Protein Alignment mip130 and Lin9

DIOPT Version :9

• Sequence 1: NP_569958.2
• Gene: mip130 / 31153
• FlyBaseID: FBgn0023509
• Length: 986
• Species: Drosophila melanogaster
• Sequence 2: NP_001096652.2
• Gene: Lin9 / 72568
• MGIID: 1919818
• Length: 558
• Species: Mus musculus
• Alignment Length: 710
• Identity: 216/710 - (30%)
• Similarity: 308/710 - (43%)
• Gaps: 207/710 - (29%)

  Fly    83 DEEPDSNENSAPEEQVEPPAFSLATLGLQRVGSAPPPKPKVQKAPI-------PTLNARGMPARI 140
            |:.||  |:|:.:..|.....||:....::..|       :||.|:       |.:.   ||.|.
Mouse    21 DQLPD--ESSSAKALVSLKEGSLSNTWNEKYSS-------LQKTPVWKGRNAGPAVE---MPFRN 73

  Fly   141 RKRNRLFYDENIINDDKPLRMSLAPKKTPGRPPQSAGGGSSQKIPLTPSKVLKKRKGVVSRYMRS 205
            .||:|||.||    ||:.:.     .|:|.|         :|::.:.|.|.
Mouse    74 SKRSRLFSDE----DDRQIN-----TKSPKR---------NQRVAMIPQKF-------------- 106

  Fly   206 SEQGTNSVSASNQPQLLGKHKKATPSKSQSVGSKLGSGGPKTGRGAHFIGKGTAAAVAAVAAAEE 270
                |.::|              ||.|..|
Mouse   107 ----TATMS--------------TPDKKAS----------------------------------- 118

  Fly   271 EANQAEAAALANKRLGQSIGLRLRNLLKLPKAHKWAIAEWFYSYVDKPLFECRDEFMNHVNELAP 335
                            |.||.||||||||||||||.|.|||||.:||||||..::|...:.|..|
Mouse   119 ----------------QKIGFRLRNLLKLPKAHKWCIYEWFYSNIDKPLFEGDNDFCVCLKESFP 167

  Fly   336 RLGTRSLIRHEWVNIRRRMGRPRRCSAKFFSEERKELDRKRQVIRTLQSRKPGEFKDSVSMLSDM 400
            .|.||.|.|.||..|||.||:|||||:.||.|||..|.:|||.||.||.||..:    ||...|:
Mouse   168 NLKTRKLTRVEWGKIRRLMGKPRRCSSAFFEEERSALKQKRQKIRLLQQRKVAD----VSQFKDL 228

  Fly   401 PEKIPMTLPLGTKVTARLRSPQDGIFAGTVAAYDSLNAMYRVTFERIGLGTHAIPDYEIVSENFH 465
            |::||:.|.:|||||||||...||:|.|.:.|.|:|||.|||||:|.|||||.|||||::|...|
Mouse   229 PDEIPLPLVIGTKVTARLRGIHDGLFTGQIDAVDTLNATYRVTFDRTGLGTHTIPDYEVLSNEPH 293

  Fly   466 EMLPLHSFTKDFRPNLMSIYQTNNLGFTTNLGFTANLTNNYLQKKEKIDGGAGAAAGAGSLYF-- 528
            |.:|:.:|.:..||                                             |.:|
Mouse   294 ETMPISAFGQKQRP---------------------------------------------SRFFMT 313

  Fly   529 KPQKHLATNNAAARNALSMKLNKSDPLLGQDSVGVSPIRQQLTRN-----RGYSTSLLEHLVRLE 588
            .|:.|...       .|...:...||||||     ||.|.:::.:     .|:....|..:.:|.
Mouse   314 PPRLHYTP-------PLQSPITDGDPLLGQ-----SPWRSKVSGSDTETLGGFPVEFLIQVTKLS 366

  Fly   589 KYIAVKADRIQRLNKMNGTAELAMGDMISHDENGDRHRRQIAVNFQRQYAFNIVTIERINAELMF 653
            |.:.:|.:.|::|.:||..||....           :...|.:.|||:||..::.:|::|.:|..
Mouse   367 KILMIKKEHIKKLREMNTEAEKLKS-----------YSMPIGIEFQRRYATIVLELEQLNKDLNK 420

  Fly   654 ELTKVQELSSSLTRNPNVQAMISPTYLREECRAKASQTVDDINKG----MVKNTRMIKLLKDLTT 714
            .|.|||:....|..:..:|....||.:|..|..:|.:.|...|..    .|:|..:..|:..||.
Mouse   421 VLHKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEIVRQANSASGQPCVENENLTDLISRLTA 485

  Fly   715 LLIVTQNL--GGDCEVSEVNEVLEGCLEEVRSNLICSENREVFQMSVQGRLEYIAMDISR 772
            :|:..:.|  |||....|...:.:. |.::: |.|.:.|...||.:|:..:.:|...:|:
Mouse   486 ILLQIKCLAEGGDLNSFEFKSLTDS-LNDIK-NTIDASNISCFQNNVEIHVAHIQSGLSQ 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mip130	NP_569958.2	DIRP	311..419	CDD:284095	58/107 (54%)
Lin9	NP_001096652.2	DIRP	143..247	CDD:284095	58/107 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831124
Domainoid	1	1.000	151	1.000	Domainoid score	I4346
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H35252
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005813
OrthoInspector	1	1.000	-	-		oto95088
orthoMCL	1	0.900	-	-		OOG6_106727
Panther	1	1.100	-	-	LDO	PTHR21689
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2615
SonicParanoid	1	1.000	-	-		X4787
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.870