Protein Alignment eIF2Bepsilon and gmppab

DIOPT Version :9

• Sequence 1: NP_569961.2
• Gene: eIF2Bepsilon / 31156
• FlyBaseID: FBgn0023512
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_956791.1
• Gene: gmppab / 393469
• ZFINID: ZDB-GENE-040426-1550
• Length: 422
• Species: Danio rerio
• Alignment Length: 455
• Identity: 88/455 - (19%)
• Similarity: 165/455 - (36%)
• Gaps: 131/455 - (28%)

  Fly    22 FKPLSDEGSTALLPLVNVRMLDYALMA---------------------LNRSGVEEVFVYTSLYR 65
            |:|||.|....|.|:..|.||.:.:.|                     |||      |:|:
Zfish    17 FRPLSFEVPKPLFPVAGVPMLQHHIEACAQVPDMKEIMLIGFYQPNDELNR------FIYS---- 71

  Fly    66 SSIREHIRAGIATDAAWSFKMTVHVIGGEGCRCFGDAMRDLDNKALIRG--HFILLGADTVTNAD 128
                          |...||:.:..:........|..:....::.|..|  .|.|:.||..:...
Zfish    72 --------------AQQEFKIPIRYLQEFAALGTGGGIYHFRDQILSGGPAAFFLMNADVCSEFP 122

  Fly   129 LRPVLEQHKRQAKFDKGTAATLVFKECANNVRTGNEVLIAVDRR-NDRLHYHQRLRMHHKENRYQ 192
            |..:|:.|::..:...|    ::....||..::.|...|..:.. |:.||:.::
Zfish   123 LLEMLQFHRQHGENHCG----VLLGTTANRTQSLNYGCIVENHETNEVLHFVEK----------- 172

  Fly   193 LPLDVFLGNSCVALHHNLLDPQIAIGSPSMLS----LFNDNFDFQTRDDFVRGLLINEEL-LDSR 252
             | ..|:.        ::::..|.:.:|.:.:    :|..|...:.:::...|..:.|.: |:..
Zfish   173 -P-STFVS--------DIINCGIYLFTPDIFAHIGKVFQRNQQEKIQEELTHGRQMPEVVRLEQD 227

  Fly   253 IYVALLPAAQ---YAHKVNN-WPAYQLVSRDIINRWAYPFVPDIGLYKLQQEYVFHKDNIYKSPE 313
            |:.||  |.|   :.:|..: |...:.....|.....|          |:|.:..|.:.: .:.:
Zfish   228 IFTAL--AGQKKLFVYKTQHFWSQIKSAGSAIYASRLY----------LKQYHQTHPERL-ATNQ 279

  Fly   314 AHVSKVALLQNVVIEAGSHVDSGSVISDSVIGANCRIGKNCRLTNAFLMADVTVMDNCRLEHCVV 378
            ....|:.  .:|.|...:::|     ..:|:|.|..|||.           ||:....|:...::
Zfish   280 GGTPKIT--GDVYIHPTANID-----PSAVLGPNVSIGKG-----------VTIGGGVRVRESII 326

  Fly   379 GEGAIINEDCDVSAGCVLGAKSVLPAKKTLAK-TLITRTPSRRRSDDEVVVELKSIGPHAYIVSD 442
            ..||::.:.|     |||  .|::....|:.| ..:..|||....:|          |:|.|.|:
Zfish   327 LHGAVLQDHC-----CVL--NSIVGWDSTVGKWARVEGTPSDPNPND----------PYAKIDSE 374

  Fly   443  442
            Zfish   375  374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Bepsilon	NP_569961.2	eIF-2B_epsilon_N	9..223	CDD:133040	41/224 (18%)
		GCD1	22..409	CDD:224129	79/419 (19%)
		LbetaH	326..397	CDD:294107	16/70 (23%)
		W2_eIF2B_epsilon	499..659	CDD:211396
gmppab	NP_956791.1	GCD1	1..351	CDD:224129	79/420 (19%)
		M1P_guanylylT_A_like_N	4..263	CDD:133050	54/296 (18%)
		LbetaH	291..357	CDD:294107	20/88 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810