Protein Alignment Ocrl and emilin2

DIOPT Version :10

• Sequence 1: NP_569962.2
• Gene: Ocrl / 31157
• FlyBaseID: FBgn0023508
• Length: 850
• Species: Drosophila melanogaster
• Sequence 2: XP_012820783.1
• Gene: emilin2 / 100491397
• XenbaseID: XB-GENE-978931
• Length: 1166
• Species: Xenopus tropicalis
• Alignment Length: 678
• Identity: 122/678 - (17%)
• Similarity: 227/678 - (33%)
• Gaps: 215/678 - (31%)

  Fly    78 SANELIINKVFAIDHNFQLRQDSKSSITTQQFDLSTAEDGPIKYYYYATESHHYEEFVAK----V 138
            :.|:.|..|......|.|..|::|..:...| :|:.|::..|         |..|:.:.:    |
 Frog   148 TGNKGIGGKDIGTGINRQKPQEAKGQLQELQ-NLNEAQEKKI---------HFLEDEMLRLTQTV 202

  Fly   139 ISFKSTMA----------QHDPETVLNFRWLNDYRQ--------------------------IGE 167
            |..::::|          |.|....| ..|||:..:                          :.:
 Frog   203 IDMQTSLAGVNENLKITIQEDVSKNL-VSWLNNLPRPESFSGGKTETITFQGFSGSTEKEDGVRD 266

  Fly   168 VKQELKKRESEYIVYKDIIIYCATWNVNNKTCSDSNNPLRAWLACSEKP-PDIYAIGLQELDTPT 231
            :..||...: |.:..|.::|     :..|:..:.....||.:...|..| |.|:.:...|
 Frog   267 IISELNSMK-EALQSKSLLI-----DKLNEKLNGYEESLRQFQEASHGPAPTIHTVSAPE----- 320

  Fly   232 KAMLNSTQ--VQAIEKQWIDKM---MDSVHPDVEYEILMSHRLVATMLTVIVRKQLRQHIIRC-- 289
                ||.:  ::|:..:.:|.|   |..:....:|::            ..|::|...|...|
 Frog   321 ----NSIEEKLEALRDEMLDGMDRKMADLKNSCDYKL------------TSVQQQCEDHETSCLG 369

  Fly   290 -----RPKSV-ARGIFNTLGNKGGVAISLQLNEGNICFVNSHLAAHMGYVEERNQDYNAIVEGIR 348
                 |.|.. .|...|.:.::||:    |.|..:.|..|..|.:.:.:::::       ||  |
 Frog   370 VIELLREKETQLRKEINAVKSQGGI----QGNGQSCCTNNGDLDSKIKHLDQK-------VE--R 421

  Fly   349 FDDGRTISDHDHIFWVGDLNYRIQEPPGQQRPGPLSDAQTY-ELLLQYD---QLRQEMRRGKCFE 409
            ..:...:           ||.||...  .||...||....| |.|.:.|   .:.::.....||
 Frog   422 ISEAHKV-----------LNSRIDNE--IQRINSLSPDSIYEERLTELDFKINITEKNAEEHCF- 472

  Fly   410 GYTEGEIKFRPTYKYDPGTDNYDSSEKQRAPAYCDRVLWK----------GTRIEQLAYN----- 459
             |.|..::...|      |::.:..:........:.|:|.          .:.:...|::
 Frog   473 -YIEETLRGLIT------TNSNEMKDLDTRLQKMEDVVWDIVNASSPDVVHSSVGSTAHHGPGSV 530

  Fly   460 ------SIMEIRQSDHKPVYAVFQVKVKTRDEVKYKRVQEE-----VLKAVDKRENDNQPQINVE 513
                  .|.:::.:.|:....:|.:.....|...:....:|     :||:::...|:....|.:.
 Frog   531 SGHLVTEIRDLKDAVHQLEGQMFSILHTNVDYSNHNDGHKENDNFILLKSLNDTINEKFDLIQLN 595

  Fly   514 KTVIDFGTVR------------FNEPSTRDFN-------VYNNCPLPVDFSFKEKDIHAICEPWL 559
            |..|:  |||            :.|    |.|       ::||..|.:..:.|.      .|..|
 Frog   596 KVGIE--TVRGDLHKLNHKLNSYEE----DVNLLKDGVSLFNNQILDIKATVKN------TESGL 648

  Fly   560 HVDPRQ-DSLLIDSARSIRLKMNANVRTIAGLLRKI----------------------RASDNFD 601
            |....: :.|..|::.|.     ||....:||..|.                      :...|.|
 Frog   649 HKKVGEVERLCKDTSYSA-----ANNECCSGLQSKFELLSSEITADKGTCTKHTQGIQKEMSNVD 708

  Fly   602 ILILHVENGRDIFITVTGDYQPSCFGLS 629
            ..:..:||......|::|..|....||:
 Frog   709 ARLSKLENVCGKLDTISGSMQRIKDGLN 736

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ocrl	NP_569962.2	INPP5B_PH	23..160	CDD:465268	20/95 (21%)
		INPP5c_INPP5B	185..478	CDD:197327	58/331 (18%)
		RhoGAP_OCRL1	614..823	CDD:239845	5/16 (31%)
emilin2	XP_012820783.1	EMI	50..120	CDD:462204
		235kDa-fam	<169..>794	CDD:130673	116/657 (18%)
		Glutenin_hmw	<786..>1010	CDD:367362
		PRK10263	<789..>892	CDD:236669
		C1q	1022..1158	CDD:420072