DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trr and TBRG1

DIOPT Version :9

Sequence 1:	NP_726773.2	Gene:	trr / 31149	FlyBaseID:	FBgn0023518	Length:	2431	Species:	Drosophila melanogaster
Sequence 2:	NP_116200.2	Gene:	TBRG1 / 84897	HGNCID:	29551	Length:	411	Species:	Homo sapiens

Alignment Length:	179	Identity:	53/179 - (29%)
Similarity:	91/179 - (50%)	Gaps:	21/179 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly  2066 VGNMTFLNVGQLLPHQLEAFHTPHYIYPIGYKVSRYYWCVRRPNRRCRYICSIAEAGCKPEFRIQ 2130
            :|.:|..::|:::..: ..||....|||:||..:|.|..::.|:::|.|.|.|.:.|.:|:|.|.
Human   187 LGGLTVYSLGEIITDR-PGFHDESAIYPVGYCSTRIYASMKCPDQKCLYTCQIKDGGVQPQFEIV 250

  Fly  2131 VQDAGDKEPEREFRGSSPSAVWQQILQPI-TRLRKVHKWLQLFPQHISGEDLFGLTEPAIVRILE 2194
            .:|    :|:.....||..|...::|:.| |.:.|:..  .|.|   :|.|.||.:.|||..:::
Human   251 PED----DPQNAIVSSSADACHAELLRTISTTMGKLMP--NLLP---AGADFFGFSHPAIHNLIQ 306

  Fly  2195 SLPGIETLTDYRF------KYGRNPLLEFPLAINPSGAART-EPKQRQL 2236
            |.||.....:|::      |.|...|   |..:..:.||.: |..|||:
Human   307 SCPGARKCINYQWVKFDVCKPGDGQL---PEGLPENDAAMSFEAFQRQI 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trr	NP_726773.2	PHA03255	184..>320	CDD:165513
		ePHD2_KMT2C_like	1898..2002	CDD:277136
		FYRN	2068..2118	CDD:283589	15/49 (31%)
		FYRC	2126..2215	CDD:197781	26/95 (27%)
		SET	<2266..2431	CDD:225491
		SET	2291..2413	CDD:214614
		PostSET	2415..2431	CDD:214703
TBRG1	NP_116200.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..29
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	119..146
		FYRN	189..238	CDD:283589	15/49 (31%)
		FYRC	244..319	CDD:283590	25/83 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810