Protein Alignment eIF2Bepsilon and AT2G34970

DIOPT Version :9

• Sequence 1: NP_569961.2
• Gene: eIF2Bepsilon / 31156
• FlyBaseID: FBgn0023512
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_181042.1
• Gene: AT2G34970 / 818061
• AraportID: AT2G34970
• Length: 730
• Species: Arabidopsis thaliana
• Alignment Length: 737
• Identity: 201/737 - (27%)
• Similarity: 357/737 - (48%)
• Gaps: 113/737 - (15%)

  Fly     9 VQAVLIADNNVWNFKPLSDEGSTALLPLVNVRMLDYALMALNRSGVEEVFVYTSLYRSSIREHIR 73
            :||:|:||:....|:|::.|....|||:|||.|:||.|..|..:|:|||||:...:...:.|::.
plant    25 LQAILLADSFATKFRPVTLERPKVLLPIVNVPMIDYTLAWLESAGIEEVFVFCCAHSMQVIEYLE 89

  Fly    74 AGIATDAAWSF--KMTVHVIGGEGCRCFGDAMRDL----DNKALIRGHFILLGADTVTNADLRPV 132
                 .:.|..  .:.|..|........|||:|.:    ...:.|:|.|:|:..|||:|..|..:
plant    90 -----KSEWYSHPNLLVRTIESHKSISAGDALRYMYEQQTETSQIQGDFVLVSGDTVSNMPLADL 149

  Fly   133 LEQHKRQAKFDKGTAATLVFKECANNVRT------GNEVLIAVDRRNDRLHYHQRLRMHHKENRY 191
            :::|:.:.|.|:....|:|.|:..::..|      .:::.||||....:|.:::..::.|.....
plant   150 IQEHRERKKKDEKAIMTMVIKQSKSSPLTHQSRLGTDQLFIAVDPLTKQLLHYEEDKIDHPSGSV 214

  Fly   192 QLPLDVFLGNSCVALHHNLLDPQIAIGSPSMLSLFNDNFDFQ-TRDDFVRGLLINEELLDSRIYV 255
            .|...:...|..|.:.:::.|..|.|.||.:||||.||||:| .|..||:|:|: ::::..:|:.
plant   215 CLEKSLLDTNPSVLVCNDMQDCYIDICSPEVLSLFEDNFDYQHLRRHFVKGVLV-DDIMGYKIFT 278

  Fly   256 ALLPAAQYAHKVNNWPAYQLVSRDIINRWAYPFVPDIGL-----YKLQQEYVFHKDNIYKSPEAH 315
            ..:.:: ||.:::|:.:|..||:|||.||.||:||||..     .||.::.::...::.:|..|.
plant   279 HEIHSS-YAGRIDNFRSYDTVSKDIIQRWTYPYVPDINFSGNRPLKLGRQGIYKASDVVQSRSAD 342

  Fly   316 VSKVALLQNVVIEAGSHVDSGSVISDSVIGANCRIGKNCRLTNAFLMADVTVMDNCRLEHCVVGE 380
            |.     .:.||..|:.:..|..|.:||||..|.||.|..:..:::..:||:.|.|.:.:.:|.:
plant   343 VG-----ASTVIGYGTKIGHGDKIMNSVIGNGCSIGSNVVIEGSYIWNNVTIEDGCEIRNAIVCD 402

  Fly   381 ------GAIINEDCDVSAGCVLGAKSVLPAKKTLAKTLITRTPSRRRSDDE-------------- 425
                  ||::.....:|...|:|...|:||   .:|..:.:.|:...||:|
plant   403 GVKIRAGAVLQPGVVLSFNVVVGRDFVVPA---YSKVSLLQQPTTEDSDEELEYADSSSGTADHL 464

  Fly   426 ----VVVELKS--IGPH-AYIVSDLTTGDPEDSECEDLLPQQPLSIPKMGDLLAPLDEISYCSDF 483
                :.:|.|:  :||. |..:.::..|..::.....:.|     |||        |::|..:..
plant   465 SGLNLQMESKASELGPDGAGYIWEVCEGAHDEEWKHSVAP-----IPK--------DKLSEITQA 516

  Fly   484 SEDDEDASRAVTPLP------------------DDTNIFLGEVIDSLTRGFREKSNPDFLVLEIN 530
            .:||:....:|.|..                  ||...|..||..::.|...|....|.:.:|||
plant   517 IDDDDTDDESVVPTSGELKSDADSINTDVNDPNDDYYYFEKEVEGTVLRAVEENIKVDLVTMEIN 581

  Fly   531 SSRYAYNMSLKE----VNFNVVKAVFGMQSIVEPANDNVLVAINAA-----FKQLGPVVSNYIKS 586
            ..|.::||...:    ..|:::|.     ::..|.|....:..|||     :|.|   :..|.|.
plant   582 GLRLSFNMESADCAGATFFSMIKL-----ALDTPHNSGSELYKNAASIITKWKDL---LGFYAKK 638

  Fly   587 EDSMMDCLKALEDVYEENHLVRGKI-SQIVHYLYDKDFVSESAIQAW---YAQLDEEEHAHLRQS 647
            .|..::.:...|::.:|:|...|.: :||:|.|||||.:.|.||..|   .|..||.:..:|:|
plant   639 IDEQIEVIMKFEEMCQESHKELGPLFTQILHLLYDKDVLQEDAILRWEEEKAGADEADKVYLKQ- 702

  Fly   648 LAKLVAWLDQSSEEDDDEEDDD 669
            ....:.||.::|||:|::::|:
plant   703 CDTFIQWLKEASEEEDEDDEDE 724

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Bepsilon	NP_569961.2	eIF-2B_epsilon_N	9..223	CDD:133040	63/225 (28%)
		GCD1	22..409	CDD:224129	121/410 (30%)
		LbetaH	326..397	CDD:294107	22/76 (29%)
		W2_eIF2B_epsilon	499..659	CDD:211396	49/172 (28%)
AT2G34970	NP_181042.1	eIF-2B_epsilon_N	25..246	CDD:133040	63/225 (28%)
		GCD1	26..425	CDD:224129	122/410 (30%)
		LbH_eIF2B_epsilon	348..426	CDD:100061	22/77 (29%)
		W2_eIF2B_epsilon	550..714	CDD:211396	49/172 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	86	1.000	Domainoid score	I2784
eggNOG	1	0.900	-	-		E1_COG1208
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2903
Inparanoid	1	1.050	255	1.000	Inparanoid score	I1005
OMA	1	1.010	-	-		QHG54474
OrthoDB	1	1.010	-	-		D369837at2759
OrthoFinder	1	1.000	-	-		FOG0003779
OrthoInspector	1	1.000	-	-		otm2874
orthoMCL	1	0.900	-	-		OOG6_101778
Panther	1	1.100	-	-	LDO	PTHR45887
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2634
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840