DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbcn-3B and LOC100332173

DIOPT Version :9

Sequence 1:	NP_001284797.1	Gene:	Rbcn-3B / 31155	FlyBaseID:	FBgn0023510	Length:	1525	Species:	Drosophila melanogaster
Sequence 2:	XP_002667373.4	Gene:	LOC100332173 / 100332173	-ID:	-	Length:	276	Species:	Danio rerio

Alignment Length:	280	Identity:	135/280 - (48%)
Similarity:	195/280 - (69%)	Gaps:	16/280 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly  1258 LDVSKVLLGLLEISCEG-KAVPNLNYKLPLTPQADACRTARHALRLIATARPAAFITTMAREVAR 1321
            :|||.||:||||:..:. |.:.|::..|||:|.||:.|:|||||.|||||||.|||||:||||.|
Zfish     1 MDVSAVLMGLLELCADAEKQLSNISMGLPLSPAADSARSARHALSLIATARPPAFITTIAREVHR 65

  Fly  1322 YNTMQ----QNAQSINTPLTQSVLHKAKGEILQCVEMLIDKMQSEIAGLLVEVMDIALHCVDGNE 1382
            :..||    |:.|:|:|    :.|.:||.|||:.:|:||:||.|::..||||||||.::|::|:.
Zfish    66 HTAMQSQGSQSQQNIHT----TTLARAKTEILRVIEILIEKMPSDVVDLLVEVMDIIMYCIEGSL 126

  Fly  1383 LKNRGLAELCPAICKFNQISHCAQTRRIAVGANSGNLAIYELRQNKCQMIPAHTHPITSLAFSPD 1447
            :|.:||:|..||||:|..:::|.::.||||||..|::|:|::|..|||.|..|..|||:::|:||
Zfish   127 VKKKGLSECFPAICRFYMVAYCERSYRIAVGARQGSVALYDVRTGKCQHIHGHKGPITAVSFAPD 191

  Fly  1448 GKYLVSYSCAENRLSFWQTSTGMFG-LGQ----SQTRCTKGYSTAPIPDVS--RLNPMRLAKLVW 1505
            |:||.:||.|::.:||||.:|.:.| :|.    .|.||.|.|...|:...|  ..|.::||:|:|
Zfish   192 GRYLATYSNADSHISFWQMNTSLLGSIGMLNSAPQLRCIKTYQVPPVQPASPGSQNALKLARLIW 256

  Fly  1506 INNRTVTLMLADGSETRFNV 1525
            .:||.|.||..||.|.||.|
Zfish   257 TSNRNVILMAHDGKEHRFMV 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbcn-3B	NP_001284797.1	WD40	<11..>204	CDD:225201
		WD40 repeat	20..63	CDD:293791
		WD40	<22..202	CDD:295369
		WD40 repeat	68..107	CDD:293791
		WD40 repeat	118..152	CDD:293791
		WD40 repeat	160..204	CDD:293791
		WD40 repeat	212..251	CDD:293791
		WD40 repeat	406..459	CDD:293791
		WD40	<449..>607	CDD:225201
		WD40	453..>597	CDD:295369
		WD40 repeat	513..555	CDD:293791
		WD40 repeat	560..596	CDD:293791
		WD40	<1395..>1469	CDD:225201	35/73 (48%)
		WD40	<1399..1495	CDD:295369	42/102 (41%)
		WD40 repeat	1439..1466	CDD:293791	14/26 (54%)
LOC100332173	XP_002667373.4	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I12154
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D331603at33208
OrthoFinder	1	1.000	-	-		FOG0002541
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104321
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820