DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment trr and set2

DIOPT Version :9

Sequence 1:	NP_726773.2	Gene:	trr / 31149	FlyBaseID:	FBgn0023518	Length:	2431	Species:	Drosophila melanogaster
Sequence 2:	NP_594980.1	Gene:	set2 / 2542070	PomBaseID:	SPAC29B12.02c	Length:	798	Species:	Schizosaccharomyces pombe

Alignment Length:	179	Identity:	65/179 - (36%)
Similarity:	90/179 - (50%)	Gaps:	10/179 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly  2249 GSCSTQRMANSAAIAGEVACPYSKQFVHSKSSQYKKMKQEWRNNVYLARSKIQGLGLYAARDIEK 2313
            ||....||.:......:..|..|.|....:..::.|:      :|:|...|  |.||.|..::.|
pombe   146 GSNCINRMTSIECTDEDNVCGPSCQNQRFQRHEFAKV------DVFLTEKK--GFGLRADANLPK 202

  Fly  2314 HTMIIEYIGEVIRTEVSEIREKQYESKN-RGIYMFRLDEDRVVDATLSGGLARYINHSCNPNCVT 2377
            .|.:.|||||||..:....|.:||:|:. :..|...|.:...:|||..|.|||:.||||.|||..
pombe   203 DTFVYEYIGEVIPEQKFRKRMRQYDSEGIKHFYFMMLQKGEYIDATKRGSLARFCNHSCRPNCYV 267

  Fly  2378 EIVEVDRDVRIIIFAKRKIYRGEELSYDYKFDIEDESHKIPCACGAPNC 2426
            :...|...:|:.||.||.|.|||||::||..| ...:...||.||.|.|
pombe   268 DKWMVGDKLRMGIFCKRDIIRGEELTFDYNVD-RYGAQAQPCYCGEPCC 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trr	NP_726773.2	PHA03255	184..>320	CDD:165513
		ePHD2_KMT2C_like	1898..2002	CDD:277136
		FYRN	2068..2118	CDD:283589
		FYRC	2126..2215	CDD:197781
		SET	<2266..2431	CDD:225491	61/162 (38%)
		SET	2291..2413	CDD:214614	51/122 (42%)
		PostSET	2415..2431	CDD:214703	6/12 (50%)
set2	NP_594980.1	AWS	125..179	CDD:197795	7/32 (22%)
		SET	180..303	CDD:214614	52/131 (40%)
		SET	275..791	CDD:225491	20/42 (48%)
		PostSET	304..320	CDD:214703	6/12 (50%)
		Med26	440..489	CDD:285873
		SRI	699..771	CDD:285448
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4489
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940