Protein Alignment Ocrl and inpp5ka

DIOPT Version :10

• Sequence 1: NP_569962.2
• Gene: Ocrl / 31157
• FlyBaseID: FBgn0023508
• Length: 850
• Species: Drosophila melanogaster
• Sequence 2: XP_009290059.1
• Gene: inpp5ka / 100037338
• ZFINID: ZDB-GENE-070410-101
• Length: 546
• Species: Danio rerio
• Alignment Length: 586
• Identity: 142/586 - (24%)
• Similarity: 224/586 - (38%)
• Gaps: 164/586 - (27%)

  Fly    97 RQDSKSSITTQQFDLSTAEDGPIKYYYYATESHHYEEFVAKVISFKSTM-AQHDPETVLNFRWLN 160
            |.||.:|.:||.                .:...|..:.:|.:::....: ..|..:|
Zfish    20 RSDSAASSSTQS----------------TSSRQHVRQRLAMLLTCVDDLDTDHKLQT-------- 60

  Fly   161 DYRQIGEVKQELKKRESEYIVYKDII---------IYCATWNVNNKTCSDSNNPLRAWLACSEKP 216
                     |..|..:..::|.:.|.         :|..||||......|..|.|..  ..|.|.
Zfish    61 ---------QVAKTLDEAFLVCRQIAGRPKKNPFRLYVVTWNVATAEPPDDVNALLQ--LNSPKK 114

  Fly   217 PDIYAIGLQELDTPTKAMLNSTQVQAIEKQWIDKMMDSVHPDVEYEILMSHRLVATMLTVIVRKQ 281
            ||:|.|||||:   ..|.|......|.|..|....||::.| :.|..:.|.|:...:|....:
Zfish   115 PDLYVIGLQEV---RAAPLKFVSDLAFEDSWSHLFMDTLSP-LHYIKVSSIRMQGLLLLFFSK-- 173

  Fly   282 LRQHIIRCRPKSVA---RGIFNTLGNKGGVAISLQLNEGNICFVNSHLAAHMGYVEERNQDYNAI 343
             .:|:...|...|.   .|::...||||||.|.|......:||:|.||.|||.|..:|..::..|
Zfish   174 -LEHVPFIRDIQVTYTRTGLYGYWGNKGGVTIRLSFYGHMLCFLNCHLTAHMNYASQRVDEFEHI 237

  Fly   344 VEGIRFDDGRT--ISDHDHIFWVGDLNYRIQEPPGQQRPGPLSDAQTYELLLQYDQLRQEMRRGK 406
            ::...|:...|  :.||..:||.||||:|| |..|.........:|.:.||...|||....::..
Zfish   238 LDAQNFNTKNTPHVLDHKVVFWFGDLNFRI-EDHGMLFVRNCITSQRFNLLWPKDQLTMMKQKEV 301

  Fly   407 CFEGYTEGEIKFRPTYKYDPGTDNYDS---------SEKQRAPAYCDRVLWK------------- 449
            ..:.:.||.:.|:||||:|..:||||:         :.|:|.||:|||:||:
Zfish   302 ILQKFEEGPLDFQPTYKFDLNSDNYDTRVQTTWFGFNGKKRKPAWCDRILWRVKPKASLTENTNE 366

  Fly   450 ---------------GTRIEQLAYNSIMEIRQSDHKPVYAVFQVKVKTRDE-------------- 485
                           ..::.|..|.|.||...||||||..:|:::::...|
Zfish   367 EEPEKQQEEEREDEFPLKMTQEYYTSKMEYGISDHKPVIGIFRLELRKMYETPLVQVFAEGEWSA 431

  Fly   486 -----VKYKRVQEEVLKAVDKRENDNQPQINVE----KTVIDFGT--------VRFNEPSTRDFN 533
                 :.|:.:|.....|.|        .|.:.    |:|.|:.|        |.|||..   |.
Zfish   432 DFDAVITYRLLQAFASSAWD--------WIGLYKVGFKSVSDYITYAWVKDDQVSFNEEL---FQ 485

  Fly   534 VYNNCPLPVDFSFKEKDIHAICEPWLHVDPRQDSLLIDSARSIRLKMNANVRTIAGLLRKIRASD 598
            ||.|                           :|.:.:.....:....::|::.|.|:.:..:..:
Zfish   486 VYMN---------------------------KDEIPVLGGECVLCYYSSNLQCIVGISQPFKVQE 523

  Fly   599 N 599
            :
Zfish   524 S 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ocrl	NP_569962.2	INPP5B_PH	23..160	CDD:465268	10/63 (16%)
		INPP5c_INPP5B	185..478	CDD:197327	107/343 (31%)
		RhoGAP_OCRL1	614..823	CDD:239845
inpp5ka	XP_009290059.1	INPP5c_INPP5J-like	85..410	CDD:197328	106/334 (32%)
		SKICH	421..521	CDD:465482	21/137 (15%)