DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment trr and SET3

DIOPT Version :9

Sequence 1:	NP_726773.2	Gene:	trr / 31149	FlyBaseID:	FBgn0023518	Length:	2431	Species:	Drosophila melanogaster
Sequence 2:	NP_012954.3	Gene:	SET3 / 853900	SGDID:	S000001737	Length:	751	Species:	Saccharomyces cerevisiae

Alignment Length:	167	Identity:	42/167 - (25%)
Similarity:	65/167 - (38%)	Gaps:	42/167 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly  2273 QFVHSKSSQYKKMKQEWRNNVYLARSK----IQGLGLYAARDIEKHTMIIEYIGEVIRTEVSEIR 2333
            |:.|   ..:|.:..|.:....:|.|:    ...||:|..:|..|...|.|.:||:       ..
Yeast   304 QYPH---KTFKSVSIEVKPYADIAYSRTYPGFTKLGVYLKKDCIKGDFIQEILGEL-------DF 358

  Fly  2334 EKQYESKNRGIY----------MFRLDEDRVVDATLSGGLARYINHSCNPNCVTEIVEV---DRD 2385
            .|.|.:..|..|          :|.......:||.|||...||:..||.||  .|:|.:   |.|
Yeast   359 YKNYLTDPRNHYRIWGTAKRRVIFHSHWPIYIDARLSGNSTRYLRRSCQPN--VELVTIKLQDTD 421

  Fly  2386 -------------VRIIIFAKRKIYRGEELSYDYKFD 2409
                         ::.::.|.|.|...|||...:::|
Yeast   422 NRNDKSSGRKSSRIKFVLRALRDISEDEELYIKWQWD 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trr	NP_726773.2	PHA03255	184..>320	CDD:165513
		ePHD2_KMT2C_like	1898..2002	CDD:277136
		FYRN	2068..2118	CDD:283589
		FYRC	2126..2215	CDD:197781
		SET	<2266..2431	CDD:225491	42/167 (25%)
		SET	2291..2413	CDD:214614	38/149 (26%)
		PostSET	2415..2431	CDD:214703
SET3	NP_012954.3	PHD_MLL5	119..163	CDD:277025
SET3	NP_012954.3	SET	217..722	CDD:225491	42/167 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4489
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940