DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment arm and CG13326

DIOPT Version :9

Sequence 1:	NP_001259149.1	Gene:	arm / 31151	FlyBaseID:	FBgn0000117	Length:	843	Species:	Drosophila melanogaster
Sequence 2:	NP_610838.1	Gene:	CG13326 / 36439	FlyBaseID:	FBgn0033794	Length:	867	Species:	Drosophila melanogaster

Alignment Length:	603	Identity:	109/603 - (18%)
Similarity:	196/603 - (32%)	Gaps:	178/603 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 PETLEEGIEIPSTQFDPQQPTAVQRLSEPSQMLKHAVVNLINYQDDAELATRAIPELIKLLNDED 172
            ||..:. ||:.:|....::.|   :|.....:....|..:.|:.|...|..|.  .:|.:..:..
  Fly   272 PEAADV-IEVLATALRSEKMT---KLFFEQNLFDQVVEQVRNHMDLMPLEMRC--TIISIFAETA 330

  Fly   173 QVVVSQAAMMVHQLSKKEASRHAIM-NSPQMVAALVRAISNSNDLESTKAAVGTLHNLSHHRQGL 236
            |  ..|....:|:....:.....:| |.|...|.:::.                ||.:|||.:.|
  Fly   331 Q--YEQFLPRMHKAEIADMFLTCLMQNKPAPAAYVIQG----------------LHRMSHHPEAL 377

  Fly   237 ---LAIFKSGGIPALVKLLSSPVESVLFYAITTLHNLLLHQDGSKMAVRLAGGLQKMVTLLQRNN 298
               :|.::.|.|..||.:|.||..::          ....|.|..::..|....::....||..:
  Fly   378 RRIVAAYQEGAIRKLVAILMSPDVAI----------KAREQAGEFLSRLLVAAFRETAAQLQEQD 432

  Fly   299 VKFLAIVTDCLQILAYGNQESKLIILASGGPNELVRIMRSYDYEKLLWTTSRVLKVLSVCSSNKP 363
            :   |:|...              ::|.|.|.      .|.|...||.|   :::.|:.....:.
  Fly   433 I---AVVLTA--------------VIAQGQPT------LSIDLILLLLT---IIESLAQKEEYRT 471

  Fly   364 AIVDAGGMQALAMHLGNMSPR------LVQN---CLWTLRNLSDAATKVEGLEALLQSLVQVLGS 419
            .:   |...:|...|..:..|      ||.|   ||.||  :.:|..:    |.||.:.:
  Fly   472 IL---GEYSSLTEQLAQLLMRSFAHSILVNNIFRCLCTL--IDEAPVR----ETLLANYI----- 522

  Fly   420 TDVNVVTCAAGILSNLTCNNQRNKATVCQVGGVDALVRTIINAGDRE---EITEPAVCALRHLTS 481
              |:.:..|...||||...:..|  .:.|....:..:...|:.|..|   :..:.|.|.
  Fly   523 --VSSMKRALKSLSNLVKTSVTN--FILQTTRFNEFIDAYIDRGIMEVLLDFQKHAFCI------ 577

  Fly   482 RHVDSELAQNAVRLNYGLSVIVKLLHPPSRW-PLIKAVIGLIRNLALCPANHAPLREHGAIHHLV 545
                                        |.| |.|:::      |:.||.....:|.
  Fly   578 ----------------------------STWGPAIESI------LSKCPTMKFAIRN-------- 600

  Fly   546 RLLMRAFQDTERQRSSIATTGSQ---QPSAYADGVRMEEIVEGTVGALHILARESHNRALIRQQS 607
               ...|.|        .|.|..   ....:.|..:.::|:......|..:...:.:|....|..
  Fly   601 ---CLTFTD--------ITAGKDFYVSRRKFEDFRKFQDILRNDCSPLDAVLVMNFDRPKPNQND 654

  Fly   608 VIPIFVRLLFNEIENIQRVAAGVLCELAADKEGAEIIEQEGATGPLTDLLHSRNEGVATYAAAVL 672
            ||.:.:|.|            ..:.:|..| :|....::.|... |...|.:.|:.:|.:...
  Fly   655 VIAVPLRCL------------STITDLPGD-QGWGYCKRPGDNN-LPQYLEALNQTLAMHGLV-- 703

  Fly   673 FRMSEDKPQDYKKRLSIE 690
                 :.|:..::.:..|
  Fly   704 -----ENPERVRRTIDFE 716

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
arm	NP_001259149.1	Adaptin_N	<150..>314	CDD:331138	32/167 (19%)
		armadillo repeat	161..186	CDD:293788	4/24 (17%)
		armadillo repeat	193..231	CDD:293788	6/38 (16%)
		armadillo repeat	238..270	CDD:293788	8/31 (26%)
		armadillo repeat	278..314	CDD:293788	5/35 (14%)
		armadillo repeat	320..355	CDD:293788	8/34 (24%)
		Arm	361..398	CDD:278915	11/45 (24%)
		armadillo repeat	362..397	CDD:293788	11/43 (26%)
		armadillo repeat	410..435	CDD:293788	5/24 (21%)
		Arm	439..481	CDD:278915	7/44 (16%)
		armadillo repeat	443..481	CDD:293788	6/40 (15%)
		armadillo repeat	490..525	CDD:293788	4/35 (11%)
		Arm	597..636	CDD:278915	7/38 (18%)
		armadillo repeat	600..636	CDD:293788	7/35 (20%)
		armadillo repeat	641..675	CDD:293788	5/33 (15%)
CG13326	NP_610838.1	EDR1	<759..799	CDD:291079
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2332
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.940