Protein Alignment mip130 and aly

DIOPT Version :10

• Sequence 1: NP_569958.2
• Gene: mip130 / 31153
• FlyBaseID: FBgn0023509
• Length: 986
• Species: Drosophila melanogaster
• Sequence 2: NP_524857.3
• Gene: aly / 45960
• FlyBaseID: FBgn0004372
• Length: 568
• Species: Drosophila melanogaster
• Alignment Length: 609
• Identity: 132/609 - (21%)
• Similarity: 237/609 - (38%)
• Gaps: 173/609 - (28%)

  Fly   213 VSASNQPQLLGKHKKATPSKSQSVGSKLGSGGPKTGRGAHFIGKGTAAAVAAVAAAEEEANQAEA 277
            :..|.:|::.|:.|....||                |..:|..|.:..:|......:.:..:.|.
  Fly    66 IRISEKPEIQGRIKPGVASK----------------RTENFTKKPSNISVDVSEDEKAKEKEKEQ 114

  Fly   278 AALANKRLGQSIGLRLRNLLKLPKAHKWAIAEWFYSYVDKPLFECRDEFMNHVNELAPRLGTRSL 342
            ...:|..:   :|.||.|.||...:|:|...|:..|::|||......:....:.|..|.|.:..:
  Fly   115 DPYSNDFI---LGKRLYNFLKYLSSHRWIWCEFVDSFLDKPTLTMGYDMKRFIAEYCPLLHSCFM 176

  Fly   343 IRHEWVNIRRRMGRPRRCSAKFFSEERKELDRKRQVIRTLQSRK--PGEFKDSVSMLSDMPEKIP 405
            .|..|..:||.||:.||.||.|...||:||:.:|:::|.||..|  |   |::|..|..:|:::|
  Fly   177 PRRGWQLVRRNMGKARRFSAAFIELEREELECQRRIVRQLQQHKFNP---KENVGYLDQIPKRVP 238

  Fly   406 MTLPLGTKVTARLRSPQ-DGIFAGTVAAYDSLNAMYRVTFER----IGLGTHAIPDYEIVSENFH 465
            :.|.....|::.|.... :||..|||..||..:..|.|.|.|    :.|   ::||.::.|:...
  Fly   239 LPLAKDATVSSFLHGNSFEGIVNGTVMGYDPQDYTYLVRFNRNDNAVVL---SLPDSQLYSDEET 300

  Fly   466 EMLPLHSFTKDFRPNLMSIYQTNNLGFTTNLGFTANLTNNYLQKKEKIDGGAGAAAGAGSLYFKP 530
            ..:||
  Fly   301 AAVPL------------------------------------------------------------ 305

  Fly   531 QKHLATNNAAARNALSMKLNKSDPLLGQDSVGVSPIRQQLTRNRGYSTSLLEHLVRLEKYIAVKA 595
                         ::.|:.|||..::.:.:      :.:...|:.|:..|||.::|:.|...||.
  Fly   306 -------------SIIMRGNKSSSVISESA------KTEKFGNKRYTKELLESVLRVGKLQDVKH 351

  Fly   596 DRIQRLNKMNGTAELAMGDMISHDENGDRHRRQIA------VNFQRQYAFNIVTIERINAEL--- 651
            ..:..|.:||       .|..:..|.|....|:.|      .|.||:|:.:::|:.|:||::
  Fly   352 KILMDLARMN-------EDFETFKEIGSSSSRRDAKVTPQRENLQRRYSASMITLHRVNADILEP 409

  Fly   652 -------MFELTKVQELSSSLTRNPNVQAMISPTYLREECRAKASQ---TVDDINKGMVKNTRMI 706
                   :.|..|..|...|....|     .|..|  ::||.:|.|   |..|.....:::.|..
  Fly   410 LRILHDYLVEYQKQDEEEESKRGRP-----ASEVY--QKCRMQAEQDLKTAADEKFLKIESDRTQ 467

  Fly   707 KLLKDLTTLLIVTQNLGGDCEVSEVNEVLEGCLEEVRSNLICSENREVFQMSVQGRLEYIAMDIS 771
            :.:::|.|:|.:...||     .|.:..||..:.::.::::                :.|...:.
  Fly   468 EFVRNLHTILYLNGKLG-----RENSSNLETIIADLVTHMV----------------DNIQPSLG 511

  Fly   772 RRLEEKSLSRVADGDDDIKSLKSE 795
            |:|:        ||.|.::.|:.:
  Fly   512 RKLK--------DGVDSLEPLRQQ 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mip130	NP_569958.2	DIRP	310..419	CDD:461955	35/110 (32%)
		LIN9_C	455..771	CDD:437270	57/334 (17%)
		PHA03169	<783..>911	CDD:223003	4/13 (31%)
aly	NP_524857.3	DIRP	144..252	CDD:461955	35/110 (32%)