DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbcn-3B and Lis-1

DIOPT Version :9

Sequence 1:	NP_001284797.1	Gene:	Rbcn-3B / 31155	FlyBaseID:	FBgn0023510	Length:	1525	Species:	Drosophila melanogaster
Sequence 2:	NP_001246361.1	Gene:	Lis-1 / 36791	FlyBaseID:	FBgn0015754	Length:	411	Species:	Drosophila melanogaster

Alignment Length:	158	Identity:	30/158 - (18%)
Similarity:	65/158 - (41%)	Gaps:	17/158 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   445 KQNFSDW----PSHQILYGHRGRVNCLLCPSMIHSRYEKSHLLSGGIDFAVCLWDLYSGSLLHRF 505
            |:...:|    |....|.|||..:..::    .|..:  :.::|...|..:.:||..:|......
  Fly    88 KRTPGEWIPRPPEKFSLTGHRASITRVI----FHPIF--ALMVSASEDATIRIWDFETGEYERSL 146

  Fly   506 CVHAGEITQLLVPPESCSPRILKCICSVASDHSVTLVSLQER-KCVTLASRHLFPVVTIKWRPLD 569
            ..|...:..:....:.      |.:.|.::|.|:.|...|:. :|:.....|...|.::.:.|..
  Fly   147 KGHTDSVQDVAFDAQG------KLLASCSADLSIKLWDFQQSYECIKTMHGHDHNVSSVAFVPAG 205

  Fly   570 DFLIVGCSDGSVYVWQMETGHLDRVLHG 597
            |:::....|.::.:|::.||:..:...|
  Fly   206 DYVLSASRDRTIKMWEVATGYCVKTYTG 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbcn-3B	NP_001284797.1	WD40	<11..>204	CDD:225201
		WD40 repeat	20..63	CDD:293791
		WD40	<22..202	CDD:295369
		WD40 repeat	68..107	CDD:293791
		WD40 repeat	118..152	CDD:293791
		WD40 repeat	160..204	CDD:293791
		WD40 repeat	212..251	CDD:293791
		WD40 repeat	406..459	CDD:293791	4/17 (24%)
		WD40	<449..>607	CDD:225201	29/154 (19%)
		WD40	453..>597	CDD:295369	26/144 (18%)
		WD40 repeat	513..555	CDD:293791	7/42 (17%)
		WD40 repeat	560..596	CDD:293791	7/35 (20%)
		WD40	<1395..>1469	CDD:225201
		WD40	<1399..1495	CDD:295369
		WD40 repeat	1439..1466	CDD:293791
Lis-1	NP_001246361.1	LisH	9..40	CDD:128913
		WD40	100..409	CDD:238121	27/146 (18%)
		WD40 repeat	111..148	CDD:293791	6/42 (14%)
		WD40 repeat	154..191	CDD:293791	7/42 (17%)
		WD40 repeat	196..232	CDD:293791	7/35 (20%)
		WD40 repeat	239..274	CDD:293791
		WD40 repeat	280..336	CDD:293791
		WD40 repeat	342..378	CDD:293791
		WD40 repeat	384..408	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442362
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930