DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment arm and PUB23

DIOPT Version :9

Sequence 1:	NP_001259149.1	Gene:	arm / 31151	FlyBaseID:	FBgn0000117	Length:	843	Species:	Drosophila melanogaster
Sequence 2:	NP_181137.2	Gene:	PUB23 / 818166	AraportID:	AT2G35930	Length:	411	Species:	Arabidopsis thaliana

Alignment Length:	342	Identity:	73/342 - (21%)
Similarity:	124/342 - (36%)	Gaps:	87/342 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   338 SYD---YEKLLWTTSRVLKVLSVCSSNKPAIVDAGGMQALAMHLGNMSP-----RLVQNCLWTLR 394
            :||   .||.|:...:     :.|...|..|.||           :::|     ||:|:  |...
plant    36 TYDRDSIEKWLFAGKK-----NSCPVTKQDITDA-----------DLTPNHTLRRLIQS--WCTL 82

  Fly   395 NLSDAATKVEG-----LEALLQSLVQVLGSTDVNVVTCAAGILSNLTCNNQRNKATVCQVGGVDA 454
            |.|....::..     .::.::.|::...|:..|.|.|... |..:...|..||..:...|..:.
plant    83 NASYGVERIPTPRPPICKSEIEKLIRDSASSHENQVKCLKR-LRQIVSENATNKRCLEAAGVPEF 146

  Fly   455 LVRTIINAGDREEITEPAVCALRHL-TSRHVDSELAQNAVRLNYGLSVIVKLLHPPSRWPLIKAV 518
            |...:.|..:...:|:.|:..|.|| ||..|...|..|....|     |||.|
plant   147 LANIVSNDSENGSLTDEALNLLYHLETSETVLKNLLNNKKDNN-----IVKSL------------ 194

  Fly   519 IGLIRNLALCPANHAPLREHGAIHHLV--RLLMRAFQDTERQRSSIATTGSQQPSAYADGVR-ME 580
                          ..:.:.|.....|  .||::...:......|:    :.:|..:.:.|: ::
plant   195 --------------TKIMQRGMYESRVYATLLLKNILEVADPMQSM----TLKPEVFTEVVQILD 241

  Fly   581 EIV--EGTVGALHILAR---ESHNRALIRQQSVIPIFVRLLFNEIENIQR-------VAAGVLCE 633
            :.:  :.|..|:|||..   ...||....:..||.:.:.||.:|....:|       |...:||:
plant   242 DRISQKATKAAMHILVNICPWGRNRHKAVEAGVISVIIELLMDESFTSERRGPEMAMVVLDLLCQ 306

  Fly   634 LAADKEG-AEIIEQEGA 649
            .|   || ||.:....|
plant   307 CA---EGRAEFLNHGAA 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
arm	NP_001259149.1	Adaptin_N	<150..>314	CDD:331138
		armadillo repeat	161..186	CDD:293788
		armadillo repeat	193..231	CDD:293788
		armadillo repeat	238..270	CDD:293788
		armadillo repeat	278..314	CDD:293788
		armadillo repeat	320..355	CDD:293788	5/19 (26%)
		Arm	361..398	CDD:278915	10/41 (24%)
		armadillo repeat	362..397	CDD:293788	10/39 (26%)
		armadillo repeat	410..435	CDD:293788	6/24 (25%)
		Arm	439..481	CDD:278915	11/42 (26%)
		armadillo repeat	443..481	CDD:293788	9/38 (24%)
		armadillo repeat	490..525	CDD:293788	6/34 (18%)
		Arm	597..636	CDD:278915	11/45 (24%)
		armadillo repeat	600..636	CDD:293788	10/42 (24%)
		armadillo repeat	641..675	CDD:293788	3/9 (33%)
PUB23	NP_181137.2	Ubox	16..79	CDD:128780	14/60 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000