DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment arm and nmrk1

DIOPT Version :9

Sequence 1:	NP_001259149.1	Gene:	arm / 31151	FlyBaseID:	FBgn0000117	Length:	843	Species:	Drosophila melanogaster
Sequence 2:	XP_017209594.1	Gene:	nmrk1 / 541321	ZFINID:	ZDB-GENE-050320-8	Length:	213	Species:	Danio rerio

Alignment Length:	100	Identity:	23/100 - (23%)
Similarity:	42/100 - (42%)	Gaps:	33/100 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   629 GVLCELAADKEGAEIIEQEGATGPLTDLLHSRNE-GVATYAAAVLFRMSEDKP-------QDYK- 684
            |||| |::..|.|::|:.:|.:..:...:..::. ||:      ||...:||.       |..|
Zfish    16 GVLC-LSSFAESADVIKFKGESATMKCHISDKDAMGVS------LFTRHKDKQEVLYYFIQSNKL 73

  Fly   685 ----------------KRLSIELTNSLLREDNNIW 703
                            |.|::::.| |.:||...:
Zfish    74 TIKPTHEGRVEAKFDGKTLTVDILN-LQKEDTGAY 107

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
arm	NP_001259149.1	Adaptin_N	<150..>314	CDD:331138
		armadillo repeat	161..186	CDD:293788
		armadillo repeat	193..231	CDD:293788
		armadillo repeat	238..270	CDD:293788
		armadillo repeat	278..314	CDD:293788
		armadillo repeat	320..355	CDD:293788
		Arm	361..398	CDD:278915
		armadillo repeat	362..397	CDD:293788
		armadillo repeat	410..435	CDD:293788
		Arm	439..481	CDD:278915
		armadillo repeat	443..481	CDD:293788
		armadillo repeat	490..525	CDD:293788
		Arm	597..636	CDD:278915	5/6 (83%)
		armadillo repeat	600..636	CDD:293788	5/6 (83%)
		armadillo repeat	641..675	CDD:293788	7/34 (21%)
nmrk1	XP_017209594.1	V-set	34..131	CDD:311561	15/80 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0572
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900