Protein Alignment mip130 and LIN9

DIOPT Version :9

• Sequence 1: NP_569958.2
• Gene: mip130 / 31153
• FlyBaseID: FBgn0023509
• Length: 986
• Species: Drosophila melanogaster
• Sequence 2: XP_024302333.1
• Gene: LIN9 / 286826
• HGNCID: 30830
• Length: 581
• Species: Homo sapiens
• Alignment Length: 660
• Identity: 199/660 - (30%)
• Similarity: 283/660 - (42%)
• Gaps: 212/660 - (32%)

  Fly   123 VQKAPI----PTLNARGMPARIRKRNRLFYDENIINDDKPLRMSLAPKKTPGRPPQSAGGGSSQK 183
            :||.|:    .|.:|..||.|..||:|||.||    ||:.:. :.:||:             :|:
Human   109 LQKTPVWKGRNTSSAVEMPFRNSKRSRLFSDE----DDRQIN-TRSPKR-------------NQR 155

  Fly   184 IPLTPSKVLKKRKGVVSRYMRSSEQGTNSVSASNQPQLLGKHKKATPSKSQSVGSKLGSGGPKTG 248
            :.:.|.|.                  |.::|              ||.|..|
Human   156 VAMVPQKF------------------TATMS--------------TPDKKAS------------- 175

  Fly   249 RGAHFIGKGTAAAVAAVAAAEEEANQAEAAALANKRLGQSIGLRLRNLLKLPKAHKWAIAEWFYS 313
                                                  |.||.||||||||||||||.|.|||||
Human   176 --------------------------------------QKIGFRLRNLLKLPKAHKWCIYEWFYS 202

  Fly   314 YVDKPLFECRDEFMNHVNELAPRLGTRSLIRHEWVNIRRRMGRPRRCSAKFFSEERKELDRKRQV 378
            .:||||||..::|...:.|..|.|.||.|.|.||..|||.||:|||||:.||.|||..|.:|||.
Human   203 NIDKPLFEGDNDFCVCLKESFPNLKTRKLTRVEWGKIRRLMGKPRRCSSAFFEEERSALKQKRQK 267

  Fly   379 IRTLQSRKPGEFKDSVSMLSDMPEKIPMTLPLGTKVTARLRSPQDGIFAGTVAAYDSLNAMYRVT 443
            ||.||.||..:    ||...|:|::||:.|.:|||||||||...||:|.|.:.|.|:|||.||||
Human   268 IRLLQQRKVAD----VSQFKDLPDEIPLPLVIGTKVTARLRGVHDGLFTGQIDAVDTLNATYRVT 328

  Fly   444 FERIGLGTHAIPDYEIVSENFHEMLPLHSFTKDFRPNLMSIYQTNNLGFTTNLGFTANLTNNYLQ 508
            |:|.|||||.|||||::|...||.:|:.:|.:..||:
Human   329 FDRTGLGTHTIPDYEVLSNEPHETMPIAAFGQKQRPS---------------------------- 365

  Fly   509 KKEKIDGGAGAAAGAGSLYFKPQKHLATNNAAARNALSMKLNKSDPLLGQDSVGVSPIRQQLTRN 573
                            ..:..|.                :|:.:.||       .|||
Human   366 ----------------RFFMTPP----------------RLHYTPPL-------QSPI------- 384

  Fly   574 RGYSTSLLEHLVRLEKYIAVKADRIQRLNKMNGTAELAMGDMISHDENGDRHRRQIAVNFQRQYA 638
                      :.||.|.:.:|.:.|::|.:||..||....           :...|::.|||:||
Human   385 ----------ITRLSKILMIKKEHIKKLREMNTEAEKLKS-----------YSMPISIEFQRRYA 428

  Fly   639 FNIVTIERINAELMFELTKVQELSSSLTRNPNVQAMISPTYLREECRAKASQTVDDINKG----M 699
            ..::.:|::|.:|...|.|||:....|..:..:|....||.:|..|..:|.:.|...|..    .
Human   429 TIVLELEQLNKDLNKVLHKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEIVRHANSSTGQPC 493

  Fly   700 VKNTRMIKLLKDLTTLLIVTQNL--GGDCEVSEVNEVLEGCLEEVRSNLICSENREVFQMSVQGR 762
            |:|..:..|:..||.:|:..:.|  |||....|...:.:. |.:::|.:..| |...||.:|:..
Human   494 VENENLTDLISRLTAILLQIKCLAEGGDLNSFEFKSLTDS-LNDIKSTIDAS-NISCFQNNVEIH 556

  Fly   763 LEYIAMDISR 772
            :.:|...:|:
Human   557 VAHIQSGLSQ 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mip130	NP_569958.2	DIRP	311..419	CDD:284095	58/107 (54%)
LIN9	XP_024302333.1	DIRP	200..304	CDD:310884	58/107 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141178
Domainoid	1	1.000	151	1.000	Domainoid score	I4356
eggNOG	1	0.900	-	-		E1_KOG1019
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H35252
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D279992at33208
OrthoFinder	1	1.000	-	-		FOG0005813
OrthoInspector	1	1.000	-	-		oto91505
orthoMCL	1	0.900	-	-		OOG6_106727
Panther	1	1.100	-	-	LDO	PTHR21689
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2615
SonicParanoid	1	1.000	-	-		X4787
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.740