Protein Alignment mip130 and Lin9

DIOPT Version :9

• Sequence 1: NP_569958.2
• Gene: mip130 / 31153
• FlyBaseID: FBgn0023509
• Length: 986
• Species: Drosophila melanogaster
• Sequence 2: XP_001067807.3
• Gene: Lin9 / 689523
• RGDID: 1591104
• Length: 558
• Species: Rattus norvegicus
• Alignment Length: 708
• Identity: 216/708 - (30%)
• Similarity: 308/708 - (43%)
• Gaps: 203/708 - (28%)

  Fly    83 DEEPDSNENSAPEEQVEPPAFSLATLGLQRVGSAPPPKPKVQKAPI-------PTLNARGMPARI 140
            |:.||  |:|:.:..|.....||:....::..|       :||.|:       |.:.   ||.|.
  Rat    21 DQLPD--ESSSAKALVSLKEGSLSNTWNEKYSS-------LQKTPVWKGRNAGPAVE---MPFRN 73

  Fly   141 RKRNRLFYDENIINDDKPLRMSLAPKKTPGRPPQSAGGGSSQKIPLTPSKVLKKRKGVVSRYMRS 205
            .||:|||.||    ||:.:.     .|:|.|         :|::.:.|.|.
  Rat    74 SKRSRLFSDE----DDRQIN-----TKSPKR---------NQRVAMIPQKF-------------- 106

  Fly   206 SEQGTNSVSASNQPQLLGKHKKATPSKSQSVGSKLGSGGPKTGRGAHFIGKGTAAAVAAVAAAEE 270
                |.::|              ||.|..|
  Rat   107 ----TATMS--------------TPDKKAS----------------------------------- 118

  Fly   271 EANQAEAAALANKRLGQSIGLRLRNLLKLPKAHKWAIAEWFYSYVDKPLFECRDEFMNHVNELAP 335
                            |.||.||||||||||||||.|.|||||.:||||||..::|...:.|..|
  Rat   119 ----------------QKIGFRLRNLLKLPKAHKWCIYEWFYSNIDKPLFEGDNDFCVCLKESFP 167

  Fly   336 RLGTRSLIRHEWVNIRRRMGRPRRCSAKFFSEERKELDRKRQVIRTLQSRKPGEFKDSVSMLSDM 400
            .|.||.|.|.||..|||.||:|||||:.||.|||..|.:|||.||.||.||..:    ||...|:
  Rat   168 NLKTRKLTRVEWGKIRRLMGKPRRCSSAFFEEERSALKQKRQKIRLLQQRKVAD----VSQFKDL 228

  Fly   401 PEKIPMTLPLGTKVTARLRSPQDGIFAGTVAAYDSLNAMYRVTFERIGLGTHAIPDYEIVSENFH 465
            |::||:.|.:|||||||||...||:|.|.:.|.|:|||.|||||:|.|||||.|||||::|...|
  Rat   229 PDEIPLPLVIGTKVTARLRGIHDGLFTGQIDAVDTLNATYRVTFDRTGLGTHTIPDYEVLSNEPH 293

  Fly   466 EMLPLHSFTKDFRPNLMSIYQTNNLGFTTNLGFTANLTNNYLQKKEKIDGGAGAAAGAGSLYFKP 530
            |.:|:.:|.:..||:..         |.|                                  .|
  Rat   294 ETMPIAAFGQKQRPSRF---------FMT----------------------------------PP 315

  Fly   531 QKHLATNNAAARNALSMKLNKSDPLLGQDSVGVSPIRQQLTRN-----RGYSTSLLEHLVRLEKY 590
            :.|...       .|...:...||||||     ||.|.:::.:     .|:....|..:.:|.|.
  Rat   316 RLHYTP-------PLQSPITDGDPLLGQ-----SPWRSKISGSDTETLGGFPVEFLIQVTKLSKI 368

  Fly   591 IAVKADRIQRLNKMNGTAELAMGDMISHDENGDRHRRQIAVNFQRQYAFNIVTIERINAELMFEL 655
            :.:|.:.|::|.:||..||....           :...|.:.|||:||..::.:|::|.:|...|
  Rat   369 LMIKKEHIKKLREMNTEAEKLKS-----------YSMPIGIEFQRRYATIVLELEQLNKDLNKVL 422

  Fly   656 TKVQELSSSLTRNPNVQAMISPTYLREECRAKASQTVDDINKG----MVKNTRMIKLLKDLTTLL 716
            .|||:....|..:..:|....||.:|..|..:|.:.|...|..    .|:|..:..|:..||.:|
  Rat   423 HKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEIVRQANSASGQPCVENENLTDLISRLTAIL 487

  Fly   717 IVTQNL--GGDCEVSEVNEVLEGCLEEVRSNLICSENREVFQMSVQGRLEYIAMDISR 772
            :..:.|  |||....|...:.:. |.::: |.|.:.|...||.:|:..:.:|...:|:
  Rat   488 LQIKCLAEGGDLNSFEFKSLTDS-LNDIK-NTIDASNISCFQNNVEIHVAHIQSGLSQ 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mip130	NP_569958.2	DIRP	311..419	CDD:284095	58/107 (54%)
Lin9	XP_001067807.3	DIRP	143..247	CDD:399528	58/107 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334844
Domainoid	1	1.000	151	1.000	Domainoid score	I4260
eggNOG	1	0.900	-	-		E1_KOG1019
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H35252
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D279992at33208
OrthoFinder	1	1.000	-	-		FOG0005813
OrthoInspector	1	1.000	-	-		oto98582
orthoMCL	1	0.900	-	-		OOG6_106727
Panther	1	1.100	-	-	LDO	PTHR21689
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4787
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.750