DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbcn-3B and wds

DIOPT Version :9

Sequence 1:	NP_001284797.1	Gene:	Rbcn-3B / 31155	FlyBaseID:	FBgn0023510	Length:	1525	Species:	Drosophila melanogaster
Sequence 2:	NP_001245503.1	Gene:	wds / 53428	FlyBaseID:	FBgn0040066	Length:	361	Species:	Drosophila melanogaster

Alignment Length:	359	Identity:	79/359 - (22%)
Similarity:	124/359 - (34%)	Gaps:	118/359 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VVLWG-------PTAPTH--CISSVFLSDDQFTLVTGCYDGQICLWQVEP-TTLKMSPRCLLVGH 64
            :.:||       .|...|  .||.|..|.|...||:|..|..:.:|::.. .:||     .|.||
  Fly    96 IKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLK-----TLKGH 155

  Fly    65 SAPVLCLVRASLLPENNFLVSSSENGEMCTWDLTDGKCMEAVKLPQVHTQIQSYHTANSEDVRLF 129
            |..|.|   .:..|::|.:||.|.:..:..||:..|||::.  ||.....:.:.| .|.:...:.
  Fly   156 SNYVFC---CNFNPQSNLIVSGSFDESVRIWDVRTGKCLKT--LPAHSDPVSAVH-FNRDGSLIV 214

  Fly   130 CIGYYAEIMVMDPFSLEVIYVLSSKVKPDWISAIHVLRPMRRKDDVVLAITTTGTVKVW------ 188
            ...|.....:.|..|.:.:..|.....|. :|.:    ........:||.|...|:|:|
  Fly   215 SSSYDGLCRIWDTASGQCLKTLIDDDNPP-VSFV----KFSPNGKYILAATLDNTLKLWDYSKGK 274

  Fly   189 ---TLTGNENKHAEPIYENESKEIRCLNAITMNCCAQNQRTVLLVCTKYWQIYDAGDFTVLCSVI 250
               |.||::|            |..|:.|                           :|:|
  Fly   275 CLKTYTGHKN------------EKYCIFA---------------------------NFSV----- 295

  Fly   251 APARERWQGGDFITSDRVMLWTDEGKGYLYKLPANCIPDNKEFHSKSVVRDAPYLYYVLQHAGDK 315
                   .||.:|.|.     :::...|::.|           .||.||:.       ||...|.
  Fly   296 -------TGGKWIVSG-----SEDNMVYIWNL-----------QSKEVVQK-------LQGHTDT 330

  Fly   316 VL--SCPPAMKLLQGAGGQHNLLRGDSEGYISVW 347
            ||  :|.|...::..|.     |..|..  |.:|
  Fly   331 VLCTACHPTENIIASAA-----LENDKT--IKLW 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbcn-3B	NP_001284797.1	WD40	<11..>204	CDD:225201	52/211 (25%)
		WD40 repeat	20..63	CDD:293791	14/45 (31%)
		WD40	<22..202	CDD:295369	48/189 (25%)
		WD40 repeat	68..107	CDD:293791	12/38 (32%)
		WD40 repeat	118..152	CDD:293791	5/33 (15%)
		WD40 repeat	160..204	CDD:293791	11/52 (21%)
		WD40 repeat	212..251	CDD:293791	3/38 (8%)
		WD40 repeat	406..459	CDD:293791
		WD40	<449..>607	CDD:225201
		WD40	453..>597	CDD:295369
		WD40 repeat	513..555	CDD:293791
		WD40 repeat	560..596	CDD:293791
		WD40	<1395..>1469	CDD:225201
		WD40	<1399..1495	CDD:295369
		WD40 repeat	1439..1466	CDD:293791
wds	NP_001245503.1	WD40	64..358	CDD:238121	79/359 (22%)
		WD40 repeat	75..112	CDD:293791	3/15 (20%)
		WD40 repeat	118..154	CDD:293791	12/40 (30%)
		WD40 repeat	159..195	CDD:293791	12/40 (30%)
		WD40 repeat	202..237	CDD:293791	5/35 (14%)
		WD40 repeat	244..280	CDD:293791	8/39 (21%)
		WD40 repeat	288..325	CDD:293791	14/98 (14%)
		WD40 repeat	331..357	CDD:293791	8/32 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442356
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930