DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment arm and CG11593

DIOPT Version :9

Sequence 1:	NP_001259149.1	Gene:	arm / 31151	FlyBaseID:	FBgn0000117	Length:	843	Species:	Drosophila melanogaster
Sequence 2:	NP_001261392.1	Gene:	CG11593 / 38477	FlyBaseID:	FBgn0035488	Length:	484	Species:	Drosophila melanogaster

Alignment Length:	329	Identity:	66/329 - (20%)
Similarity:	108/329 - (32%)	Gaps:	110/329 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 NPPDLPPMVSAKEQTLMWQQNSYLGDSGIHSGAVTQVPSLSGKEDEE---MEGDPLMFDLDTGFP 79
            |.||:   :|::...   ..:.||.....:..:|:.:|:.:||:.:.   :.|...:..||:...
  Fly   161 NSPDI---LSSESDA---DVSQYLAAVESNFQSVSLMPNGNGKKSKRSTALPGGEDISSLDSISN 219

  Fly    80 QNFTQDQVDDMNQQLSQTRSQRVRAAMFP-ETLEEGIEIPSTQFDPQQPTAVQRLSEPSQMLKHA 143
            .:|..|  :|:...|         |::.| .:|.:|::......|.:.|..
  Fly   220 HSFDDD--EDIEHNL---------ASLSPSSSLIDGLDGEDDDDDCEGPEL-------------- 259

  Fly   144 VVNLINYQDDAE------LATRAIPELIKLLNDEDQVVVSQAAMMVHQLSKKEASRHAIMNSPQM 202
               |.::.||.|      |||...|                         ...||..|....||.
  Fly   260 ---LPDHDDDLELDLEFGLATTPTP-------------------------NAPASATAASTLPQY 296

  Fly   203 VAALVRAISNSNDLESTKAAVGTLHN------------LSHHRQGLLAIFKSGGIPALVKL---- 251
            .||..|  .:|.:.:......|....            |||  .|.|   ||||..|:|..
  Fly   297 TAAEER--RDSRNWQKITLPDGRTREIDMRVIEPYKRVLSH--GGYL---KSGGQNAIVIFCACH 354

  Fly   252 --------LSSPVESVLFYAITTLHNLLLHQDGSKMAVRLAGGLQKMVTLLQRNNVKFLAIVTDC 308
                    .|..::::..|.:.||..|:   ....:.:.|.||       ..|.||.....:..|
  Fly   355 LPDRSRADYSYVMDNLFLYVVKTLEQLV---TDDYVLIYLHGG-------SNRRNVPPFPWLKRC 409

  Fly   309 LQIL 312
            .|:|
  Fly   410 YQLL 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
arm	NP_001259149.1	Adaptin_N	<150..>314	CDD:331138	42/193 (22%)
		armadillo repeat	161..186	CDD:293788	1/24 (4%)
		armadillo repeat	193..231	CDD:293788	9/49 (18%)
		armadillo repeat	238..270	CDD:293788	10/43 (23%)
		armadillo repeat	278..314	CDD:293788	9/35 (26%)
		armadillo repeat	320..355	CDD:293788
		Arm	361..398	CDD:278915
		armadillo repeat	362..397	CDD:293788
		armadillo repeat	410..435	CDD:293788
		Arm	439..481	CDD:278915
		armadillo repeat	443..481	CDD:293788
		armadillo repeat	490..525	CDD:293788
		Arm	597..636	CDD:278915
		armadillo repeat	600..636	CDD:293788
		armadillo repeat	641..675	CDD:293788
CG11593	NP_001261392.1	BNIP2	<293..342	CDD:289278	13/55 (24%)
CG11593	NP_001261392.1	CRAL_TRIO_2	345..475	CDD:290435	16/79 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0572
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900