Protein Alignment arm and Atcay

DIOPT Version :10

• Sequence 1: NP_476665.2
• Gene: arm / 31151
• FlyBaseID: FBgn0000117
• Length: 843
• Species: Drosophila melanogaster
• Sequence 2: NP_848777.1
• Gene: Atcay / 16467
• MGIID: 2448730
• Length: 372
• Species: Mus musculus
• Alignment Length: 292
• Identity: 62/292 - (21%)
• Similarity: 107/292 - (36%)
• Gaps: 94/292 - (32%)

  Fly    39 SYLGDSGIHSGAVTQV-PSLSGKEDEEMEGDPLMFD-LDTGFPQNFTQDQVDDMNQQLSQTRSQR 101
            |.|..||.|....|.| |.::...|:. ||..|..| |||
Mouse    49 STLNLSGAHRKRKTLVAPEINISLDQS-EGSLLSDDFLDT------------------------- 87

  Fly   102 VRAAMFPETLEEGIEIPSTQFDPQQPTAVQRLSEPSQMLKHAVVNLINYQDDAELAT-RAIP-EL 164
                  |:.|:..::...|   |.:..:::.|...         |.:.::||..:|| :.:| :.
Mouse    88 ------PDDLDINVDDIET---PDETDSLEFLGNG---------NELEWEDDTPVATAKNMPGDS 134

  Fly   165 IKLLND---EDQVVVSQAAMMVHQLSKKEASRHAIMNSPQMVAALVRAISNSNDLESTKAAVGTL 226
            ..|..|   ||....:........:.::|   |.|                  ||...:..:..:
Mouse   135 ADLFGDGSAEDGSAANGRLWRTVIIGEQE---HRI------------------DLHMIRPYMKVV 178

  Fly   227 HNLSHHRQGLLAI--FKSGGIPALVKLLSSP-----VESVLFYAITTLHNL------LLHQDGSK 278
            .:..::.:||.||  |.:..:|.    .|||     :|::..|.|::|..|      :::.:|:.
Mouse   179 THGGYYGEGLNAIIVFAACFLPD----SSSPDYHYIMENLFLYVISSLELLVAEDYMIVYLNGAT 239

  Fly   279 MAVRL--AGGLQK---MVTLLQRNNVKFLAIV 305
            ...|:  .|.|:|   |:....|.|:|.|.||
Mouse   240 PRRRMPGIGWLKKCYHMIDRRLRKNLKSLIIV 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
arm	NP_476665.2	CTNNAbd_dArm	85..159	CDD:439243	10/74 (14%)
		Adaptin_N	<150..>314	CDD:396262	40/179 (22%)
		armadillo repeat	161..186	CDD:293788	5/28 (18%)
		armadillo repeat	193..231	CDD:293788	4/37 (11%)
		armadillo repeat	238..270	CDD:293788	11/38 (29%)
		armadillo repeat	278..314	CDD:293788	11/33 (33%)
		armadillo repeat	320..355	CDD:293788
		Arm	361..398	CDD:425727
		armadillo repeat	362..397	CDD:293788
		armadillo repeat	410..435	CDD:293788
		Arm	439..481	CDD:425727
		armadillo repeat	443..481	CDD:293788
		armadillo repeat	490..525	CDD:293788
		Arm	597..636	CDD:425727
		armadillo repeat	600..636	CDD:293788
		armadillo repeat	641..675	CDD:293788
Atcay	NP_848777.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..58		4/8 (50%)
		BNIP2	59..187	CDD:463609	31/192 (16%)
		Required for interaction with KLC1. /evidence=ECO:0000269|PubMed:19861499	115..120		0/4 (0%)
		CRAL_TRIO_2	189..325	CDD:463965	24/87 (28%)
		Mediates interaction with GLS. /evidence=ECO:0000250	190..372		24/86 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	329..372