Protein Alignment Edem1 and man1a1

DIOPT Version :10

• Sequence 1: NP_001259152.1
• Gene: Edem1 / 31154
• FlyBaseID: FBgn0023511
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: XP_694435.2
• Gene: man1a1 / 566078
• ZFINID: ZDB-GENE-041014-321
• Length: 618
• Species: Danio rerio
• Alignment Length: 485
• Identity: 156/485 - (32%)
• Similarity: 253/485 - (52%)
• Gaps: 72/485 - (14%)

  Fly    35 KARKLELREDVRRMFQHAYDGYLRHASNYDELRPLTCDGHDT--WGSY-SLTLIDALDTLATMGN 96
            ||::.:::|    |.|.|:|.|..:|...:||||::..||.:  :||. ..|::||||||..|..
Zfish   158 KAKRAKIKE----MMQFAWDNYKHYAWGSNELRPVSKQGHSSNLFGSLKGATIVDALDTLYIMEM 218

  Fly    97 FTEFRRAARLLEEKMDFDRDINVSVFETNIRIVGGLLSAHLLSKRAGVELEPGWPCKGPLLRLAE 161
            :.||..|...:|:.:||:.:..:||||.|||.|||||||:.||   |.|:         ..:.|.
Zfish   219 YDEFEAATEWVEKNLDFNMNAEISVFEVNIRFVGGLLSAYYLS---GKEV---------FRKKAV 271

  Fly   162 DVARRLLPAFVTNTGMPYGTVNLRYGVPK------GETSITCTAGVGTFLIEFGTLSRLTGKTIY 220
            ::..:|||||.|.||:|:..:||:.||.:      |.:||  .|..||..:||..||.|:|:.::
Zfish   272 ELGEKLLPAFKTPTGVPWALLNLKSGVGRNWPWASGGSSI--LAEYGTLHLEFMHLSALSGRPVF 334

  Fly   221 EDVAMKAVHALWAYRSPIGLFGNHIDVQSGRWTALDSGIGAGVDSLFEYLVKASVLLNR--PELL 283
            .:..|.....|.....|.||:.|:::..||:|......:|...||.:|||:||.::.::  .|..
Zfish   335 AEKVMNIRKVLTRLDKPQGLYPNYLNPNSGQWGQHHVSVGGLGDSFYEYLLKAWLMSDKIDEEGK 399

  Fly   284 ELFHEARAAIDKYM--RKEDWYVWVGMNKGRVTLPVFQSLEAFWPGILSIIGDTEPALRT----- 341
            :|:::|..||:|.:  :......::...||.:.......|..|..|::::..|..|..:|
Zfish   400 KLYYDALQAIEKNLIRKSSGGLTYIAEWKGGLLEHKMGHLTCFAGGMIALGADGAPDEKTGHQME 464

  Fly   342 ----ISR-----YIGVWKKYGFLPEFYNIAAG-EA---SPNREVYPLRPELIESAMYLYRATGNE 393
                |:|     |:....|.|  ||.:....| ||   ..|.:.:.||||:||:.||::|.|.:.
Zfish   465 LAAEIARTCHESYVRTNLKLG--PEAFRFDGGVEAIATRQNEKYFILRPEVIETYMYMWRFTHDP 527

  Fly   394 YLLEFGEHMLETLEFSAKTKCGYATIRNVVTH--EKENRMESFFLAETSKYLYLLFDEENFLHND 456
            ...::|...::.||...:.:.||:.:|:|.::  ..::..:||:||||.|||||||.:::.|..|
Zfish   528 KYRQWGWEAVQALEKHCRVEGGYSGVRDVYSNNPNHDDVQQSFYLAETLKYLYLLFSDDDHLPFD 592

  Fly   457 GSGGELLSTEDDVCVVQAGAYIFNTEAHPM 486
                               .::|||||||:
Zfish   593 -------------------HWVFNTEAHPL 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Edem1	NP_001259152.1	Glyco_hydro_47	48..486	CDD:460241	152/470 (32%)
man1a1	XP_694435.2	Glyco_hydro_47	167..605	CDD:460241	153/472 (32%)