DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment arm and PUB17

DIOPT Version :9

Sequence 1:NP_001259149.1 Gene:arm / 31151 FlyBaseID:FBgn0000117 Length:843 Species:Drosophila melanogaster
Sequence 2:NP_174228.1 Gene:PUB17 / 839808 AraportID:AT1G29340 Length:729 Species:Arabidopsis thaliana


Alignment Length:535 Identity:112/535 - (20%)
Similarity:175/535 - (32%) Gaps:190/535 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    69 PLMFDLDTGFPQNFTQDQVDDMNQQLSQTRSQRVRAAMFPETLEEG-IEIPSTQFDPQQPTAVQR 132
            |:..||.|. |...:..|..|.|.              ....:||| ...|.|.         |.
plant   312 PISLDLMTD-PVIISTGQTYDRNS--------------IARWIEEGHCTCPKTG---------QM 352

  Fly   133 LSE----PSQMLKHAVVNL-----INYQDD----------AELATRAIPE--------LIKLLND 170
            |.:    |::.||:.:|..     |:|:.:          :.|.|:|..|        |||.|.|
plant   353 LMDSRIVPNRALKNLIVQWCTASGISYESEFTDSPNESFASALPTKAAVEANKATVSILIKYLAD 417

  Fly   171 EDQVVVSQAAMMVHQLSKKEASRHAIMNSPQMVAALVRAISNSNDLESTKAAVGTLHNLSHHRQG 235
            ..|...:.||..:..|:|......|.:.....:..|.|.:::.|.:....:....| |||.:.:.
plant   418 GSQAAQTVAAREIRLLAKTGKENRAYIAEAGAIPHLCRLLTSENAIAQENSVTAML-NLSIYEKN 481

  Fly   236 LLAIFKSGG-IPALVKLLSS--PVE-----SVLFYAITTLHNLLLHQDGSKMAVRLAGGLQKMVT 292
            ...|.:.|. :.::|.:|.|  .||     :...::::.:|..                      
plant   482 KSRIMEEGDCLESIVSVLVSGLTVEAQENAAATLFSLSAVHEY---------------------- 524

  Fly   293 LLQRNNVKFLAIVTDCLQILAYGNQESKLIILASGGPNELVRIMRSYDYEKLLWTTSRVLKVLSV 357
                  .|.:|||..|::.||        ::|.:|.|.      ...|....|:.       ||.
plant   525 ------KKRIAIVDQCVEALA--------LLLQNGTPR------GKKDAVTALYN-------LST 562

  Fly   358 CSSNKPAIVDAGGMQALAMHLGNMSPRLVQNCLWTLRNLSDAATKVEGLEALL--QSL-VQVLGS 419
            ...|...:::.||:.:|...|.|                ...|.:..|..|||  ||| .:.:|.
plant   563 HPDNCSRMIEGGGVSSLVGALKN----------------EGVAEEAAGALALLVRQSLGAEAIGK 611

  Fly   420 TDVNVVTCAAGILSNLTCNNQRNKATVCQVGGVDALVRTIINAGDREEITEPAVCALRHLTSRHV 484
            .|    :..||::..:.|...|.|                          |.||.||        
plant   612 ED----SAVAGLMGMMRCGTPRGK--------------------------ENAVAAL-------- 638

  Fly   485 DSELAQNAVRLNYGLSVIVKLLHPPSRWPLIKAVIGLIRNLALCPANHAPLREHGAIHHLVRLLM 549
             .||.::.     |.:|..|:|..|       |:.||::.|.......|  |...|      .|.
plant   639 -LELCRSG-----GAAVAEKVLRAP-------AIAGLLQTLLFTGTKRA--RRKAA------SLA 682

  Fly   550 RAFQDTER--QRSSI 562
            |.||..|.  .||.:
plant   683 RVFQRRENAAMRSGV 697

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
armNP_001259149.1 Adaptin_N <150..>314 CDD:331138 37/189 (20%)
armadillo repeat 161..186 CDD:293788 9/32 (28%)
armadillo repeat 193..231 CDD:293788 7/37 (19%)
armadillo repeat 238..270 CDD:293788 8/39 (21%)
armadillo repeat 278..314 CDD:293788 6/35 (17%)
armadillo repeat 320..355 CDD:293788 5/34 (15%)
Arm 361..398 CDD:278915 6/36 (17%)
armadillo repeat 362..397 CDD:293788 5/34 (15%)
armadillo repeat 410..435 CDD:293788 8/27 (30%)
Arm 439..481 CDD:278915 7/41 (17%)
armadillo repeat 443..481 CDD:293788 6/37 (16%)
armadillo repeat 490..525 CDD:293788 8/34 (24%)
Arm 597..636 CDD:278915
armadillo repeat 600..636 CDD:293788
armadillo repeat 641..675 CDD:293788
PUB17NP_174228.1 RING-Ubox_PUB 309..351 CDD:319578 13/62 (21%)
U-box domain, a modified RING finger 311..349 CDD:319578 12/51 (24%)
PLN03200 <403..>563 CDD:215629 40/209 (19%)
armadillo repeat 408..433 CDD:293788 8/24 (33%)
armadillo repeat 441..477 CDD:293788 7/36 (19%)
armadillo repeat 483..518 CDD:293788 7/34 (21%)
HEAT repeat 533..559 CDD:293787 8/39 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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