Length: 1479
• Species: Mus musculus
• Alignment Length: 630
• Identity: 165/630 - (26%)
• Similarity: 256/630 - (40%)
• Gaps: 163/630 - (25%)

  Fly   168 VKQELKKRESEYIVYKDIIIYCATWNVNNKTCSDSN----NPLRAWLACSEK------------P 216
            :.:.:.:|:||:..:|.|.|...|||||......||    ..|..||..:.:            |
Mouse   513 ILKAMTERQSEFTNFKRIQIAVGTWNVNGGKQFRSNLLGTAELTDWLLDAPQLSGAVDSQDDGSP 577

  Fly   217 PDIYAIGLQEL-DTPTKAMLNSTQVQAIEKQWIDKMMDSVHPDVEYEILMSHRLVATMLTVIVRK 280
            .|::|||.:|: :.....::|::...  .|.|.:::..::.....|.:|.|.:||...|.:.||.
Mouse   578 ADVFAIGFEEMVELSAGNIVNASTTN--RKMWGEQLQKAISRSHRYILLTSAQLVGVCLYIFVRP 640

  Fly   281 QLRQHIIRCRPKSVARGIFNTLGNKGGVAISLQLNEGNICFVNSHLAAHMGYVEERNQDYNAIVE 345
            .....|......:|..|:....||||.|.|..||:..:.|||.|||.|....|:|||:||..|..
Mouse   641 YHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQLHSTSFCFVCSHLTAGQSQVKERNEDYREITH 705

  Fly   346 GIRFDDGRTISDHDHIFWVGDLNYRIQEPPGQQRPGPLSDAQTYE------------LLLQYDQL 398
            .:.|..||.|..||::||.||.||||.              .|||            .|:::|||
Mouse   706 KLSFPSGRNIFSHDYVFWCGDFNYRID--------------LTYEEVFYFVKRQDWKKLMEFDQL 756

  Fly   399 RQEMRRGKCFEGYTEGEIKFRPTYKYDPGTDNYDSSEKQRAPAYCDRVLW--------------- 448
            :.:...||.|:.:.||.:.|.||||||.|:..||:|:|.|.||:.|||||
Mouse   757 QLQKSSGKIFKDFHEGAVNFGPTYKYDVGSAAYDTSDKCRTPAWTDRVLWWRKKHPYDKTAGELN 821

  Fly   449 -----------------KGTRIEQLAYNSIMEIRQSDHKPVYAVFQVKVKTRDEVKYKRVQEEV- 495
                             .||    |.|....|::.|||:||.|:.:|:|:..|....:||.:||
Mouse   822 LLDSDLDGDPQIRHTWSPGT----LKYYGRAELQASDHRPVLAIVEVEVQEVDVGARERVFQEVS 882

  Fly   496 -----LKAV-----------DKRENDNQPQINVEKTVIDFGT---VRFNEPSTRDFNVYNNCPLP 541
                 |.|.           :|.|.....:..:.:|:.::||   ||.|:..           :.
Mouse   883 SVQGPLDATVVVNLQSPTLEEKNEFPEDLRTELMQTLGNYGTIILVRINQGQ-----------ML 936

  Fly   542 VDFSFKEKDIHAICEPWLHVD------------PRQDSLLIDSARSIRLKMNANVRTIAGLLRKI 594
            |.|:    |.|:.... |.||            |:....| :..|...|:...::..::......
Mouse   937 VTFA----DSHSALSV-LDVDGMKVKGRAVKIRPKTKDWL-EGLREELLRKRDSMAPVSPTANSC 995

  Fly   595 RASDNFDILILHVENGRDIFITVTGDYQPSCFGLSMETMCRTDRPL---SEYSQDQIKQLMND-- 654
            ...:|||...|..|:..|: :....||....||          :|:   ||...|.....|:.
Mouse   996 LLEENFDFSSLDYESEGDV-LEEDEDYLVDGFG----------QPVVSDSELGGDNSSDTMSSLT 1049

  Fly   655 ------------ESPEYR-----VTMPREFFLLIDYLYRQGSKQV 682
                        :.|.|:     ||:.:|..:..::.:|..|:.:
Mouse  1050 PASKSPALAKKKQHPTYKDDAHLVTLKQELEVAGNFRHRSPSRSL 1094

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ocrl	NP_001259153.1	PH-like	23..163	CDD:302622
		INPP5c_INPP5B	185..478	CDD:197327	111/353 (31%)
		RhoGAP_OCRL1	614..823	CDD:239845	16/91 (18%)
Synj2	NP_001106824.1	Syja_N	61..342	CDD:280532
		EEP	530..861	CDD:294334	110/350 (31%)
		DUF1866	872..1008	CDD:286093	29/152 (19%)
		CEND1	1290..>1405	CDD:292305

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810