Protein Alignment Edem1 and F10C2.5

DIOPT Version :9

• Sequence 1: NP_001259152.1
• Gene: Edem1 / 31154
• FlyBaseID: FBgn0023511
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_506018.1
• Gene: F10C2.5 / 179653
• WormBaseID: WBGene00008646
• Length: 781
• Species: Caenorhabditis elegans
• Alignment Length: 728
• Identity: 328/728 - (45%)
• Similarity: 430/728 - (59%)
• Gaps: 135/728 - (18%)

  Fly    42 REDVRRMFQHAYDGYLRHASNYDELRPLTCDGHDTWGSYSLTLIDALDTLATMGNFTEFRRAARL 106
            ||.|::||.|||:|||.||...|||:|:||.|.|||||:||:||||||||..|||.||||||..|
 Worm    43 REKVQKMFYHAYNGYLDHAFPLDELKPITCVGQDTWGSFSLSLIDALDTLLVMGNTTEFRRAVSL 107

  Fly   107 LEEKMDFDRDINVSVFETNIRIVGGLLSAHLLS---KRAGVELEPGWPCKGPLLRLAEDVARRLL 168
            :.||...|.::||||||||||:||||:|||:|:   |...|:.| |:||..|||:||..:|.||:
 Worm   108 VLEKARDDANVNVSVFETNIRVVGGLISAHMLAGRHKDLVVDWE-GYPCDSPLLKLAVKMADRLM 171

  Fly   169 PAFVTNTGMPYGTVNLRYGVPKGETSITCTAGVGTFLIEFGTLSRLTGKTIYEDVAMKAVHALWA 233
            |||.|.||||||||||:|||.|.||.||||||||||||||||||||||...||.||:||:.|||:
 Worm   172 PAFNTETGMPYGTVNLKYGVHKDETPITCTAGVGTFLIEFGTLSRLTGDDKYEKVALKALDALWS 236

  Fly   234 YRSPIGLFGNHIDVQSGRWTALDSGIGAGVDSLFEYLVKASVLLNRPELLELFHEARAAIDKYMR 298
            .||||||.||||:||:|:|||.||||||||||.||||.|.:.|..||.|::.|||...:|:|::|
 Worm   237 TRSPIGLVGNHINVQTGQWTATDSGIGAGVDSYFEYLAKGAYLFRRPSLMKQFHEHATSINKHVR 301

  Fly   299 KEDWYVWVGMNKGRVTLPVFQSLEAFWPGILSIIGDTEPALRTISRYIGVWKKYGFLPEFYNIAA 363
            |.:|::||.|.||.|:||:||||||||||.|:::||.:.|.|.:..|..|.:||||.||||||..
 Worm   302 KGEWFMWVSMAKGSVSLPIFQSLEAFWPGTLTMVGDVQDASRIMLTYSEVIRKYGFPPEFYNIHN 366

  Fly   364 GEASPNREVYPLRPELIESAMYLYRATGNEYLLEFGEHMLETLEFSAKTKCGYATIRNVVTHEKE 428
            .|....|..:|||||::||.|||||||.:|..||.|..|::.:|.||:||||||||.||..|..|
 Worm   367 EEPGEKRAAFPLRPEMVESLMYLYRATKDETWLELGAEMIDAIESSARTKCGYATINNVKEHSIE 431

  Fly   429 NRMESFFLAETSKYLYLLFDEENFLHNDGSGGELLSTEDDV-CVVQAGAYIFNTEAHPMDMSALH 492
            :||||||||||:||||||||..||:|:.|....:|::..:: ||:..|.|||||||||:|...|.
 Worm   432 DRMESFFLAETTKYLYLLFDPTNFIHSKGDQARILTSPKNLTCVIYGGGYIFNTEAHPVDPGMLD 496

  Fly   493 CCHAHNEDIYTSLDLQRFSPRAILERSKKRQVAVQEQWVPQCHPENNEFFNKEDESVQAQDSEKE 557
            ||.                    ::..:.::|.|::             .|..||..:...:||.
 Worm   497 CCS--------------------VQAKRDQEVGVKQ-------------VNNGDEHEKMNRTEKG 528

  Fly   558 QER---EQSGTSTTMAVDIEVFDEFQQPAGDLLVSNFEQIREERE-LNESLHRNVVARNQLTV-- 616
            .|:   .|.|.:..: ::.||.::.::.      |...:|..|.| :.|:.|:.::...::.|
 Worm   529 GEKYFENQYGKNENL-IEFEVDEKLKKE------SEKRKIELEAEKVKENSHKAMLKVREILVRA 586

  Fly   617 SDLDEFFAQRRESFASASEALNYVKTFMGNYTMDVAFIRGLQLYDTNMSSVLGTGAQKEYESRMR 681
            ...||...:..|:..||.:.::                   |||             |.|
 Worm   587 HQKDEAMQRNGETSDSARKLMD-------------------QLY-------------KAY----- 614

  Fly   682 TLWQLYELQQQYVANIRVIQGLGLLTFPADGDRIPSHLTEVLDSLDKSAHLEHMDLQDLETRVSN 746
                                              |:|..| |::|:|.|.:|..:||.||
 Worm   615 ----------------------------------PNHTAE-LENLNKEAIIEFEELQHLE----- 639

  Fly   747 TSSPQLAHIREVI 759
                   .|||::
 Worm   640 -------DIRELV 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Edem1	NP_001259152.1	Glyco_hydro_47	48..486	CDD:279825	276/441 (63%)
F10C2.5	NP_506018.1	Glyco_hydro_47	49..489	CDD:279825	275/440 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156192
Domainoid	1	1.000	552	1.000	Domainoid score	I120
eggNOG	1	0.900	-	-		E1_KOG2429
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H10075
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D434316at2759
OrthoFinder	1	1.000	-	-		FOG0000713
OrthoInspector	1	1.000	-	-		oto20675
orthoMCL	1	0.900	-	-		OOG6_101442
Panther	1	1.100	-	-	LDO	PTHR45679
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3607
SonicParanoid	1	1.000	-	-		X4562
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.780