DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment arm and PUB39

DIOPT Version :9

Sequence 1:	NP_001259149.1	Gene:	arm / 31151	FlyBaseID:	FBgn0000117	Length:	843	Species:	Drosophila melanogaster
Sequence 2:	NP_190366.2	Gene:	PUB39 / 823936	AraportID:	AT3G47820	Length:	531	Species:	Arabidopsis thaliana

Alignment Length:	427	Identity:	86/427 - (20%)
Similarity:	166/427 - (38%)	Gaps:	70/427 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PDLP---PMVSAKEQTLMW---------QQNSYLGDSGIHSGAVTQVPSLSGKEDEEMEGDPLMF 72
            |||.   |.::.|...|.|         :...|....|:....:..:|..||....:.|..|
plant    80 PDLSTVIPNLAMKSTILSWCDRNKMEHPRPPDYAYVEGVVRTRMDSLPPGSGHRIAKSEILP--- 141

  Fly    73 DLDTGFPQNFTQDQVDDMNQQLSQTRSQRVRAAMFPETLEEGIEIPSTQFDP-QQPTAVQRLSEP 136
                  |.....:...|.:..:...|| |.|.::...|     .:|..|..| ...|.:|.....
plant   142 ------PVAENSNSNSDYDSVMGAIRS-RSRTSLSSTT-----SLPLHQTRPINHSTRIQSSFST 194

  Fly   137 SQMLKHAVVNLINYQDDAELATRAIPELIKLLNDEDQVVVSQAAMMVHQLSKKEASRHAIMNSPQ 201
            |           :|.....::... .|:...|...|.:...|..:.:.:.::...:....:.:.:
plant   195 S-----------DYSSFPPMSPEE-EEIYNKLTSVDTIDHEQGLIQLRKTTRSNETTRISLCTDR 247

  Fly   202 MVAALVRAISNSNDLESTKAAVGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPVESVLFYAITT 266
            :::.|...|.:..::..|.|| .::.|||..:...|.|.:||.:|.|:.:|.|.......:.|..
plant   248 ILSLLRSLIVSRYNIVQTNAA-ASIVNLSLEKPNKLKIVRSGFVPLLIDVLKSGSTEAQEHVIGA 311

  Fly   267 LHNLLLHQDGSKMAVRLAGGLQKMVTLLQRNNV----KFLAIVTDCLQILAYGNQESKLIILASG 327
            |.:|.:.:: :||.:.:.|.::.::..|:.:..    :..|:....|.::.  |..|:|:  .:|
plant   312 LFSLAVEEE-NKMVIGVLGAVEPLLHALRSSESERARQDAALALYHLSLIP--NNRSRLV--KAG 371

  Fly   328 GPNELVRIMRSYDYEKLLWTTSRVLKV---LSVCSSNKPAIVDAGGMQALAMHL----GNMSPRL 385
            ....::.::||.:      :.||:|.:   |:.||..|.|::|...:..|...|    |..|...
plant   372 AVPMMLSMIRSGE------SASRILLLLCNLAACSEGKGAMLDGNAVSILVGKLRESGGAESDAA 430

  Fly   386 V-QNCLWTLRNLSDAATKVEGL------EALLQSLVQ 415
            . :||:..|..||....:..||      |.:|..:|:
plant   431 ARENCVGALLTLSVGNMRFRGLASEAGAEEILTEIVE 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
arm	NP_001259149.1	Adaptin_N	<150..>314	CDD:331138	30/167 (18%)
		armadillo repeat	161..186	CDD:293788	4/24 (17%)
		armadillo repeat	193..231	CDD:293788	7/37 (19%)
		armadillo repeat	238..270	CDD:293788	9/31 (29%)
		armadillo repeat	278..314	CDD:293788	6/39 (15%)
		armadillo repeat	320..355	CDD:293788	7/37 (19%)
		Arm	361..398	CDD:278915	11/41 (27%)
		armadillo repeat	362..397	CDD:293788	10/39 (26%)
		armadillo repeat	410..435	CDD:293788	2/6 (33%)
		Arm	439..481	CDD:278915
		armadillo repeat	443..481	CDD:293788
		armadillo repeat	490..525	CDD:293788
		Arm	597..636	CDD:278915
		armadillo repeat	600..636	CDD:293788
		armadillo repeat	641..675	CDD:293788
PUB39	NP_190366.2	Ubox	35..98	CDD:128780	6/17 (35%)
		SRP1	203..>344	CDD:227396	27/143 (19%)
		armadillo repeat	281..316	CDD:293788	10/34 (29%)
		PLN03200	290..>359	CDD:215629	13/69 (19%)
		armadillo repeat	322..354	CDD:293788	5/31 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910