Protein Alignment Edem1 and edem2

DIOPT Version :10

• Sequence 1: NP_001259152.1
• Gene: Edem1 / 31154
• FlyBaseID: FBgn0023511
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_001005031.1
• Gene: edem2 / 448548
• XenbaseID: XB-GENE-941890
• Length: 555
• Species: Xenopus tropicalis
• Alignment Length: 569
• Identity: 306/569 - (53%)
• Similarity: 386/569 - (67%)
• Gaps: 34/569 - (5%)

  Fly    10 YPGTLICAVLLVLLSTGVSGQKQYSKARKLELREDVRRMFQHAYDGYLRHASNYDELRPLTCDGH 74
            ||  |...:|..||....:..:..::....:.|:.|:.||.|||:.||.||..|||||||||||.
 Frog     6 YP--LYLGILGALLPGYHARDRGLTEEEMAQYRDRVKSMFYHAYNNYLDHAFPYDELRPLTCDGQ 68

  Fly    75 DTWGSYSLTLIDALDTLATMGNFTEFRRAARLLEEKMDFDRDINVSVFETNIRIVGGLLSAHLLS 139
            |||||:|||||||||||..:||.|||:|...:|::.:|||.|:|.||||||||:|||||||||.|
 Frog    69 DTWGSFSLTLIDALDTLLIIGNVTEFQRVVNVLQDTLDFDIDVNASVFETNIRVVGGLLSAHLFS 133

  Fly   140 KRAGVELEPGWPCKGPLLRLAEDVARRLLPAFVTNTGMPYGTVNLRYGVPKGETSITCTAGVGTF 204
            ||||:||||||||.|||||:||:.||:|||||.|.||||||||||..||...||.:|||||||||
 Frog   134 KRAGLELEPGWPCTGPLLRMAEEAARKLLPAFDTATGMPYGTVNLLRGVNPTETPVTCTAGVGTF 198

  Fly   205 LIEFGTLSRLTGKTIYEDVAMKAVHALWAYRSPIGLFGNHIDVQSGRWTALDSGIGAGVDSLFEY 269
            ::||.|||||||...:|.||.:|:..||..||.|||.|||:||.:.:|.|.|:||||||||.|||
 Frog   199 IVEFATLSRLTGDPQFEMVARRALRGLWESRSDIGLVGNHVDVMTSKWVAQDAGIGAGVDSYFEY 263

  Fly   270 LVKASVLLNRPELLELFHEARAAIDKYMRKEDWYVWVGMNKGRVTLPVFQSLEAFWPGILSIIGD 334
            |||.::||...||:.:|.|...|:..:.:.:||||||.|.||.||:||||||||||||:.|::||
 Frog   264 LVKGAILLQDEELMSMFLEYNKALQNFTKYDDWYVWVQMYKGTVTMPVFQSLEAFWPGLQSLVGD 328

  Fly   335 TEPALRTISRYIGVWKKYGFLPEFYNIAAGEASPNREVYPLRPELIESAMYLYRATGNEYLLEFG 399
            ....:|:...|..||:::|.|||||:|..|.....||.|||||||||||||||:||.:..|||.|
 Frog   329 IRSGMRSFLNYYTVWRQFGGLPEFYSIPQGFTVEKREGYPLRPELIESAMYLYKATRDPILLELG 393

  Fly   400 EHMLETLEFSAKTKCGYATIRNVVTHEKENRMESFFLAETSKYLYLLFDEENFLHNDGSGGELLS 464
            ...:|::|..:|..||:|||::|..|:.:|||||||||||.||||||||.:||:|||||..:|:.
 Frog   394 RDAVESIERISKVDCGFATIKDVRDHKLDNRMESFFLAETIKYLYLLFDPDNFIHNDGSTSDLVV 458

  Fly   465 TEDDVCVVQAGAYIFNTEAHPMDMSALHCCHAHNEDIYTSLDLQRFSPRAILERSKKRQVAVQEQ 529
            |....||:.||.|:|||||||:|.:|||||                          ||..|  ||
 Frog   459 TPYGECVMGAGGYVFNTEAHPIDPAALHCC--------------------------KRDSA--EQ 495

  Fly   530 WVPQCHPENNEFFN-KEDESVQAQDSEKE-QEREQSGTSTTMAVDIEVF 576
            |  :......|||: |...:.:||....: |.|.:|..::.::...:.|
 Frog   496 W--EVEDLVREFFSIKSSSNPKAQQHRPDSQNRNKSKRTSKLSCPSQPF 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Edem1	NP_001259152.1	Glyco_hydro_47	48..486	CDD:460241	275/437 (63%)
edem2	NP_001005031.1	Glyco_hydro_47	42..480	CDD:460241	275/437 (63%)