DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trr and Tbrg1

DIOPT Version :9

Sequence 1:	NP_726773.2	Gene:	trr / 31149	FlyBaseID:	FBgn0023518	Length:	2431	Species:	Drosophila melanogaster
Sequence 2:	NP_001009344.2	Gene:	Tbrg1 / 300521	RGDID:	1305123	Length:	406	Species:	Rattus norvegicus

Alignment Length:	273	Identity:	59/273 - (21%)
Similarity:	109/273 - (39%)	Gaps:	78/273 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly  1986 REECVFYKNK--SVHCSVHGHAHA-------------GITMGA----GAGATTGAGLGGSVADNE 2031
            :||..:...|  .:|....|...|             |:|...    |||.:|||
  Rat    69 KEERRYLLKKLLQIHALTEGEPQAAAPSHSSSLPLAYGVTSSVGTIQGAGPSTGA---------- 123

  Fly  2032 LSSLVVHRRVFVDRD---------ENRQVATVMHYSELSNL----------------------LR 2065
                   ...|..:.         ||.::..:...|:...:                      :.
  Rat   124 -------EEPFAKKSKKEKKEKGKENSKLEVLKKTSKRKKMEGGARKLVRPIALDPSGQPVFPIG 181

  Fly  2066 VGNMTFLNVGQLLPHQLEAFHTPHYIYPIGYKVSRYYWCVRRPNRRCRYICSIAEAGCKPEFRIQ 2130
            :|.:|..::|:::.:: ..||..:.|||:||..:|.|..::.|:::|.|.|.|.:.|.:|:|.|.
  Rat   182 LGGLTVYSLGEIITNR-PGFHDENAIYPVGYCSTRVYASMKCPDQKCLYTCQIKDGGVQPQFEIV 245

  Fly  2131 VQDAGDKEPEREFRGSSPSAVWQQILQPITRLRKVHKWLQLFPQHIS-GEDLFGLTEPAIVRILE 2194
            .:|    :|.....|||..|.::::|:.|:....     :|.|..:| |.|.||.:.|.|..:::
  Rat   246 PED----DPRNTIVGSSADACYEELLRAISAATG-----KLMPNPLSCGADFFGFSHPTIHNLIQ 301

  Fly  2195 SLPGIETLTDYRF 2207
            |.|..:...:|::
  Rat   302 SCPEAQNCVNYQW 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trr	NP_726773.2	PHA03255	184..>320	CDD:165513
		ePHD2_KMT2C_like	1898..2002	CDD:277136	4/17 (24%)
		FYRN	2068..2118	CDD:283589	15/49 (31%)
		FYRC	2126..2215	CDD:197781	22/83 (27%)
		SET	<2266..2431	CDD:225491
		SET	2291..2413	CDD:214614
		PostSET	2415..2431	CDD:214703
Tbrg1	NP_001009344.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	116..144		9/44 (20%)
		FYRN	183..233	CDD:399155	16/50 (32%)
		FYRC	239..320	CDD:399156	23/85 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810