Protein Alignment Vps26 and PEP8

DIOPT Version :9

• Sequence 1: NP_569952.2
• Gene: Vps26 / 31144
• FlyBaseID: FBgn0014411
• Length: 478
• Species: Drosophila melanogaster
• Sequence 2: NP_012482.1
• Gene: PEP8 / 853393
• SGDID: S000003589
• Length: 379
• Species: Saccharomyces cerevisiae
• Alignment Length: 376
• Identity: 125/376 - (33%)
• Similarity: 195/376 - (51%)
• Gaps: 91/376 - (24%)

  Fly     6 FGQSADIEIVFDGAE---HKTAEVKGEDGKV----EKMLLFYDGETVSGKVNVTLKKPGSKLEHQ 63
            |....||||:||..|   |.....:..:...    |.:.::.|||::.|.|.:.: :...|::|.
Yeast     5 FKPPIDIEILFDNEESRKHVDIATRSSNSSYKSMKESLPVYEDGESLGGIVTLRV-RDSKKVDHL 68

  Fly    64 GIKIEFIGQIELYYDRGNHH---------------------------EFKCLAKALARPGDLIQN 101
            |||:..||.|::....|:.:                           :|.|.:..|...|:|..:
Yeast    69 GIKVSVIGSIDMLKSHGSGNSSSKKVTSSTSSSSSNGSVDVRKNSVDQFLCQSYDLCPAGELQHS 133

  Fly   102 NSYPFDFPKVEKQFEVYAGSNVRLRYFLRATIVRRISDITK----------EVDIAVHTLCS--- 153
            .|:||.|..:.|::|.|.|.||.:.|:::.|::|:.:||:|          .|..|.:||.:
Yeast   134 QSFPFLFRDLSKRYESYKGKNVDVAYYVKVTVMRKSTDISKIKRFWVYLYNSVTTAPNTLSANET 198

  Fly   154 --------------------------------------YPEMNN---PIKMEVGIEDCLHIEFEY 177
                                                  ....||   |:::::|||:||||||||
Yeast   199 KATTNDIAGGNYAADNASDNTQTKSTQGEAADVNQVLPISHSNNEPKPVRLDIGIENCLHIEFEY 263

  Fly   178 NKSKYHLRDTIIGKIYFLLVRIKIKHMEIAIIKKESTGTGPTMFNENETIAKYEIMDGAPVKGES 242
            .||:|.|::.|:|:|||||.|::|||||:::|.:||:|...:....:.|..:||||||:.||||:
Yeast   264 AKSQYSLKEVIVGRIYFLLTRLRIKHMELSLITRESSGLQTSNVMTDSTAIRYEIMDGSSVKGET 328

  Fly   243 IPIRVFLAGYNLTPTMRDINKKFSVKYFLNLVLMDTEDRRYFKQQEITLWR 293
            ||||:||:||:|||.|.  ...|:||.:|:||::|.:.||||||.||||:|
Yeast   329 IPIRLFLSGYDLTPNMS--CNYFNVKNYLSLVIIDEDGRRYFKQSEITLYR 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps26	NP_569952.2	Vps26	6..280	CDD:146336	114/361 (32%)
PEP8	NP_012482.1	Vps26	5..364	CDD:397622	114/361 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343979
Domainoid	1	1.000	176	1.000	Domainoid score	I729
eggNOG	1	0.900	-	-		E1_KOG3063
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	199	1.000	Inparanoid score	I863
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53681
OrthoFinder	1	1.000	-	-		FOG0001850
OrthoInspector	1	1.000	-	-		oto99621
orthoMCL	1	0.900	-	-		OOG6_101403
Panther	1	1.100	-	-	LDO	PTHR12233
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1646
SonicParanoid	1	1.000	-	-		X1209
TreeFam	1	0.960	-	-
	14	13.790