Protein Alignment Ocrl and inpp5d

DIOPT Version :10

• Sequence 1: NP_569962.2
• Gene: Ocrl / 31157
• FlyBaseID: FBgn0023508
• Length: 850
• Species: Drosophila melanogaster
• Sequence 2: XP_031758425.1
• Gene: inpp5d / 100497417
• XenbaseID: XB-GENE-6071358
• Length: 1111
• Species: Xenopus tropicalis
• Alignment Length: 491
• Identity: 128/491 - (26%)
• Similarity: 204/491 - (41%)
• Gaps: 95/491 - (19%)

  Fly    50 NRLLALVSSQSGGTFAIIAFSYLRTPLSSANELIINKVFAIDHN--------FQLRQDS------ 100
            |:|..|.|..||              |....:.::.:..|:.|.        |:::.||
 Frog   260 NKLTHLTSMVSG--------------LEEKVKTVLMEGAAVKHRRSLIPPIIFEVKADSLGISQK 310

  Fly   101 ---KSSITTQQFDLSTAEDGPIKYYY------YATESHHYEEFVAKVISFKSTMAQHDPETVLNF 156
               |..:.|.:..:..::|||...:|      ...:|..:...:..|:..:....|.......:.
 Frog   311 THLKVDVETGKLIIKKSKDGPDDKFYPSKKILQLIKSQKFPNKLVIVLETEKEKTQRKEYVFADS 375

  Fly   157 RWLNDYRQIGEVKQELKKRESEYIVYKDIIIYCATWNVNNKTCSDSNNPLRAWLACSEK------ 215
            :....:.|:   .|::|.:.|.......:.|:..|:|:.:.....:..|   |..|..:
 Frog   376 KKREGFCQL---LQQMKNKHSGQSEPDMLSIFIGTYNMGDAPPPKNITP---WFLCKGQGKTRDD 434

  Fly   216 -----PPDIYAIGLQELDTPTKAMLNSTQVQAIEKQWIDKMMDSVH--PDVEYEILMSHRLVATM 273
                 ..|||.||.||  .|..           ||:|.|.:|:|:.  ..|||:::....|....
 Frog   435 TADYIEHDIYVIGTQE--DPLS-----------EKEWTDILMNSLREITSVEYKVITIQTLWNIR 486

  Fly   274 LTVIVRKQLRQHIIRCRPKSVARGIFNTLGNKGGVAISLQLNEGNICFVNSHLAAHMGYVEERNQ 338
            :.|:.:.:....|......||..||.|||||||.|..:...|..:..|:||||.:.......|||
 Frog   487 IVVLAKPEHAHRISHVFTNSVKTGIANTLGNKGAVGAAFMFNGTSFGFINSHLTSGSEKKLRRNQ 551

  Fly   339 DYNAIVEGIRFDDGRTISDHD------HIFWVGDLNYRIQEPPGQ-----QRPGPLSDAQTYELL 392
            :|..|:..:...| :.:|..:      |:||:||||||:|.|..:     |:    ...|.|:.|
 Frog   552 NYFNILRFLILGD-KKLSPFNLTHRFTHLFWLGDLNYRLQLPNTEAENIIQK----IKQQQYQEL 611

  Fly   393 LQYDQLRQEMRRGKCFEGYTEGEIKFRPTYKYDPGTDNYDSSEKQRA-------PAYCDRVLWKG 450
            |.:|||..|.:....|..:.|.||.|.|||:::.|:.......||:|       |::|||||||.
 Frog   612 LAHDQLNLERKENLIFFQFDEEEITFPPTYRFERGSRERYCYTKQKATGIKYNLPSWCDRVLWKS 676

  Fly   451 ---TRIEQLAYNSIMEIRQSDHKPVYAVFQVKVKTR 483
               ..|...:|....:|..|||.||:..|||.|.::
 Frog   677 YPHMHILCQSYGCTDDITTSDHSPVFCTFQVGVTSQ 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ocrl	NP_569962.2	INPP5B_PH	23..160	CDD:465268	21/132 (16%)
		INPP5c_INPP5B	185..478	CDD:197327	100/326 (31%)
		RhoGAP_OCRL1	614..823	CDD:239845
inpp5d	XP_031758425.1	SH2_SHIP	4..102	CDD:198206
		EEP	401..707	CDD:469791	100/326 (31%)
		PHA03247	<914..1108	CDD:223021