Protein Alignment eIF2Bepsilon and CG8207

DIOPT Version :9

• Sequence 1: NP_569961.2
• Gene: eIF2Bepsilon / 31156
• FlyBaseID: FBgn0023512
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_611051.2
• Gene: CG8207 / 36730
• FlyBaseID: FBgn0034035
• Length: 438
• Species: Drosophila melanogaster
• Alignment Length: 503
• Identity: 92/503 - (18%)
• Similarity: 160/503 - (31%)
• Gaps: 177/503 - (35%)

  Fly    22 FKPLSDEGSTALLPLVNVRMLDYALMALNR-SGVEEVFV---------------YTSLYRSS--- 67
            |:|||.:....|.||....::.:.:.|..: ..:.|:.:               ..:||.||
  Fly    17 FRPLSLDTPKPLFPLAGRPLIAHHIEACAQLPDIREILIIGYYPQTQMEGFVGDMQALYSSSNIN 81

  Fly    68 ---IREHIRAGIATDAAWSFKMTVHVIGGEGCRCFGDAMRDLDNKALIRGHFILLGADTVTNADL 129
               ::|....|.|                .|...|.|.:|..:.:|     |.:|..|...:..|
  Fly    82 IRYLQEFTALGTA----------------GGMYHFRDQIRAGNPRA-----FFVLNGDVCADFPL 125

  Fly   130 RPVLEQHKRQAKFDKGTAATLVFKECANNVRTGNEVLIAVDRRNDRLHY-------HQRLRMHHK 187
            :.:.:.|      :|..|:.||            .::.....|...|||       ......|:.
  Fly   126 QELCDFH------EKRPASALV------------TIMSTEATRQQSLHYGCLVFDRSSGAVSHYV 172

  Fly   188 ENR------------YQLPLDVFLGNSCVALHHNLLDPQIAIGSPSMLSLF-NDNFDFQTRDDFV 239
            |..            |...:|:|  .....:.|:.       |.......| |.|.:...|:
  Fly   173 EKPSSYVSTFINCGVYVCSMDIF--TVLAQIFHSR-------GQEYSCQAFCNGNGNGNGRE--- 225

  Fly   240 RGLLINEELLDSRIYVALLPAA----QYAHKVNNWPAYQLVSRDIINRWAYPFVPDIGLYKLQQE 300
            :|.:..|:       ..|.|.|    .:|..|.||             |:........:|..:
  Fly   226 QGHIKWEQ-------EVLTPLAGTDKLFAMPVPNW-------------WSQLKTAGSAIYANR-- 268

  Fly   301 YVFHKDNIYKSPEAHVSKVALLQNVVIEAGS---------HVD-----SGSVISDSVIGAN---- 347
               |...:||  :.|..::|   ||.|:.|.         |.|     |.:|...:|:|.|
  Fly   269 ---HYLGLYK--KTHPERLA---NVGIKRGEGDGSLICTVHPDVYVHPSATVHHSAVLGPNVAIG 325

  Fly   348 --CRIGKNCRLTNAFLMADVTVMDNCRLEHCVVGEGAII-------------------------- 384
              ..||...|:..:.::....::|:..:.|.:||.|:.|
  Fly   326 PGVTIGPGVRIRESIVLEQAQILDHTLVLHSIVGRGSTIGAWARVEGTPSDPDPNKPFAKMENPP 390

  Fly   385 ---NEDCDVSAGCVLGAKSVLPAKKTLAKTLITRTPSRRRS-DDEVVV 428
               ||.....:..:||....:||:|.|..:::.......|| .:|:::
  Fly   391 LFNNEGKLNPSITILGCFVQVPAEKILLNSIVLPHKELSRSFKNEIIL 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Bepsilon	NP_569961.2	eIF-2B_epsilon_N	9..223	CDD:133040	41/241 (17%)
		GCD1	22..409	CDD:224129	88/481 (18%)
		LbetaH	326..397	CDD:294107	20/119 (17%)
		W2_eIF2B_epsilon	499..659	CDD:211396
CG8207	NP_611051.2	GCD1	1..366	CDD:224129	81/429 (19%)
		M1P_guanylylT_A_like_N	4..270	CDD:133050	56/328 (17%)
		LbetaH	306..372	CDD:294107	14/65 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456493
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1208
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740