Protein Alignment trr and EFS

DIOPT Version :10

• Sequence 1: NP_726773.2
• Gene: trr / 31149
• FlyBaseID: FBgn0023518
• Length: 2431
• Species: Drosophila melanogaster
• Sequence 2: NP_177854.6
• Gene: EFS / 844066
• AraportID: AT1G77300
• Length: 1805
• Species: Arabidopsis thaliana
• Alignment Length: 1233
• Identity: 222/1233 - (18%)
• Similarity: 405/1233 - (32%)
• Gaps: 450/1233 - (36%)

  Fly  1317 YIQGA--ASGTGHVITSTGQGVTL------GGVGA------STGASSSPMLKKRVRKFSKVEEDH 1367
            |::.|  ..|.|.::.|....:|.      ||:.:      :...:.:|.| |.||: .:::.|.
plant   265 YLEDAIDIEGNGTIVVSPSLAITEMLNNDDGGLCSHDLNKITVTETINPDL-KLVRE-DRLDTDL 327

  Fly  1368 DAFTEKLL-THIRQMQPLQVLEPHLNRNFHFLIGSNETSGGGSPASMSSAASAGSSSAGGGKLKG 1431
            ....||:| .|:                           |..|..|..:|.|..:..|...:.:.
plant   328 SVMNEKMLKNHV---------------------------GDSSSESAVAALSMNNGMAADLRAEN 365

  Fly  1432 GSRGWPLSRHLEGLED----CDGTVLGRY------GRVNLPGIPSLYDSERFGGSRGLVGGSART 1486
            .|:..|:......:|.    .|.:::..:      |.:.:....:..:..|.....|.:||...:
plant   366 FSQSSPIDEKTLDMEANSPITDSSLIWNFPLNFGSGGIEVCNPENAVEPLRIVDDNGRIGGEVAS 430

  Fly  1487 RSPSPAESPGAEKMLPMSSIQNDFYD---------QEFSTHMERNPRER-LVRHIGAVKDCNLE- 1540
            .|.|.....|      |||.:....|         :..:.|:.::.|:: ..|.|.::..|:.:
plant   431 ASGSDFCEAG------MSSSRRKARDGKQCKVVQTKTSARHLRKSSRKKQSERDIESIFKCSKQK 489

  Fly  1541 TVDLVESEGVAAWATLPRLTRYPGLILLNGNSRCHGRMSPVALPEDPLTMRFPVSPLLRSCGEEL 1605
            ...|:::...:.|....:.|.    |.|..|:          :|.|               |...
plant   490 RSSLLKTSRSSEWGLPSKTTE----IFLQSNN----------IPYD---------------GPPH 525

  Fly  1606 RKTQQMELGMGPLGNNNNNNYQQKNQNVILALPASASENIAGVLRDLANLLHLAPALTCKIIEDK 1670
            .:.|:.:      ||.||..:.:.:.|          .|:.|..|::.     |.:.:|..::.|
plant   526 HEPQRSQ------GNLNNGEHNRSSHN----------GNVEGSNRNIQ-----ASSGSCLRLKVK 569

  Fly  1671 I-----------------GNKL---------------------EDQFMN-QDDEKHVDFKRPLSQ 1696
            .                 ||.|                     ||:... :..|..|:...|:.:
plant   570 FGKSGGQNPLNITVSKVSGNSLPGNGIVKAGTCLELPGSAHFGEDKMQTVETKEDLVEKSNPVEK 634

  Fly  1697 VSHGHLRKILNGRRK--------LCRSCGNVV-----HATGLRVPRHSVPALEEQLPRLAQLMDM 1748
            ||  :|:...:.|.|        |||..|..|     |.:.:|:       :||
plant   635 VS--YLQSSDSMRDKKYNQDAGGLCRKVGGDVLDDDPHLSSIRM-------VEE----------- 679

  Fly  1749 LPRKSVPPPFVYFCDRACFARFKWNGKDGQAEAASLLLQPAGGSAV--KSSNGDSPGSFCASSTA 1811
                         |:||...:    ..|.:....|.::.....|.|  :...|...|.|    :.
plant   680 -------------CERATGTQ----SLDAETSPDSEVINSVPDSIVNIEHKEGLHHGFF----ST 723

  Fly  1812 PAEMVVKQ---EPEDE--DEKTPSVPGNPTNIPAQRKCIVKCFSADCFTTDSAPSGLELDGTAGA 1871
            |.::|.|.   |.|||  ..|:||..|:.. ||..:|.             ..|.      :...
plant   724 PEDVVKKNRVLEKEDELRASKSPSENGSHL-IPNAKKA-------------KHPK------SKSN 768

