Protein Alignment trr and SDG25

DIOPT Version :10

• Sequence 1: NP_726773.2
• Gene: trr / 31149
• FlyBaseID: FBgn0023518
• Length: 2431
• Species: Drosophila melanogaster
• Sequence 2: NP_001318731.1
• Gene: SDG25 / 834246
• AraportID: AT5G42400
• Length: 1388
• Species: Arabidopsis thaliana
• Alignment Length: 541
• Identity: 146/541 - (26%)
• Similarity: 208/541 - (38%)
• Gaps: 155/541 - (28%)

  Fly  1967 TIKCFKSRCNSLYHLPCAIREECVFYKNKSVHCSVHGHAHAGITMGAGAGATTGA-----GLGGS 2026
            |:.| |....||.:.|.        .|.|..|.|.....:.......|..:..||     .:.|.
plant   927 TVDC-KDHEESLSNKPS--------QKVKKAHTSKLKRKNLSDARDEGTKSCNGAVKSFTEISGK 982

  Fly  2027 VADNE-----LSSLVVHRRVFVDRDENRQVATVMHYSELSNLLRVGNMTFLNVGQLLPHQLEAFH 2086
            ..|.|     :|..|.|:.:    .:.|:.....:..::||  ..||...|..|:....
plant   983 EGDTESLGLAISDKVSHQNL----SKRRKKDAAKNGQDMSN--PTGNPPRLAEGKKFVE------ 1035

  Fly  2087 TPHYIYPIGYKVSRYYWCVRRPNRRCRYICSIAEAGCKPEFRIQVQDAGDKEPEREFRGSSPSAV 2151
                                      :..|||::.|                     |.||.|::
plant  1036 --------------------------KSACSISQKG---------------------RKSSQSSI 1053

  Fly  2152 WQQILQPITRLRKVHKWLQLFPQHISGEDLFGLTEPAIVRILESLPGIETLTDYRFKYGRNPLLE 2216
            .::..|...::..|....:|.......||.. :.|...||..|.|| ..| :|...|.|.|.|:.
plant  1054 LKRKHQLDEKISNVPSRRRLSLSSTDSEDAV-IKEDYDVRNEEKLP-CHT-SDKLQKVGPNKLIR 1115

  Fly  2217 -------------------------FPLAINPSGAARTEPKQRQLLV-----------------W 2239
                                     .|:|:.|.....::|.:::|.:                 |
plant  1116 RRKPLAKHTTERSPIKDLSVDDGRPKPIALKPLEKLSSKPSKKKLFLSIPKSDGCARTSINGWHW 1180

  Fly  2240 RK------------------PHTQRTAGSCS-TQRM----ANSAAIAGEVACPYSKQFVHSKSSQ 2281
            ..                  .|.|......| ||.:    .|.|.:...:|.......:  |.||
plant  1181 HAWSLKASAEERARVRGSSCVHMQHFGSKSSLTQNVLSARTNRAKLRNLLAAADGADVL--KMSQ 1243

  Fly  2282 YKKMKQEWRNNVYLARSKIQGLGLYAARDIEKHTMIIEYIGEVIRTEVSEIREKQYESKNRG-IY 2345
            .|..|:..|    ..:|||...||.|...||....:|||:||:||:.:|||||:|||....| .|
plant  1244 LKARKKHLR----FQQSKIHDWGLVALEPIEAEDFVIEYVGELIRSSISEIRERQYEKMGIGSSY 1304

  Fly  2346 MFRLDEDRVVDATLSGGLARYINHSCNPNCVTEIVEVDRDVRIIIFAKRKIYRGEELSYDYKFDI 2410
            :||||:..|:|||..||:||:|||||.|||.|:|:.|:...:|.|:|||.|..|||:||:|||.:
plant  1305 LFRLDDGYVLDATKRGGIARFINHSCEPNCYTKIISVEGKKKIFIYAKRHIDAGEEISYNYKFPL 1369

  Fly  2411 EDESHKIPCACGAPNCRKWMN 2431
            ||:  ||||.||||.||..:|
plant  1370 EDD--KIPCNCGAPKCRGSLN 1388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trr	NP_726773.2	PHA03255	184..>320	CDD:165513
		PRK13914	<623..>851	CDD:237555
		ePHD2_KMT2C_like	1898..2002	CDD:277136	10/34 (29%)
		FYRN	2067..2118	CDD:461787	5/50 (10%)
		FYRC	2126..2215	CDD:197781	20/88 (23%)
		SET_KMT2C_2D	2278..2430	CDD:380948	80/152 (53%)
SDG25	NP_001318731.1	SET_SETD1	1237..1384	CDD:380946	78/154 (51%)