DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment arm and NRK1

DIOPT Version :9

Sequence 1:	NP_001259149.1	Gene:	arm / 31151	FlyBaseID:	FBgn0000117	Length:	843	Species:	Drosophila melanogaster
Sequence 2:	NP_014270.1	Gene:	NRK1 / 855594	SGDID:	S000005073	Length:	240	Species:	Saccharomyces cerevisiae

Alignment Length:	223	Identity:	37/223 - (16%)
Similarity:	69/223 - (30%)	Gaps:	64/223 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 TMSHNNQYNPPDLPPMVSAKEQTLMW------------------QQNSYLGDSGIHSGAV----- 51
            |:.|.:.:...|....|.||.....|                  :|...:....||:..|
Yeast    34 TLIHEDDFYKHDNEVPVDAKYNIQNWDSPEALDFKLFGKELDVIKQTGKIATKLIHNNNVDDPFT 98

  Fly    52 -------------TQVPSLSGKEDEEMEGDPLMFDLDTGFPQNFTQDQVDDMN-------QQLSQ 96
                         .:..|::..:.|.:..|..|...:||..:.|      |:.       :.|.:
Yeast    99 KFHIDRQVWDELKAKYDSINDDKYEVVIVDGFMIFNNTGISKKF------DLKILVRAPYEVLKK 157

  Fly    97 TRSQRVRAAMFPETLEEGIE-IPSTQFDPQQPTAVQRLSEPSQMLKHAVVNLINYQDDAELATRA 160
            .|:.|           :|.: :.|...||  |.........|....||.: .:|...:..|..|.
Yeast   158 RRASR-----------KGYQTLDSFWVDP--PYYFDEFVYESYRANHAQL-FVNGDVEGLLDPRK 208

  Fly   161 IPELIKLLNDEDQVVVSQAAMMVHQLSK 188
            ...:.:.:||:|..:....:.:..::.|
Yeast   209 SKNIKEFINDDDTPIAKPLSWVCQEILK 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
arm	NP_001259149.1	Adaptin_N	<150..>314	CDD:331138	6/39 (15%)
		armadillo repeat	161..186	CDD:293788	3/24 (13%)
		armadillo repeat	193..231	CDD:293788
		armadillo repeat	238..270	CDD:293788
		armadillo repeat	278..314	CDD:293788
		armadillo repeat	320..355	CDD:293788
		Arm	361..398	CDD:278915
		armadillo repeat	362..397	CDD:293788
		armadillo repeat	410..435	CDD:293788
		Arm	439..481	CDD:278915
		armadillo repeat	443..481	CDD:293788
		armadillo repeat	490..525	CDD:293788
		Arm	597..636	CDD:278915
		armadillo repeat	600..636	CDD:293788
		armadillo repeat	641..675	CDD:293788
NRK1	NP_014270.1	NRK1	8..198	CDD:238982	30/183 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0572
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900