DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment arm and prune2

DIOPT Version :9

Sequence 1:NP_001259149.1 Gene:arm / 31151 FlyBaseID:FBgn0000117 Length:843 Species:Drosophila melanogaster
Sequence 2:NP_001104624.2 Gene:prune2 / 556822 ZFINID:ZDB-GENE-050309-222 Length:321 Species:Danio rerio


Alignment Length:250 Identity:48/250 - (19%)
Similarity:89/250 - (35%) Gaps:71/250 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   109 ETLEEGIEIPSTQFDPQQPTAV------------QRLSEP--SQMLKHAVVNLINYQDDAELATR 159
            :|.|..:.....:..|..||::            ::||.|  |..|..:..:|.:..||.:    
Zfish     3 QTYESKMSFEGAESRPAPPTSLPLQGQGGVSSQRKKLSAPRISLSLDQSEDDLFDTPDDLD---- 63

  Fly   160 AIPELIKLLNDEDQVVVSQAAMMVHQLSKKE--ASRHAIMNSPQMVAALVRAISNSNDLESTKAA 222
                    :|.:|.....:|....|::..:|  ||:.   :|.:.....:...|...:.:.:|..
Zfish    64 --------INVDDLDTPDEADYTDHEIDWEEPQASQR---DSVKETVESIPTYSAEEERQDSKLW 117

  Fly   223 VGTLHNLSHHRQGLLAI-----------FKSGGIPALVKLLS------------SPVESVLFYAI 264
            ...:.....||..:.:|           :.|.|..|::...:            ..:|::..|.|
Zfish   118 RTVIIGEQEHRINMKSIEPYQKVISHGGYYSNGANAIIVFAACFLPDSDREDYHEIMENLFLYVI 182

  Fly   265 TTLHNLLLHQDGSKMAVRLAG--------GLQ------KMVTLLQRNNVKFLAIV 305
            :|| .|::.:|  .|.|.|.|        ||.      :|:....|.|:|...||
Zfish   183 STL-ELMVAED--YMIVYLNGATPHRRMPGLNWLKRCYQMIDRRLRKNLKSFIIV 234

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
armNP_001259149.1 Adaptin_N <150..>314 CDD:331138 36/194 (19%)
armadillo repeat 161..186 CDD:293788 4/24 (17%)
armadillo repeat 193..231 CDD:293788 3/37 (8%)
armadillo repeat 238..270 CDD:293788 9/54 (17%)
armadillo repeat 278..314 CDD:293788 11/41 (27%)
armadillo repeat 320..355 CDD:293788
Arm 361..398 CDD:278915
armadillo repeat 362..397 CDD:293788
armadillo repeat 410..435 CDD:293788
Arm 439..481 CDD:278915
armadillo repeat 443..481 CDD:293788
armadillo repeat 490..525 CDD:293788
Arm 597..636 CDD:278915
armadillo repeat 600..636 CDD:293788
armadillo repeat 641..675 CDD:293788
prune2NP_001104624.2 BNIP2 35..150 CDD:372150 22/129 (17%)
CRAL_TRIO_2 152..283 CDD:372686 19/85 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0572
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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