DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trr and ezh1

DIOPT Version :9

Sequence 1:	NP_726773.2	Gene:	trr / 31149	FlyBaseID:	FBgn0023518	Length:	2431	Species:	Drosophila melanogaster
Sequence 2:	NP_001035072.2	Gene:	ezh1 / 664754	ZFINID:	ZDB-GENE-050114-1	Length:	756	Species:	Danio rerio

Alignment Length:	142	Identity:	55/142 - (38%)
Similarity:	82/142 - (57%)	Gaps:	5/142 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly  2271 SKQFVHSKSSQYKKMKQEWRNNVYLARSKIQGLGLYAARDIEKHTMIIEYIGEVIRTEVSEIREK 2335
            |||......|..:.:|:    ::.||.|.:.|.|.:....::|:..|.||.||:|..:.::.|.:
Zfish   606 SKQVSCKNCSIQRGLKK----HLLLAPSDVAGWGTFIKEPVQKNEFISEYCGELISQDEADRRGR 666

  Fly  2336 QYESKNRGIYMFRLDEDRVVDATLSGGLARYINHSCNPNCVTEIVEVDRDVRIIIFAKRKIYRGE 2400
            .|: |....::|.|:.|.|||||..|...|:.|||.||||..::|.|:.|.||.|||||.|.:||
Zfish   667 IYD-KYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQQGE 730

  Fly  2401 ELSYDYKFDIED 2412
            ||.:||::...|
Zfish   731 ELFFDYRYSQAD 742

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trr	NP_726773.2	PHA03255	184..>320	CDD:165513
		ePHD2_KMT2C_like	1898..2002	CDD:277136
		FYRN	2068..2118	CDD:283589
		FYRC	2126..2215	CDD:197781
		SET	<2266..2431	CDD:225491	55/142 (39%)
		SET	2291..2413	CDD:214614	50/122 (41%)
		PostSET	2415..2431	CDD:214703
ezh1	NP_001035072.2	EZH2_WD-Binding	45..73	CDD:288468
		SANT	447..489	CDD:238096
		SET	<476..736	CDD:225491	52/134 (39%)
		SET	622..743	CDD:214614	50/126 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593892
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840