Protein Alignment Edem1 and man1a2

DIOPT Version :10

• Sequence 1: NP_001259152.1
• Gene: Edem1 / 31154
• FlyBaseID: FBgn0023511
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_001243551.1
• Gene: man1a2 / 335538
• ZFINID: ZDB-GENE-070912-390
• Length: 645
• Species: Danio rerio
• Alignment Length: 487
• Identity: 156/487 - (32%)
• Similarity: 245/487 - (50%)
• Gaps: 71/487 - (14%)

  Fly    40 ELREDVRRMFQHAYDGYLRHASNYDELRPLTCDGHDT--WGSYSL--TLIDALDTLATMGNFTEF 100
            |.|:.:|.|.:||:|.|.::...::||:||...||.|  :|:..:  |::||||||..||...||
Zfish   183 EKRDKIREMMKHAWDSYRQYGWGHNELKPLAKKGHSTNIFGNSQMGATIVDALDTLYIMGLHDEF 247

  Fly   101 RRAARLLEEKMDFDRDINVSVFETNIRIVGGLLSAHLLSKRAGVELEPGWPCKGPLLRLAEDVAR 165
            :.....:|:.:||..:..|||||.|||.:||||:|:.||.:...:|:            |..:|.
Zfish   248 KDGQEWIEQNLDFSVNAEVSVFEVNIRFIGGLLAAYYLSGQEVFKLK------------AVQLAE 300

  Fly   166 RLLPAFVTNTGMPYGTVNLRYGVPK------GETSITCTAGVGTFLIEFGTLSRLTGKTIYEDVA 224
            :|||||.|.||:|:..|||:.||.:      |.:||  .|..||..:||..|:.|||...|....
Zfish   301 KLLPAFNTPTGIPWAMVNLKSGVGRNWGWASGGSSI--LAEFGTLHMEFVHLTYLTGNPAYYQKV 363

  Fly   225 MKAVHALWAYRSPIGLFGNHIDVQSGRWTALDSGIGAGVDSLFEYLVKASVLLNR--PELLELFH 287
            |.....|.....|.||:.|:::.::|||....:.:|...||.:|||:||.::.::  .|..:.:.
Zfish   364 MHIRKLLAKMDRPNGLYPNYLNPRTGRWGQHHTSVGGLGDSFYEYLLKAWLMSDKTDAEARKTYD 428

  Fly   288 EARAAIDKYM-RKED-WYVWVGMNKGRVTLPVFQSLEAFWPGILSIIGDTEP------------- 337
            :|..||:::: ||.: ...::|..|..........|..|..|:.::..|..|
Zfish   429 DAIEAIERHLIRKSNGGLTFIGEWKNGHLERKMGHLTCFAGGMFALGADGSPDDKAGHYLQLGAE 493

  Fly   338 -ALRTISRYIGVWKKYGFLPEFYNIAAG-EA---SPNREVYPLRPELIESAMYLYRATGNEYLLE 397
             |......|.....|.|  ||.:...:| ||   ..|.:.|.||||:||:..|::|.|.:....:
Zfish   494 IAHTCHESYDRTVLKLG--PEAFKFDSGLEAVAVRQNEKYYILRPEVIETYWYMWRFTHDPKYRQ 556

  Fly   398 FGEHMLETLEFSAKTKCGYATIRNVVTHEK--ENRMESFFLAETSKYLYLLFDEENFLHNDGSGG 460
            :|....:.::...:...|::.:::|.:...  ::..:|||||||.|||||||          |..
Zfish   557 WGWEAAQAIDKHCRVSGGFSGVKDVYSSNPTYDDVQQSFFLAETLKYLYLLF----------SSD 611

  Fly   461 ELLSTEDDVCVVQAGAYIFNTEAHPMDMSALH 492
            |||..|:         ::|||||||:.:  ||
Zfish   612 ELLPLEN---------WVFNTEAHPLPV--LH 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Edem1	NP_001259152.1	Glyco_hydro_47	48..486	CDD:460241	150/471 (32%)
man1a2	NP_001243551.1	Glyco_hydro_47	191..630	CDD:460241	151/473 (32%)