  Fly  1872 GTGAGPVNNTVWETETSGLQLE-----DTRQCVFCNQRGDGQADGP-----------SRLLNFDV 1920
            ||..|  .:...|:...|.:.|     :.|:.:..:. |...:|.|           ..||:.|:
plant   769 GTKKG--KSKFSESAKDGRKNESHEGVEQRKSLNTSM-GRDDSDYPEVGRIESHKTTGALLDADI 830

  Fly  1921 DKWVHLNCALWSNGVYETVSGALMNFQTALQAGLSQACSACHQPGATIKCFKSRCNSLYHLPCAI 1985
            .|         ::..|.|:|..:.:.:..:...:..:.|.   ..|.::|
plant   831 GK---------TSATYGTISSDVTHGEMVVDVTIEDSYST---ESAWVRC--------------- 868

  Fly  1986 REECVFYKNKSVHCSVHGHAHAGITMGAGAGATTGAGLGGSVADNELSSLVVHRRVFVDRDENRQ 2050
             ::|  :|.:.:..||                      .||:.::.       |.:.::..:.|
plant   869 -DDC--FKWRRIPASV----------------------VGSIDESS-------RWICMNNSDKR- 900

  Fly  2051 VATVMHYSELSNLLRVGNMTF---LNVGQLLPHQLEAFHTPHYIYPIGYKVSRYYWCVRRPNRRC 2112
                  :::.|....:.|...   |.:||   .:.:|
plant   901 ------FADCSKSQEMSNEEINEELGIGQ---DEADA---------------------------- 928

  Fly  2113 RYICSIAEAGCKPEFRIQVQDAGDKEPEREFRGSSPSAVWQQIL--QPITRLRKVHKWLQLFPQH 2175
             |.|..|:.|            .:||.:.:.......|.::.|.  |.:.|.||.....::...|
plant   929 -YDCDAAKRG------------KEKEQKSKRLTGKQKACFKAIKTNQFLHRNRKSQTIDEIMVCH 980

  Fly  2176 I--SGEDLFGLTEPAIVRILESLPGIETLTDYRFKYGRNPLLEFPLAINPSGAARTEPKQRQLLV 2238
            .  |.:...|..|..:.|:|    .||.|
plant   981 CKPSPDGRLGCGEECLNRML----NIECL------------------------------------ 1005

  Fly  2239 WRKPHTQRTAGSCSTQRMANSAAIAGEVACPYSKQFVHSKSSQYKKMKQEWRNNVYLARSKIQGL 2303
                     .|:|.          ||::..  ::||...|..::::.           :|..:|.
plant  1006 ---------QGTCP----------AGDLCS--NQQFQKRKYVKFERF-----------QSGKKGY 1038

  Fly  2304 GLYAARDIEKHTMIIEYIGEVIRTEVSEIREKQYESK-NRGIYMFRLDEDRVVDATLSGGLARYI 2367
            ||....|:.:...:|||:|||:..:..|.|:|:|..| .:..|...|:.:.|:||...|.|.|:|
plant  1039 GLRLLEDVREGQFLIEYVGEVLDMQSYETRQKEYAFKGQKHFYFMTLNGNEVIDAGAKGNLGRFI 1103

  Fly  2368 NHSCNPNCVTEIVEVDRDVRIIIFAKRKIYRGEELSYDYKFDIEDESHKIPCACGAPNCRKWM 2430
            ||||.|||.||...|:.::.:.||:.:.:.:|:||::||.:.....:....|.||:.:||.::
plant  1104 NHSCEPNCRTEKWMVNGEICVGIFSMQDLKKGQELTFDYNYVRVFGAAAKKCYCGSSHCRGYI 1166

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trr	NP_726773.2	PHA03255	184..>320	CDD:165513
		PRK13914	<623..>851	CDD:237555
		ePHD2_KMT2C_like	1898..2002	CDD:277136	16/114 (14%)
		FYRN	2067..2118	CDD:461787	7/53 (13%)
		FYRC	2126..2215	CDD:197781	17/92 (18%)
		SET_KMT2C_2D	2278..2430	CDD:380948	48/152 (32%)
EFS	NP_177854.6	zf-CW	865..910	CDD:462181	10/98 (10%)
		AWS	975..1025	CDD:197795	15/110 (14%)
		SET_SETD2	1025..1167	CDD:380949	47/153 (31%)