Protein Alignment trr and Setmar

DIOPT Version :10

• Sequence 1: NP_726773.2
• Gene: trr / 31149
• FlyBaseID: FBgn0023518
• Length: 2431
• Species: Drosophila melanogaster
• Sequence 2: NP_848478.2
• Gene: Setmar / 74729
• MGIID: 1921979
• Length: 309
• Species: Mus musculus
• Alignment Length: 327
• Identity: 75/327 - (22%)
• Similarity: 115/327 - (35%)
• Gaps: 108/327 - (33%)

  Fly  2148 PSAVWQQILQPITRLRKVHKWLQLFPQHISGEDLFGLTEPAIVRILESLPGIETLTDYRFKYGRN 2212
            |.::|....:|..      |..|..|.|::|                  ||.:.
Mouse    37 PVSLWPLGAEPRP------KPFQYTPDHVAG------------------PGADI----------- 66

  Fly  2213 PLLEFPLAINPSGAARTEPKQRQLLVWRKPHTQRTAGSCSTQRMANSAAIAGEVACPYSKQF-VH 2276
                .|..|...|.|..|             |....|:||..|..|:          |.... :.
Mouse    67 ----DPTQITFPGCACIE-------------TPCVPGTCSCLRHENN----------YDDNLCLR 104

  Fly  2277 SKSSQYKKMKQEWRNNVYL-----ARSKI----------------QGLGLYAARDIEKHTMIIEY 2320
            ...|:.|..|..:..||..     .|:::                :|.||.....|.|...:.||
Mouse   105 DVGSEGKYAKPVFECNVLCQCGMRCRNRVVQNGLHFLLQVFQTEKKGWGLRTLEFIPKGRFVCEY 169

  Fly  2321 IGEVIRTEVSEIREK-QYESKNRGIYMFRLDE--------DRVVDATLSGGLARYINHSCNPNCV 2376
            .|||:  ..||::.: ..::.:...|:..:.|        :..||.|..|.:.|::||||.||.:
Mouse   170 AGEVL--GFSEVQRRIHLQTSHDSNYIIAVREHIYSGQIMETFVDPTYIGNIGRFLNHSCEPNLL 232

  Fly  2377 TEIVEVDRDV-RIIIFAKRKIYRGEELSYDY------------KFDIEDESHKIPCACGAPNCRK 2428
            ...|.:|..| ::.:||.:.|..||||||||            |..|:....:.||.|||.:|..
Mouse   233 MIPVRIDSMVPKLALFAAKDILPGEELSYDYSGRFLNQVSSKDKEKIDCSPPRKPCYCGAQSCTT 297

  Fly  2429 WM 2430
            ::
Mouse   298 FL 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trr	NP_726773.2	PHA03255	184..>320	CDD:165513
		PRK13914	<623..>851	CDD:237555
		ePHD2_KMT2C_like	1898..2002	CDD:277136
		FYRN	2067..2118	CDD:461787
		FYRC	2126..2215	CDD:197781	10/66 (15%)
		SET_KMT2C_2D	2278..2430	CDD:380948	53/194 (27%)
Setmar	NP_848478.2	SET_SETMAR	50..304	CDD:380942	72/308 (23%)