DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment arm and PUB22

DIOPT Version :9

Sequence 1:	NP_001259149.1	Gene:	arm / 31151	FlyBaseID:	FBgn0000117	Length:	843	Species:	Drosophila melanogaster
Sequence 2:	NP_190813.1	Gene:	PUB22 / 824410	AraportID:	AT3G52450	Length:	435	Species:	Arabidopsis thaliana

Alignment Length:	417	Identity:	78/417 - (18%)
Similarity:	154/417 - (36%)	Gaps:	98/417 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 PTAVQRLSEPSQMLKHAVVNLINYQD----DAELATRAIP---------ELIKLLNDEDQVVVSQ 178
            |...|.::|......|.:..||  |.    :|......||         |:.||:.:.....::|
plant    50 PVTKQVITETDLTPNHTLRRLI--QSWCTLNASYGIERIPTPKPPICKSEIEKLIKESSSSHLNQ 112

  Fly   179 AAMM--VHQLSKKEASRHAIMNSPQMVAALVRAISNSNDLESTKAAVGTLHNLSHHRQG--LLAI 239
            ...:  :.|:..:..:....:.:.::...|...:|||.|..::.::..:..||:...|.  |...
plant   113 VKCLKRLRQIVSENTTNKRCLEAAEVPEFLANIVSNSVDTYNSPSSSLSSSNLNDMCQSNMLENR 177

  Fly   240 FKSGGIPALVKLLSSPVESVLFY---AITTLHNLLLHQDGSKMAVRLAGGLQKMV-------TLL 294
            |.|.      :.|.....|||::   :.|.|.:||.::.|:.:...|...:|:.:       .||
plant   178 FDSS------RSLMDEALSVLYHLDTSETALKSLLNNKKGTNLVKTLTKIMQRGIYESRAYAALL 236

  Fly   295 QRNNVKFLAIVTDCLQILAYGNQESKLIILASGGPNELVRIMRSYDYEKLLWTTSRVLKVLSVCS 359
                :|.|..|.|.:||:..   |.:|.       .|:::|:......|...:..::|.:.....
plant   237 ----LKKLLEVADPMQIILL---ERELF-------GEVIQILHDQISHKATRSAMQILVITCPWG 287

  Fly   360 SNKPAIVDAGGMQALAMHLGNMSPRLVQNCLWTLRNLSDAATKVEGLEALLQSLVQVLGSTDVNV 424
            .|:...|: ||..::.:.|      |:.:...:.|..|:.|..|  |:.|.|
plant   288 RNRHKAVE-GGTISMIIEL------LMDDTFSSERRNSEMAMVV--LDMLCQ------------- 330

  Fly   425 VTCAAG-----------------ILSNLTCNNQRNKATVCQVG---GVDALVRTIINAGDREEIT 469
              ||.|                 ||......::|....:..||   ...:|::.::..|     .
plant   331 --CAEGRAEFLNHGAAIAVVSKKILRVSQITSERAVRVLLSVGRFCATPSLLQEMLQLG-----V 388

  Fly   470 EPAVCALRHLTSRHVDSELAQNAVRLN 496
            ...:|.:..::..:...|.|:..::|:
plant   389 VAKLCLVLQVSCGNKTKEKAKELLKLH 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
arm	NP_001259149.1	Adaptin_N	<150..>314	CDD:331138	39/190 (21%)
		armadillo repeat	161..186	CDD:293788	6/35 (17%)
		armadillo repeat	193..231	CDD:293788	7/37 (19%)
		armadillo repeat	238..270	CDD:293788	8/34 (24%)
		armadillo repeat	278..314	CDD:293788	10/42 (24%)
		armadillo repeat	320..355	CDD:293788	5/34 (15%)
		Arm	361..398	CDD:278915	7/36 (19%)
		armadillo repeat	362..397	CDD:293788	6/34 (18%)
		armadillo repeat	410..435	CDD:293788	6/41 (15%)
		Arm	439..481	CDD:278915	6/44 (14%)
		armadillo repeat	443..481	CDD:293788	5/40 (13%)
		armadillo repeat	490..525	CDD:293788	1/7 (14%)
		Arm	597..636	CDD:278915
		armadillo repeat	600..636	CDD:293788
		armadillo repeat	641..675	CDD:293788
PUB22	NP_190813.1	Ubox	11..74	CDD:128780	7/25 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000