Protein Alignment Edem1 and MMP24-AS1-EDEM2

DIOPT Version :10

• Sequence 1: NP_001259152.1
• Gene: Edem1 / 31154
• FlyBaseID: FBgn0023511
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_001341937.1
• Gene: MMP24-AS1-EDEM2 / 111089941
• -ID: -
• Length: 537
• Species: Homo sapiens
• Alignment Length: 518
• Identity: 300/518 - (57%)
• Similarity: 379/518 - (73%)
• Gaps: 12/518 - (2%)

  Fly    48 MFQHAYDGYLRHASNYDELRPLTCDGHDTWGSYSLTLIDALDTLATMGNFTEFRRAARLLEEKMD 112
            ||.||||.||.:|..:||||||||||||||||:|||||||||||..:||.:||:|...:|::.:|
Human     1 MFYHAYDSYLENAFPFDELRPLTCDGHDTWGSFSLTLIDALDTLLILGNVSEFQRVVEVLQDSVD 65

  Fly   113 FDRDINVSVFETNIRIVGGLLSAHLLSKRAGVELEPGWPCKGPLLRLAEDVARRLLPAFVTNTGM 177
            ||.|:|.||||||||:||||||||||||:||||:|.||||.|||||:||:.||:|||||.|.|||
Human    66 FDIDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGPLLRMAEEAARKLLPAFQTPTGM 130

  Fly   178 PYGTVNLRYGVPKGETSITCTAGVGTFLIEFGTLSRLTGKTIYEDVAMKAVHALWAYRSPIGLFG 242
            |||||||.:||..|||.:|||||:|||::||.|||.|||..::||||..|:..||..||.|||.|
Human   131 PYGTVNLLHGVNPGETPVTCTAGIGTFIVEFATLSSLTGDPVFEDVARVALMRLWESRSDIGLVG 195

  Fly   243 NHIDVQSGRWTALDSGIGAGVDSLFEYLVKASVLLNRPELLELFHEARAAIDKYMRKEDWYVWVG 307
            |||||.:|:|.|.|:||||||||.||||||.::||...:|:.:|.|...||..|.|.:|||:||.
Human   196 NHIDVLTGKWVAQDAGIGAGVDSYFEYLVKGAILLQDKKLMAMFLEYNKAIRNYTRFDDWYLWVQ 260

  Fly   308 MNKGRVTLPVFQSLEAFWPGILSIIGDTEPALRTISRYIGVWKKYGFLPEFYNIAAGEASPNREV 372
            |.||.|::||||||||:|||:.|:|||.:.|:||...|..|||::|.|||||||..|.....||.
Human   261 MYKGTVSMPVFQSLEAYWPGLQSLIGDIDNAMRTFLNYYTVWKQFGGLPEFYNIPQGYTVEKREG 325

  Fly   373 YPLRPELIESAMYLYRATGNEYLLEFGEHMLETLEFSAKTKCGYATIRNVVTHEKENRMESFFLA 437
            |||||||||||||||||||:..|||.|...:|::|..:|.:||:|||:::..|:.:|||||||||
Human   326 YPLRPELIESAMYLYRATGDPTLLELGRDAVESIEKISKVECGFATIKDLRDHKLDNRMESFFLA 390

  Fly   438 ETSKYLYLLFDEENFLHNDGSGGELLSTEDDVCVVQAGAYIFNTEAHPMDMSALHCCHAHNEDIY 502
            ||.||||||||..||:||:||..:.:.|....|::.||.|||||||||:|.:|||||....|:.:
Human   391 ETVKYLYLLFDPTNFIHNNGSTFDAVITPYGECILGAGGYIFNTEAHPIDPAALHCCQRLKEEQW 455

  Fly   503 TSLDLQR--FSPRAILERSK---KRQVAVQEQWVPQCHPENNEFFNKEDESVQAQDSEKEQER 560
            ...||.|  :|    |:||:   ::.......|.|...|  ...|:.|:.. ||::.:..:::
Human   456 EVEDLMREFYS----LKRSRSKFQKNTVSSGPWEPPARP--GTLFSPENHD-QARERKPAKQK 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Edem1	NP_001259152.1	Glyco_hydro_47	48..486	CDD:460241	278/437 (64%)
MMP24-AS1-EDEM2	NP_001341937.1	Glyco_hydro_47	1..439	CDD:460241	278/437 (64%)