Protein Alignment CG14805 and crb3

DIOPT Version :10

• Sequence 1: NP_569954.1
• Gene: CG14805 / 31146
• FlyBaseID: FBgn0023514
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_593710.1
• Gene: crb3 / 2542844
• PomBaseID: SPAC13G7.08C
• Length: 446
• Species: Schizosaccharomyces pombe
• Alignment Length: 469
• Identity: 106/469 - (22%)
• Similarity: 198/469 - (42%)
• Gaps: 102/469 - (21%)

  Fly     3 DAVEALFISTSSEDNTTCSVQDLRTGTDLMRYKGGGCAQHHSLNMIHLNYVMAANSAKPLLHVWP 67
            :|:|      ....|..|  .:|.|||.:..::....|::.:...  ||::::|...:|.|::..
pombe     9 EAIE------GEPSNVLC--HNLHTGTLVSTFRQSSPAKNATCTT--LNHLLSAQHTRPQLNIHN 63

  Fly    68 INKQEQMAGLRFVVPGKVNALALTPDGNFLVAGIQE-NIYLWHMSSGRMLNTLSKHYQAITCLRF 131
            ..|  ::.....::|..:..:..:|.|::|.||.:: |:|:|.:.||.::.....|||.:|.|:|
pombe    64 FGK--EILDQSIILPEILICVQSSPCGSWLAAGTEKGNLYIWSLKSGALIYFFRAHYQPLTILKF 126

  Fly   132 TDNGEHFISGGKDGAVLVW--------DLTFSAAPLDTGGGKDSTEPLYSFNDHGLAVTDLYSGI 188
            :::|....:...||.|..|        :.||..:       ..|.:.:..|:.|..::..:..|.
pombe   127 SNDGMVLFTASNDGDVFAWLISTLVDQNSTFETS-------NSSVKAISHFSGHKRSIVSMEIGP 184

  Fly   189 GGIRS-YLYTVSLDRCCKVYDLCGGVLLLSVVFPVALHSVIVSKMETRVYVGSSDGKVFV----- 247
            |.|.| .|||.|.|...:::|:..|.||.::..|.....:.|...|..||||:..|.:::
pombe   185 GPIVSGRLYTASEDNTIRIWDVSTGNLLTTIALPSTPSCMTVDPSERVVYVGNEKGIIWIPLYTG 249

  Fly   248 ---FNMENAPRMKEYHLEGEEIQAFVGH-----TYGKA-----------ITCLALNISATTLVSG 293
               |:.....:.:...::...|...:|.     .|..:           ||.|.::..|:.|:||
pombe   250 SSTFSNNVKEKKRVTSVDNTTIPNAIGGMGRVVDYNDSRESSIISCQSPITTLTVSFDASLLISG 314

  Fly   294 GEDNQVCVWDVGSRQLIKSLSQKGSVTNLHIRLLSPAIFLP-EHKQPQMFADS------LKRMIS 351
            .:|..|.|||..|||:::.|          ::..||..||. :..:...:::|      |||||:
pombe   315 DKDGNVLVWDSVSRQVLRRL----------VQYYSPVSFLQCKVDKISFYSNSSLSFPVLKRMIT 369

  Fly   352 ----PWDENDCI------ELFDPDYSGGRKTPELDYTQSHPGTDEEIILKLIASMSSGKNEDDEG 406
                ..|...||      :|..|                      |.|||:.:.:.:..:|....
pombe   370 NEYLNSDVRICIQDDGVEQLMQP----------------------ENILKISSDIVTQGSESSWR 412

  Fly   407 IEAETKATDVEDSE 420
            .:|||....:::::
pombe   413 AKAETSEMQLKEAK 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14805	NP_569954.1	WD40	<55..322	CDD:441893	72/300 (24%)
		WD40 repeat	86..121	CDD:293791	10/35 (29%)
		WD40 repeat	126..162	CDD:293791	10/43 (23%)
		WD40 repeat	172..219	CDD:293791	15/47 (32%)
		WD40 repeat	224..270	CDD:293791	9/53 (17%)
		WD40 repeat	278..315	CDD:293791	16/36 (44%)
		WD40 repeat	319..363	CDD:293791	14/60 (23%)
crb3	NP_593710.1	WD40 repeat	44..74	CDD:293791	6/33 (18%)
		WD40 repeat	81..116	CDD:293791	10/34 (29%)
		WD40	<85..342	CDD:441893	69/273 (25%)
		WD40 repeat	122..172	CDD:293791	12/56 (21%)
		WD40 repeat	177..216	CDD:293791	13/38 (34%)
		WD40 repeat	224..256	CDD:293791	8/31 (26%)
		WD40 repeat	299..336	CDD:293791	16/46 (35%)