Protein Alignment mip130 and lin-9

DIOPT Version :9

• Sequence 1: NP_569958.2
• Gene: mip130 / 31153
• FlyBaseID: FBgn0023509
• Length: 986
• Species: Drosophila melanogaster
• Sequence 2: NP_001023016.1
• Gene: lin-9 / 176256
• WormBaseID: WBGene00002998
• Length: 644
• Species: Caenorhabditis elegans
• Alignment Length: 685
• Identity: 158/685 - (23%)
• Similarity: 299/685 - (43%)
• Gaps: 128/685 - (18%)

  Fly   121 PKVQKAPIPTLNARGMPARIRKRNRLFYDENIINDDKPLRMSLAPKKTPGRPPQSAGGGSSQKI- 184
            |....:|........:|:|.|.      :|..::..:.::.:.:|||:|.:  :..||..|..:
 Worm    19 PDRTSSPYSLRETSKVPSRYRN------EELYLSPSRSIKRTGSPKKSPAK--RLNGGRDSPSVN 75

  Fly   185 PLTPSKVLKKRKGVVSRYMRSSEQGTNSVSASNQPQLLGKHKKATPSKSQSVGSKLGSGGPKTGR 249
            .||.:..|.    ::::.....|..:.::....||    |.::..|.::.::       .|....
 Worm    76 SLTRNSSLT----MLAKAALDYESSSCALEYIFQP----KEERRPPRRALAL-------SPPPAP 125

  Fly   250 GAHFIGKGTAA------AVAAVAAAEEEANQA--------------------EAAALANK----- 283
            ....:.|....      .||.:...:..||..                    |.:|:..:
 Worm   126 SNDLLAKDLEMIEMHQNLVAGLDDLDNPANMTNEAVEHRDTQSFFNMFSTDQERSAMMKQFKTYK 190

  Fly   284 -RLGQSIGL-------RLRNLLKLPKAHKWAIAEWFYSYVDKPLFECRDEFMNHVNELAPRLGTR 340
             :..:.:..       :|.|||:..||.:|.:.|:|||.:|:.:|:..:||...:.|..|.|...
 Worm   191 NQTSEDVSTFMRANIKKLYNLLRYKKARQWVMCEFFYSAIDEQIFKEENEFATIIRESFPNLKNW 255

  Fly   341 SLIRHEWVNIRRRMGRPRRCSAKFFSEERKELDRKRQVIRTLQSRKPGEFKDSVSM-LSDMPEKI 404
            :|.|.||.:||:.:|:|||||..||.|||..|:.||..||::..   |.:.:..|: |.|:|.|:
 Worm   256 NLTRIEWRSIRKLLGKPRRCSKVFFEEERMYLEEKRMKIRSVYE---GSYLNDPSIDLKDLPAKL 317

  Fly   405 PMTLPLGTKVTARLRSPQDGIFAGTVAAYDSLNAMYRVTFERIGLGTHAIPDYEIVSENFHEMLP 469
            |..:.:|.:|.||:|:|.|||::|.:.|.  :...:|:.|::..:....:.|.||:.:...::|.
 Worm   318 PRPMVVGNRVFARIRNPYDGIYSGIIDAV--IPKGFRIIFDKPDIPPTLVSDTEILLDGKLDLLS 380

  Fly   470 LHSFTKDFRPNLMSIYQTNNLGFTTNLGFTANLTNNYLQKKEKIDGGAGAAAGAGSLYFKPQKHL 534
            :..|          |.|.|:                      |:..|......|  :......||
 Worm   381 IAYF----------IEQANS----------------------KLPSGVRPFVAA--VRDSSHPHL 411

  Fly   535 ATNNAAARNAL-SMKLNKS-DPLLGQDSVGVSPIRQQLTRNRGYSTSLLEHLVRLEKYIAVKADR 597
                  .|:.| |.|:.:| .||:|.:...::....::..|  :....|.:||:|.|.|.:|...
 Worm   412 ------VRDVLVSRKIERSGGPLMGPNDERLNGKNAEMVGN--FPLKFLVNLVKLTKLIDIKKGL 468

  Fly   598 IQRLNKMNGTAELAMGDMISHDENGDRHRRQIAVNFQRQYAFNIVTIERINAELMFELTKVQELS 662
            |::||::|..||:       .:...|::.:.    ||.:||..|:.:|.:|..:...:..:|:..
 Worm   469 IRQLNELNADAEI-------QNMTSDKYSKA----FQEKYAKTIIDLEHVNQNIDINMNGIQDHH 522

  Fly   663 SSLTRNPNVQAMISPTYLREECRAKASQTVDDINKGM-VKNTRMIKLLKDLTTLLIVTQNLGGDC 726
            ...:.|....:.:.|..:|:.|..:|.:.|:..|:|: |:|...:.|::.||.:|:..:.:|..
 Worm   523 MYFSSNDISTSNMKPEAVRQMCSQQAGRFVEHCNQGLNVENVHALTLIQSLTAVLLQVRTMGTQ- 586

  Fly   727 EVSEVN-EVLEGCLEEVRSNLICSENREVFQMSVQ 760
            ::|.|: :.|...:.|:|: .|...|...||..|:
 Worm   587 KISAVDLQSLGDAISEIRT-AIHPRNVAFFQDYVE 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mip130	NP_569958.2	DIRP	311..419	CDD:284095	43/108 (40%)
lin-9	NP_001023016.1	DIRP	226..332	CDD:284095	43/108 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156314
Domainoid	1	1.000	83	1.000	Domainoid score	I5373
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H35252
Inparanoid	1	1.050	84	1.000	Inparanoid score	I3747
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D279992at33208
OrthoFinder	1	1.000	-	-		FOG0005813
OrthoInspector	1	1.000	-	-		oto19692
orthoMCL	1	0.900	-	-		OOG6_106727
Panther	1	1.100	-	-	LDO	PTHR21689
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2615
SonicParanoid	1	1.000	-	-		X4787
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.930