Protein Alignment Edem1 and MNS1

DIOPT Version :10

• Sequence 1: NP_001259152.1
• Gene: Edem1 / 31154
• FlyBaseID: FBgn0023511
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_012665.3
• Gene: MNS1 / 853595
• SGDID: S000003892
• Length: 549
• Species: Saccharomyces cerevisiae
• Alignment Length: 554
• Identity: 142/554 - (25%)
• Similarity: 232/554 - (41%)
• Gaps: 133/554 - (24%)

  Fly    40 ELREDVRRMFQHAYDGYLRHASNYDELRPLTCDGHDT--------WGSYSLTLIDALDTLATMGN 96
            |:|:.:..||..::..|.:|...||...|:....|:.        |     .::|::|||..|.|
Yeast    37 EMRDRIESMFLESWRDYSKHGWGYDVYGPIEHTSHNMPRGNQPLGW-----IIVDSVDTLMLMYN 96

  Fly    97 FT---------EFRRAARLLEEKMDFDRDINVSVFETNIRIVGGLLSAHLLSKRAGVELEPGWPC 152
            .:         |.:|:...:.:.:|||.|..|:||||.||::||||||:.||.    .||.|  .
Yeast    97 SSTLYKSEFEAEIQRSEHWINDVLDFDIDAEVNVFETTIRMLGGLLSAYHLSD----VLEVG--N 155

  Fly   153 KGPLLRLAEDVARRLLPAFV-TNTGMPYGTVNLRYGVP---KGETSITCTAGVGTFLIEFGTLSR 213
            |...|..|.|:..||..||: |.||:||.::||..|..   ..:...:.||...|..:||..|:.
Yeast   156 KTVYLNKAIDLGDRLALAFLSTQTGIPYSSINLHSGQAVKNHADGGASSTAEFTTLQMEFKYLAY 220

  Fly   214 LTGKTIYEDVAMKAVHALWAYRSPIGLFGNHIDV----QSGRWTALDSGIGAGVDSLFEYLVKAS 274
            |||...|.::..:....|:.....:..:...:.:    .:|::.|.....|:..||.:|||:|..
Yeast   221 LTGNRTYWELVERVYEPLYKNNDLLNTYDGLVPIYTFPDTGKFGASTIRFGSRGDSFYEYLLKQY 285

  Fly   275 VLLNRPELLELFHEARAAIDKYMRKED-----WYVW---VGMNKGRVTLPVFQSLEAFWPGILSI 331
            :|.:.....:|:.::...:.|::..:.     ||:.   .|:: |::: |....|..|..|:|:
Yeast   286 LLTHETLYYDLYRKSMEGMKKHLLAQSKPSSLWYIGEREQGLH-GQLS-PKMDHLVCFMGGLLA- 347

  Fly   332 IGDTE----------PALRTISRYIGVW----------------KKYGFLPE------------- 357
            .|.||          |...........|                ...|..||
Yeast   348 SGSTEGLSIHEARRRPFFSLSLERKSDWDLAKGITDTCYQMYKQSSSGLAPEIVVFNDGNIKQDG 412

  Fly   358 FYNIAAGEASPNREVYPL------RPELIESAMYLYRATGNEYLLEFGEHMLETLEFSAKTKCG- 415
            ::..:.|:..    |.||      |||.:||.|::|..:.:....|:|..:..:...:....|.
Yeast   413 WWRSSVGDFF----VKPLDRHNLQRPETVESIMFMYHLSHDHKYREWGAEIATSFFENTCVDCND 473

  Fly   416 -----YATIRNVVT--HEKENRMESFFLAETSKYLYLLFDEENFLHNDGSGGELLSTEDDVCVVQ 473
                 :.::.:.:|  .:|.|.||||:||||.||||:||.:                |.|:..|
Yeast   474 PKLRRFTSLSDCITLPTKKSNNMESFWLAETLKYLYILFLD----------------EFDLTKV- 521

  Fly   474 AGAYIFNTEAHPMDMSALHCCHAHNEDIYTSLDL 507
                :|||||||..:.        :|:|..|..|
Yeast   522 ----VFNTEAHPFPVL--------DEEILKSQSL 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Edem1	NP_001259152.1	Glyco_hydro_47	48..486	CDD:460241	135/523 (26%)
MNS1	NP_012665.3	Glyco_hydro_47	45..532	CDD:460241	136/525 (26%)