DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment arm and PUB8

DIOPT Version :9

Sequence 1:	NP_001259149.1	Gene:	arm / 31151	FlyBaseID:	FBgn0000117	Length:	843	Species:	Drosophila melanogaster
Sequence 2:	NP_193866.1	Gene:	PUB8 / 827885	AraportID:	AT4G21350	Length:	374	Species:	Arabidopsis thaliana

Alignment Length:	341	Identity:	79/341 - (23%)
Similarity:	154/341 - (45%)	Gaps:	36/341 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 EIPSTQFDPQQPTAVQRLSEPSQMLKHAVVNLINYQDDAELATRAIPELIKLLNDEDQVVVSQAA 180
            ::|:   |.:.|.:::.:|:|..:......:.::.|...:...|..| :.||...|...::...|
plant     4 DLPN---DFRCPISLEIMSDPVILQSGHTFDRVSIQQWIDSGNRTCP-ITKLPLSETPYLIPNHA 64

  Fly   181 M------MVHQLSKKEASR------HAIMNSPQMVAALV-RAISNSNDLES-TKAAVGTLHNLSH 231
            :      ..| :|.||:||      |:...|..:::.|| ::.||::.||| |:....|..:.|.
plant    65 LRSLILNFAH-VSLKESSRPRTQQEHSHSQSQALISTLVSQSSSNASKLESLTRLVRLTKRDSSI 128

  Fly   232 HRQGLLAIFKSGGIPALVKLLSSPVESVLFYAITTLHNLLLHQDGSKMAVRLAGGLQKMVTLLQR 296
            .|:    :.:||.:.|.:..:.|..:.:...:::.|.||.| :|.:|:.:...|.::::||:|:.
plant   129 RRK----VTESGAVRAALDCVDSCNQVLQEKSLSLLLNLSL-EDDNKVGLVADGVIRRIVTVLRV 188

  Fly   297 NNVKFLAIVTDCLQILAYGNQESKLIILASGGPNELVRIMR-SYDYEKLLWTTSRVLKVLSVCS- 359
            .:....||....|..||........|.......:.||.::| ..|.|:....|:    :.::||
plant   189 GSPDCKAIAATLLTSLAVVEVNKATIGSYPDAISALVSLLRVGNDRERKESATA----LYALCSF 249

  Fly   360 -SNKPAIVDAGGMQALAMHLGNMSPRLVQ--NCLWTLRNLSDAATKVEGLEALLQSLVQVLGSTD 421
             .|:..:||.|.:..|.....:...|.|:  ..|...|...:..:||.|   .::.||.||.:.:
plant   250 PDNRKRVVDCGSVPILVEAADSGLERAVEVLGLLVKCRGGREEMSKVSG---FVEVLVNVLRNGN 311

  Fly   422 VNVVTCAAGILSNLTC 437
            :..:..:..||:.|.|
plant   312 LKGIQYSLFILNCLCC 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
arm	NP_001259149.1	Adaptin_N	<150..>314	CDD:331138	44/177 (25%)
		armadillo repeat	161..186	CDD:293788	6/30 (20%)
		armadillo repeat	193..231	CDD:293788	12/45 (27%)
		armadillo repeat	238..270	CDD:293788	5/31 (16%)
		armadillo repeat	278..314	CDD:293788	9/35 (26%)
		armadillo repeat	320..355	CDD:293788	7/35 (20%)
		Arm	361..398	CDD:278915	9/38 (24%)
		armadillo repeat	362..397	CDD:293788	8/36 (22%)
		armadillo repeat	410..435	CDD:293788	6/24 (25%)
		Arm	439..481	CDD:278915
		armadillo repeat	443..481	CDD:293788
		armadillo repeat	490..525	CDD:293788
		Arm	597..636	CDD:278915
		armadillo repeat	600..636	CDD:293788
		armadillo repeat	641..675	CDD:293788
PUB8	NP_193866.1	Ubox	8..72	CDD:128780	11/64 (17%)
		ARM	173..284	CDD:237987	25/114 (22%)
		armadillo repeat	179..204	CDD:293788	6/24 (25%)
		armadillo repeat	211..248	CDD:293788	7/40 (18%)
		armadillo repeat	294..325	CDD:293788	9/33 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910