DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Edem1 and AT1G27520

DIOPT Version :9

Sequence 1:	NP_001259152.1	Gene:	Edem1 / 31154	FlyBaseID:	FBgn0023511	Length:	1004	Species:	Drosophila melanogaster
Sequence 2:	NP_564288.1	Gene:	AT1G27520 / 839643	AraportID:	AT1G27520	Length:	574	Species:	Arabidopsis thaliana

Alignment Length:	586	Identity:	218/586 - (37%)
Similarity:	309/586 - (52%)	Gaps:	63/586 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 YPGTLICAVLLVLLSTGVSGQKQYSKARKLELREDVRRMFQHAYDGYLRHASNYDELRPLTCDGH 74
            :|..|...:|:.|....|....|:.:.:|.::||.||.||.||||.|:.:|..:|||:|||....
plant     6 HPRRLFLCLLISLTFFVVDPSSQHIEVKKKQMREKVREMFYHAYDNYMTYAFPHDELKPLTKSFT 70

  Fly    75 DT---------------WGSYSLTLIDALDTLATMGNFTEFRRAARLLEEKMDFDRDINVSVFET 124
            |:               :...::||:::|.:||.:||.|||.:....|.|.:.||.|..|::||.
plant    71 DSLSELGNLKLEHLPTDYNGSAVTLVESLSSLAILGNSTEFEKGVLWLSENLTFDIDARVNLFEC 135

  Fly   125 NIRIVGGLLSAHLLSKRAGVELEPGWPCKGPLLRLAEDVARRLLPAFVTNTGMPYGTVNLRYGVP 189
            |||::|||:|||||:......|..| .....|||||||:.:|.||||.|.||:||..:||:.||.
plant   136 NIRVLGGLISAHLLAIDPNNRLIQG-SYNNQLLRLAEDLGKRFLPAFETPTGLPYAWINLKNGVM 199

  Fly   190 KGETSITCTAGVGTFLIEFGTLSRLTGKTIYEDVAMKAVHALWAYRSPIGLFGNHIDVQSGRWTA 254
            :.||:.|.|:|.|:.::|.|.||||||...:|..|::|:..||..||.:.|.|..:||.:|.|..
plant   200 ENETTETSTSGCGSLVLEMGALSRLTGDPRFESAALRALRQLWRMRSSLDLLGTTLDVVTGEWIE 264

  Fly   255 LDSGIGAGVDSLFEYLVKASVLLNRPELLELFHEARAAIDKYMRKEDWYVWVGMNKGRVTLPVFQ 319
            ..|.|||||||.:|||:||.:|..:.:...:||.|..|..||.|...||....|..|:.|.....
plant   265 YSSSIGAGVDSFYEYLLKAYILFGKEDYWRMFHSAYLASQKYFRHGPWYHEANMWSGKPTYWQLT 329

  Fly   320 SLEAFWPGILSIIGDTEPALRTISRYIGVWKKYGFLPEFYNIAAGEASPNREVYPLRPELIESAM 384
            ||:|||||:..::||...|..:...:..||:|:|.|||.|.:......|..:.|||||||.||..
plant   330 SLQAFWPGLQVLVGDIAAANSSHREFFHVWEKFGVLPERYLLDHQIIHPTMKYYPLRPELAESTF 394

  Fly   385 YLYRATGNEYLLEFGEHMLETLEFSAKTKCGYATIRNVVTHEKENRMESFFLAETSKYLYLLFDE 449
            |||:||.:.:.|:.||.|:::|....|...|:|::|:|.|.:.|:...|||||||.||||||||:
plant   395 YLYQATKDPWYLDVGESMVKSLNLYTKVPGGFASVRDVTTMQLEDHQHSFFLAETCKYLYLLFDD 459

  Fly   450 ENFLHNDGSGGELLSTEDDVCVVQAGAYIFNTEAHPMDMSALHCCHAHNEDIYTSLDLQRFSPRA 514
            .                    .|....|||.||.||:.:  :...|....:.|       ||...
plant   460 S--------------------FVAKRNYIFTTEGHPIQV--VSSWHEKLPETY-------FSGNW 495

  Fly   515 ILERS---KKRQVAVQEQWVP-----QCHPENNEFFNKEDES----VQAQDSEKEQEREQSGTST 567
            .|.:|   :.|..|:..|..|     ..|||      ::.||    :..|.:.|....::.|...
plant   496 TLSKSGAWESRASALSLQVCPLISLNSRHPE------QQRESACHVLDEQINHKCWSNKECGVDA 554

  Fly   568 T 568
            |
plant   555 T 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Edem1	NP_001259152.1	Glyco_hydro_47	48..486	CDD:279825	187/452 (41%)
AT1G27520	NP_564288.1	Glyco_hydro_47	44..476	CDD:366693	187/452 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2429
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D434316at2759
OrthoFinder	1	1.000	-	-		FOG0000713
OrthoInspector	1	1.000	-	-		otm3502
orthoMCL	1	0.900	-	-		OOG6_101442
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.720