Protein Alignment Ocrl and inpp5d

DIOPT Version :9

• Sequence 1: NP_001259153.1
• Gene: Ocrl / 31157
• FlyBaseID: FBgn0023508
• Length: 850
• Species: Drosophila melanogaster
• Sequence 2: XP_031758425.1
• Gene: inpp5d / 100497417
• XenbaseID: XB-GENE-6071358
• Length: 1111
• Species: Xenopus tropicalis
• Alignment Length: 491
• Identity: 128/491 - (26%)
• Similarity: 204/491 - (41%)
• Gaps: 95/491 - (19%)

  Fly    50 NRLLALVSSQSGGTFAIIAFSYLRTPLSSANELIINKVFAIDHN--------FQLRQDS------ 100
            |:|..|.|..||              |....:.::.:..|:.|.        |:::.||
 Frog   260 NKLTHLTSMVSG--------------LEEKVKTVLMEGAAVKHRRSLIPPIIFEVKADSLGISQK 310

  Fly   101 ---KSSITTQQFDLSTAEDGPIKYYY------YATESHHYEEFVAKVISFKSTMAQHDPETVLNF 156
               |..:.|.:..:..::|||...:|      ...:|..:...:..|:..:....|.......:.
 Frog   311 THLKVDVETGKLIIKKSKDGPDDKFYPSKKILQLIKSQKFPNKLVIVLETEKEKTQRKEYVFADS 375

  Fly   157 RWLNDYRQIGEVKQELKKRESEYIVYKDIIIYCATWNVNNKTCSDSNNPLRAWLACSEK------ 215
            :....:.|:   .|::|.:.|.......:.|:..|:|:.:.....:..|   |..|..:
 Frog   376 KKREGFCQL---LQQMKNKHSGQSEPDMLSIFIGTYNMGDAPPPKNITP---WFLCKGQGKTRDD 434

  Fly   216 -----PPDIYAIGLQELDTPTKAMLNSTQVQAIEKQWIDKMMDSVH--PDVEYEILMSHRLVATM 273
                 ..|||.||.||  .|..           ||:|.|.:|:|:.  ..|||:::....|....
 Frog   435 TADYIEHDIYVIGTQE--DPLS-----------EKEWTDILMNSLREITSVEYKVITIQTLWNIR 486

  Fly   274 LTVIVRKQLRQHIIRCRPKSVARGIFNTLGNKGGVAISLQLNEGNICFVNSHLAAHMGYVEERNQ 338
            :.|:.:.:....|......||..||.|||||||.|..:...|..:..|:||||.:.......|||
 Frog   487 IVVLAKPEHAHRISHVFTNSVKTGIANTLGNKGAVGAAFMFNGTSFGFINSHLTSGSEKKLRRNQ 551

  Fly   339 DYNAIVEGIRFDDGRTISDHD------HIFWVGDLNYRIQEPPGQ-----QRPGPLSDAQTYELL 392
            :|..|:..:...| :.:|..:      |:||:||||||:|.|..:     |:    ...|.|:.|
 Frog   552 NYFNILRFLILGD-KKLSPFNLTHRFTHLFWLGDLNYRLQLPNTEAENIIQK----IKQQQYQEL 611

  Fly   393 LQYDQLRQEMRRGKCFEGYTEGEIKFRPTYKYDPGTDNYDSSEKQRA-------PAYCDRVLWKG 450
            |.:|||..|.:....|..:.|.||.|.|||:::.|:.......||:|       |::|||||||.
 Frog   612 LAHDQLNLERKENLIFFQFDEEEITFPPTYRFERGSRERYCYTKQKATGIKYNLPSWCDRVLWKS 676

  Fly   451 ---TRIEQLAYNSIMEIRQSDHKPVYAVFQVKVKTR 483
               ..|...:|....:|..|||.||:..|||.|.::
 Frog   677 YPHMHILCQSYGCTDDITTSDHSPVFCTFQVGVTSQ 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ocrl	NP_001259153.1	PH-like	23..163	CDD:302622	21/135 (16%)
		INPP5c_INPP5B	185..478	CDD:197327	100/326 (31%)
		RhoGAP_OCRL1	614..823	CDD:239845
inpp5d	XP_031758425.1	SH2_SHIP	4..102	CDD:198206
		EEP	401..707	CDD:412407	100/326 (31%)
		PHA03247	<914..1108	CDD:223021

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000