Protein Alignment eIF2Bepsilon and Gmppb

DIOPT Version :9

• Sequence 1: NP_569961.2
• Gene: eIF2Bepsilon / 31156
• FlyBaseID: FBgn0023512
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001344611.1
• Gene: Gmppb / 331026
• MGIID: 2660880
• Length: 360
• Species: Mus musculus
• Alignment Length: 439
• Identity: 78/439 - (17%)
• Similarity: 157/439 - (35%)
• Gaps: 136/439 - (30%)

  Fly     9 VQAVLIADNNVWNFKPLSDEGSTALLPLVNVRMLDYALMALNRSGVEEVFVYTSLYRSSIREHIR 73
            ::|:::........:||:......|:...|..:|.:.:.||..:||:.|.:..|.....:.:.::
Mouse     1 MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQMLEKEMK 65

  Fly    74 A-----GIATDAAWSFKMTVHVIGGEGCRCFGDAMRDLDNKALIRGHFILLGADTVTNADLRPVL 133
            |     ||..    |.......:|..|.....   |||.::.  ...|.:|.:|.:.:...:.::
Mouse    66 AQEQRLGIRI----SMSHEEEPLGTAGPLALA---RDLLSET--ADPFFVLNSDVICDFPFQAMV 121

  Fly   134 EQHKRQAKFDKGTAATLVFKECANNVRTGNEVLIAVDRRNDRLHYHQRLRMHHKENRYQLPLDVF 198
            :.|:..     |...:::..:.....:.|   ::..:....|:|            |:.....||
Mouse   122 QFHRHH-----GQEGSILVTKVEEPSKYG---VVVCEADTGRIH------------RFVEKPQVF 166

  Fly   199 LGNSCVALHHNLLDPQIAIGSPSMLSLFNDNFDFQTRDDFVRGLLINEELLDSRIYVALLPAAQ- 262
            :.|.        ::..:.|.||::|                :.:.:....::..|:..:....|
Mouse   167 VSNK--------INAGMYILSPAVL----------------QRIQLKPTSIEKEIFPVMAKEGQL 207

  Fly   263 YAHKVNNWPAYQLVSRDIINRWAYPFVPDIG------------LYKLQQEYVFHKDNIYK----- 310
            ||.::..:             |.     |||            |..|:|:   |.:.:|.
Mouse   208 YAMELQGF-------------WM-----DIGQPKDFLTGMCLFLQSLRQK---HPERLYSGPGIV 251

  Fly   311 -----SPEAHVSK-------VALLQNVVIEAG-----------SHVDSGSVISDSVIGANCRIGK 352
                 .|.|.:.:       |:|...||:|.|           :|:.|.|.:...::|..||:|:
Mouse   252 GNVLVDPSARIGQNCSIGPNVSLGPGVVVEDGVCIRRCTVLRDAHIRSHSWLESCIVGWRCRVGQ 316

  Fly   353 NCRLTNAFLMADVTVMDNCRLEHCVVGEGAIINEDCDVSAGCVLGAKSV 401
            ..|:.|      |||:          ||..|:|::..::...||..||:
Mouse   317 WVRMEN------VTVL----------GEDVIVNDELYLNGASVLPHKSI 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Bepsilon	NP_569961.2	eIF-2B_epsilon_N	9..223	CDD:133040	36/218 (17%)
		GCD1	22..409	CDD:224129	77/426 (18%)
		LbetaH	326..397	CDD:294107	20/81 (25%)
		W2_eIF2B_epsilon	499..659	CDD:211396
Gmppb	NP_001344611.1	M1P_guanylylT_B_like_N	1..233	CDD:133047	45/302 (15%)
		LbetaH	255..334	CDD:381831	23/94 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810