DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rbcn-3B and MDV1

DIOPT Version :9

Sequence 1:	NP_001284797.1	Gene:	Rbcn-3B / 31155	FlyBaseID:	FBgn0023510	Length:	1525	Species:	Drosophila melanogaster
Sequence 2:	NP_012423.1	Gene:	MDV1 / 853332	SGDID:	S000003648	Length:	714	Species:	Saccharomyces cerevisiae

Alignment Length:	293	Identity:	75/293 - (25%)
Similarity:	112/293 - (38%)	Gaps:	77/293 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LWGPTAPTHCISSVFLSDDQFTLVTGCYDGQICLWQV--------------EPTTLKMSPRCL-- 60
            |.|..|..:|:.   ::.|..|||||..|..:.||.:              .||....|| |:
Yeast   437 LAGHLATINCMQ---INRDYGTLVTGGRDAALKLWNLNLAQQLYQETQNLTSPTNHIDSP-CVHT 497

  Fly    61 LVGHSAPVLCLVRASLLPENNFLVSSSENGEMCTWDLTDGKCMEAVKLPQVHTQIQSYHTANSED 125
            ...|:..|..|   ||.|  :||||.|::..:..|||..|||::.:.|...:....|.:...|:.
Yeast   498 FEAHTDEVTAL---SLDP--SFLVSGSQDRTIRQWDLRSGKCLQTIDLSFANVLTTSTNVDLSKS 557

  Fly   126 VRLFCIGYYAEIMVMDPFSLEVIYVLSSKVKPDW-ISAIHVLRPMRRKDDVVL------AITTTG 183
            ..|........|..:..|...:.......|...| :.:..|:|.::...|.:.      |...||
Yeast   558 TLLTQRNERPSIGALQSFDAALATGTKDGVVRLWDLRSGKVIRTLKGHTDAITSLKFDSACLVTG 622

  Fly   184 ----TVKVWTL-TGNENK-HA---------------------EP---IYENESKEIRCLNAITMN 218
                ||::|.| ||..|| ||                     ||   ||::|..|       :.:
Yeast   623 SYDRTVRIWDLRTGLLNKFHAYSAPVLSLDLFQENAAVVVADEPSVQIYDSEKDE-------SWS 680

  Fly   219 CCAQ-NQRTVLLVCTKYWQIY-----DAGDFTV 245
            |..| |:.:|..|  ||.:.|     :.||..:
Yeast   681 CVEQGNETSVSTV--KYKENYMVEGRENGDVNI 711

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbcn-3B	NP_001284797.1	WD40	<11..>204	CDD:225201	63/244 (26%)
		WD40 repeat	20..63	CDD:293791	15/58 (26%)
		WD40	<22..202	CDD:295369	57/232 (25%)
		WD40 repeat	68..107	CDD:293791	16/38 (42%)
		WD40 repeat	118..152	CDD:293791	4/33 (12%)
		WD40 repeat	160..204	CDD:293791	20/79 (25%)
		WD40 repeat	212..251	CDD:293791	10/40 (25%)
		WD40 repeat	406..459	CDD:293791
		WD40	<449..>607	CDD:225201
		WD40	453..>597	CDD:295369
		WD40 repeat	513..555	CDD:293791
		WD40 repeat	560..596	CDD:293791
		WD40	<1395..>1469	CDD:225201
		WD40	<1399..1495	CDD:295369
		WD40 repeat	1439..1466	CDD:293791
MDV1	NP_012423.1	Mdv1	123..171	CDD:402923
		WD40	397..713	CDD:238121	75/293 (26%)
		WD40 repeat	402..439	CDD:293791	1/1 (100%)
		WD40 repeat	444..499	CDD:293791	15/58 (26%)
		WD40 repeat	506..539	CDD:293791	15/37 (41%)
		WD40 repeat	546..603	CDD:293791	9/56 (16%)
		WD40 repeat	648..683	CDD:293791	7/41 (17%)
		WD40 repeat	690..712	CDD:293791	7/24 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4155
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900