DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment arm and PUB25

DIOPT Version :9

Sequence 1:	NP_001259149.1	Gene:	arm / 31151	FlyBaseID:	FBgn0000117	Length:	843	Species:	Drosophila melanogaster
Sequence 2:	NP_566632.1	Gene:	PUB25 / 821472	AraportID:	AT3G19380	Length:	421	Species:	Arabidopsis thaliana

Alignment Length:	382	Identity:	82/382 - (21%)
Similarity:	137/382 - (35%)	Gaps:	108/382 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 GIEIPSTQFDPQQPTAVQRLSEPSQML--KH--------AVVNLINYQDDAE------LATRAIP 162
            |:|...|...|..||:|:.|...:..:  .|        |:..|..:..|::      .|..|..
plant    89 GVERIPTPKQPADPTSVRALLSQASAITGTHVSVRSRAAALRRLRGFARDSDKNRVLIAAHNATE 153

  Fly   163 ELIKLLNDE--DQVVVSQAAMMVHQLSKKEASRH-AIMNSPQMVAALVRAISNSNDLESTKAAVG 224
            .|||:|..|  ...:||::..::..|...|.::. :|.:.|..|..|.|.:.:|:......||
plant   154 ILIKILFSETTSSELVSESLALLVMLPITEPNQFVSISSDPGRVEFLTRLLFDSSIETRVNAA-- 216

  Fly   225 TLHNLSHHRQGLLAIFKSGGIPALVKLLSSPVESVLFYAITTLHNLLLHQDGSKMAVRLAGGLQK 289
                      .|:.|..:|...|.:|...|..|||....:..|.|.:    .|:.|:::  |::.
plant   217 ----------ALIEIVSTGTKSADLKGSISNSESVFEGVLDLLRNPI----SSRRALKI--GIKT 265

  Fly   290 MVTLLQRNNVKFLAIVTDCLQILAYGNQESKLIILASGGPNELV-RIMRSY---DYEKLLWTTSR 350
            :..|....:.:.:||                    .:|.|..|: |:...:   |.|:.|.|...
plant   266 LFALCSVKSTRHIAI--------------------TAGAPEILIDRLAADFDRCDTERALATVEL 310

  Fly   351 VLKVLSVCSSNKPAIVDAGGMQALAMHLGNMSPRLVQNCLWTLRNLSDAATKVEGLEALLQSLVQ 415
            :.:....|:        |.|..||.:      |.||:    |:..:||.||:.
plant   311 LCRTPEGCA--------AFGEHALTV------PLLVK----TILRVSDRATEY------------ 345

  Fly   416 VLGSTDVNVVTCAAGILSNLTCNNQRNKATVCQVGGVDALVRTIINAGDREEITEPA 472
                        |||.|..|....:|.:......|.|..|:..:     :.|.||.|
plant   346 ------------AAGALLALCTAEERWREEAAGAGVVVQLLLMV-----QSECTERA 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
arm	NP_001259149.1	Adaptin_N	<150..>314	CDD:331138	37/172 (22%)
		armadillo repeat	161..186	CDD:293788	7/26 (27%)
		armadillo repeat	193..231	CDD:293788	8/38 (21%)
		armadillo repeat	238..270	CDD:293788	9/31 (29%)
		armadillo repeat	278..314	CDD:293788	5/35 (14%)
		armadillo repeat	320..355	CDD:293788	8/38 (21%)
		Arm	361..398	CDD:278915	8/36 (22%)
		armadillo repeat	362..397	CDD:293788	8/34 (24%)
		armadillo repeat	410..435	CDD:293788	4/24 (17%)
		Arm	439..481	CDD:278915	8/34 (24%)
		armadillo repeat	443..481	CDD:293788	7/30 (23%)
		armadillo repeat	490..525	CDD:293788
		Arm	597..636	CDD:278915
		armadillo repeat	600..636	CDD:293788
		armadillo repeat	641..675	CDD:293788
PUB25	NP_566632.1	Ubox	17..81	CDD:128780
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000